Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Esther M. M. Smeets"'
Autor:
Theodorus J.P. Jansen, Sevilay Tokgöz, Mijke Buitinga, Sanne A.M. van Lith, Lieke Joosten, Cathelijne Frielink, Esther M. M. Smeets, Martijn W.J. Stommel, Marion B. van der Kolk, Bastiaan E. de Galan, Maarten Brom, Marti Boss, Martin Gotthardt
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Background Estimation of beta cell mass is currently restricted to evaluating pancreatic tissue samples, which provides limited information. A non-invasive imaging technique that reliably quantifies beta cell mass enables monitoring of chang
Externí odkaz:
https://doaj.org/article/32f406a66a7a4f579892ea9495c91ece
Autor:
Irina Heid, Corinna Münch, Sinan Karakaya, Smiths S. Lueong, Alina M. Winkelkotte, Sven T. Liffers, Laura Godfrey, Phyllis F. Y. Cheung, Konstantinos Savvatakis, Geoffrey J. Topping, Florian Englert, Lukas Kritzner, Martin Grashei, Andrea Tannapfel, Richard Viebahn, Heiner Wolters, Waldemar Uhl, Deepak Vangala, Esther M. M. Smeets, Erik H. J. G. Aarntzen, Daniel Rauh, Wilko Weichert, Jörg D. Hoheisel, Stephan A. Hahn, Franz Schilling, Rickmer Braren, Marija Trajkovic-Arsic, Jens T. Siveke
Publikováno v:
Cancer & Metabolism, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) lacks effective treatment options beyond chemotherapy. Although molecular subtypes such as classical and QM (quasi-mesenchymal)/basal-like with transcriptome-based distinct signatures have b
Externí odkaz:
https://doaj.org/article/bde08f1443834615a3f9cb25e23e0e2b
Autor:
Phyllis F. Cheung, JiaJin Yang, Rui Fang, Arianna Borgers, Kirsten Krengel, Anne Stoffel, Kristina Althoff, Chi Wai Yip, Elaine H. L. Siu, Linda W. C. Ng, Karl S. Lang, Lamin B. Cham, Daniel R. Engel, Camille Soun, Igor Cima, Björn Scheffler, Jana K. Striefler, Marianne Sinn, Marcus Bahra, Uwe Pelzer, Helmut Oettle, Peter Markus, Esther M. M. Smeets, Erik H. J. G. Aarntzen, Konstantinos Savvatakis, Sven-Thorsten Liffers, Smiths S. Lueong, Christian Neander, Anna Bazarna, Xin Zhang, Annette Paschen, Howard C. Crawford, Anthony W. H. Chan, Siu Tim Cheung, Jens T. Siveke
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Immune responses to pancreatic ductal adenocarcinoma can be inhibited by cancer cells. Here the authors show that high levels of progranulin in PDAC inhibits immune responses by reducing MHC class I antigen presentation through enhanced degradation o
Externí odkaz:
https://doaj.org/article/c9aa189db2194c2eba13f30f461a6fdd
Autor:
Esther M. M. Smeets, Daphne N. Dorst, Gerben M. Franssen, Merijn S. van Essen, Cathelijne Frielink, Martijn W. J. Stommel, Marija Trajkovic-Arsic, Phyllis F. Cheung, Jens T. Siveke, Ian Wilson, Alessandro Mascioni, Erik H. J. G. Aarntzen, Sanne A. M. van Lith
Publikováno v:
Cells, Vol 12, Iss 10, p 1420 (2023)
Fibroblast activation protein (FAP), expressed on cancer-associated fibroblasts, is a target for diagnosis and therapy in multiple tumour types. Strategies to systemically deplete FAP-expressing cells show efficacy; however, these induce toxicities,
Externí odkaz:
https://doaj.org/article/6aff23dd68ac4fd7aa278e29c1b723ca
Autor:
Esther M. M. Smeets, Dominique S. Withaar, Willem Grootjans, John J. Hermans, Kees van Laarhoven, Lioe-Fee de Geus-Oei, Martin Gotthardt, Erik H. J. G. Aarntzen
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Purpose Metabolic parameters are increasingly being used to characterize tumors. Motion artifacts due to patient respiration introduce uncertainties in quantification of metabolic parameters during positron emission tomography (PET) image ac
Externí odkaz:
https://doaj.org/article/5cae0deabab54c5abdd3e82e17c38473
Autor:
Yvonne H. W. Derks, Melline G. M. Schilham, Mark Rijpkema, Esther M. M. Smeets, Helene I. V. Amatdjais-Groenen, Annemarie Kip, Sanne A. M. van Lith, Jill van de Kamp, J. P. Michiel Sedelaar, Diederik M. Somford, Michiel Simons, Peter Laverman, Martin Gotthardt, Dennis W. P. M. Löwik, Sandra Heskamp, Susanne Lütje
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging, 50, 9, pp. 2872-2884
Purpose Incomplete resection of prostate cancer (PCa) results in increased risk of disease recurrence. Combined fluorescence-guided surgery with tumor-targeted photodynamic therapy (tPDT) may help to achieve complete tumor eradication. We developed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7ecbc1450682f82ccc894d8216083a3
https://repository.ubn.ru.nl/handle/2066/294532
https://repository.ubn.ru.nl/handle/2066/294532
Publikováno v:
Medical Imaging 2022: Digital and Computational Pathology.
Pancreatic cancer will soon be the second leading cause of cancer-related death in Western society. Imaging techniques such as CT, MRI and ultrasound typically help providing the initial diagnosis, but histopathological assessment is still the gold s
Autor:
Esther M M, Smeets, Dominique S, Withaar, Willem, Grootjans, John J, Hermans, Kees, van Laarhoven, Lioe-Fee, de Geus-Oei, Martin, Gotthardt, Erik H J G, Aarntzen
Publikováno v:
EJNMMI Research
Purpose Metabolic parameters are increasingly being used to characterize tumors. Motion artifacts due to patient respiration introduce uncertainties in quantification of metabolic parameters during positron emission tomography (PET) image acquisition
Autor:
Pierpaolo Vendittelli, John-Melle Bokhorst, Esther M M Smeets, Valentyna Kryklyva, Lodewijk A A Brosens, Caroline Verbeke, Geert Litjens
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0301969 (2024)
PurposeThis study aims to introduce an innovative multi-step pipeline for automatic tumor-stroma ratio (TSR) quantification as a potential prognostic marker for pancreatic cancer, addressing the limitations of existing staging systems and the lack of
Externí odkaz:
https://doaj.org/article/5396fd8176d643d3a4cf86ad29f0cdfc