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Autor:
Guido N. J. Tytgat, Jan B.M.J. Jansen, Pauline de Wit, C. M. G. Sunnen, Rene H. M. te Morsche, Mark H. Van Roosmalen, W. P. Paulij, M. P. Cooreman, Esther M. E. Schoondermark-van de Ven
Publikováno v:
Hepatology. 30:1287-1292
The hepatitis B surface antigen (HBsAg) "a" domain harbors major B-cell epitopes. Viruses with mutations in this region emerge after vaccination or during hepatitis B immune globulin (HBIg) prophylaxis. A strain with G145R replacement has been almost