Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Esther Lips"'
Autor:
Deborah Collyar, Mathilde Matthea Machteld Almekinders, Jos Jonkers, Charlotta Mulder, Esther Lips
Publikováno v:
Nature Reviews Cancer. 22:663-678
Autor:
Patrycja Gazinska, Charlotte Milton, Jacopo Iacovacci, Joseph Ward, Richard Buus, Thanussuyah Alaguthurai, Rosalind Graham, Ayse Akarca, Esther Lips, Kalnisha Naidoo, Jelle Wesseling, Teresa Marafioti, Maggie Cheang, Cheryl Gillett, Yin Wu, Aadil Khan, Alan Melcher, Roberto Salgado, Mitch Dowsett, Andrew Tutt, Ioannis Roxanis, Syed Haider, Sheeba Irshad
Publikováno v:
Clinical Cancer Research. 28:4494-4508
Purpose: To identify potential immune targets in post-neoadjuvant chemotherapy (NAC)–resistant triple-negative breast cancer (TNBC) and ER+HER2– breast cancer disease. Experimental Design: Following pathology review, 153 patients were identified
Autor:
Sheeba Irshad, Syed Haider, Ioannis Roxanis, Andrew Tutt, Mitch Dowsett, Roberto Salgado, Alan Melcher, Aadil Khan, Yin Wu, Cheryl Gillett, Maggie Cheang, Teresa Marafioti, Jelle Wesseling, Kalnisha Naidoo, Esther Lips, Ayse Akarca, Rosalind Graham, Thanussuyah Alaguthurai, Richard Buus, Joseph Ward, Jacopo Iacovacci, Charlotte Milton, Patrycja Gazinska
Supplementary Data from Dynamic Changes in the NK-, Neutrophil-, and B-cell Immunophenotypes Relevant in High Metastatic Risk Post Neoadjuvant Chemotherapy–Resistant Early Breast Cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11bdf077fc6d6dd8c21f3d4689e8a136
https://doi.org/10.1158/1078-0432.22488345.v1
https://doi.org/10.1158/1078-0432.22488345.v1
Autor:
Sheeba Irshad, Syed Haider, Ioannis Roxanis, Andrew Tutt, Mitch Dowsett, Roberto Salgado, Alan Melcher, Aadil Khan, Yin Wu, Cheryl Gillett, Maggie Cheang, Teresa Marafioti, Jelle Wesseling, Kalnisha Naidoo, Esther Lips, Ayse Akarca, Rosalind Graham, Thanussuyah Alaguthurai, Richard Buus, Joseph Ward, Jacopo Iacovacci, Charlotte Milton, Patrycja Gazinska
Supplementary Figure from Dynamic Changes in the NK-, Neutrophil-, and B-cell Immunophenotypes Relevant in High Metastatic Risk Post Neoadjuvant Chemotherapy–Resistant Early Breast Cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a90ac325e4ea4104b5c74dea910e71b
https://doi.org/10.1158/1078-0432.22488333.v1
https://doi.org/10.1158/1078-0432.22488333.v1
Autor:
Sheeba Irshad, Syed Haider, Ioannis Roxanis, Andrew Tutt, Mitch Dowsett, Roberto Salgado, Alan Melcher, Aadil Khan, Yin Wu, Cheryl Gillett, Maggie Cheang, Teresa Marafioti, Jelle Wesseling, Kalnisha Naidoo, Esther Lips, Ayse Akarca, Rosalind Graham, Thanussuyah Alaguthurai, Richard Buus, Joseph Ward, Jacopo Iacovacci, Charlotte Milton, Patrycja Gazinska
Purpose:To identify potential immune targets in post-neoadjuvant chemotherapy (NAC)–resistant triple-negative breast cancer (TNBC) and ER+HER2– breast cancer disease.Experimental Design:Following pathology review, 153 patients were identified as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e40a24c6ba425cfc4f07a27c59609d
https://doi.org/10.1158/1078-0432.c.6532695.v1
https://doi.org/10.1158/1078-0432.c.6532695.v1
Autor:
Dik C. van Gent, Agnes Jager, John W.M. Martens, Roland Kanaar, Harmen J.G. van de Werken, Marcel Smid, Petra M. Nederlof, Esther Lips, Winand N.M. Dinjens, T. Dorine den Toom, Hendrikus-Jan Dubbink, Hein F.B.M. Sleddens, Michael A. den Bakker, Carolien H.M. van Deurzen, Kishan A.T. Naipal, Job van Riet, Anieta M. Sieuwerts, Nicole S. Verkaik, Titia G. Meijer
BRCA1 promoter hypermethylation and RNA in situ hybridization by RNAscope. M248, M253, M112 and M232 clearly showed presence of BRCA1 RNA, whereas in M94 (BRCA1 deletion) no BRCA1 RNA was present. M131 and M277 showed heterogeneous presence of BRCA1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2827c3e4bd4d34908bd75437d10a77c8
https://doi.org/10.1158/1078-0432.22467974
https://doi.org/10.1158/1078-0432.22467974
Autor:
Dik C. van Gent, Agnes Jager, John W.M. Martens, Roland Kanaar, Harmen J.G. van de Werken, Marcel Smid, Petra M. Nederlof, Esther Lips, Winand N.M. Dinjens, T. Dorine den Toom, Hendrikus-Jan Dubbink, Hein F.B.M. Sleddens, Michael A. den Bakker, Carolien H.M. van Deurzen, Kishan A.T. Naipal, Job van Riet, Anieta M. Sieuwerts, Nicole S. Verkaik, Titia G. Meijer
Microsatellite instability. Pentaplex PCR showed presence of MSI in M77 and M188.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e10d13c0d322b38e30f5bb21089643
https://doi.org/10.1158/1078-0432.22467968
https://doi.org/10.1158/1078-0432.22467968
Autor:
Jos Jonkers, Sabine Linn, Rita Schmutzler, Birgid Schömig-Markiefka, Peter Mallmann, Reinhard Büttner, H. Christian Reinhardt, Eric Hahnen, Kerstin Rhiem, Michael Hauptmann, Maarten van Lohuizen, Carlos Caldas, Luka Ozretić, Gaurav Kumar Pandey, Wolfram Malter, Fabinshy Thangarajah, Christian Eichler, Jelle Wesseling, René Bernards, Olaf van Tellingen, Peter Bouwman, Chiara Brambillasca, Marieke van de Ven, Tesa Severson, Esther Lips, Katarzyna Jóźwiak, Philip C. Schouten, Mark Opdam, Julian Puppe
Purpose:BRCA1-deficient breast cancers carry a specific DNA copy-number signature (“BRCA1-like”) and are hypersensitive to DNA double-strand break (DSB) inducing compounds. Here, we explored whether (i) EZH2 is overexpressed in human BRCA1-defici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0343f589c44d150610860349dab17486
https://doi.org/10.1158/1078-0432.c.6528062.v1
https://doi.org/10.1158/1078-0432.c.6528062.v1
Autor:
Dik C. van Gent, Agnes Jager, John W.M. Martens, Roland Kanaar, Harmen J.G. van de Werken, Marcel Smid, Petra M. Nederlof, Esther Lips, Winand N.M. Dinjens, T. Dorine den Toom, Hendrikus-Jan Dubbink, Hein F.B.M. Sleddens, Michael A. den Bakker, Carolien H.M. van Deurzen, Kishan A.T. Naipal, Job van Riet, Anieta M. Sieuwerts, Nicole S. Verkaik, Titia G. Meijer
Supplemental legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2844bf2940ef6a51fe1e222feac5900e
https://doi.org/10.1158/1078-0432.22467965
https://doi.org/10.1158/1078-0432.22467965
Autor:
Dik C. van Gent, Agnes Jager, John W.M. Martens, Roland Kanaar, Harmen J.G. van de Werken, Marcel Smid, Petra M. Nederlof, Esther Lips, Winand N.M. Dinjens, T. Dorine den Toom, Hendrikus-Jan Dubbink, Hein F.B.M. Sleddens, Michael A. den Bakker, Carolien H.M. van Deurzen, Kishan A.T. Naipal, Job van Riet, Anieta M. Sieuwerts, Nicole S. Verkaik, Titia G. Meijer
Comparison of mutational signature analysis using all WGS-derived somatic mutations versus using somatic mutations present on SureSelect v5 target regions only.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf22b44cf77d42f91508978d5effb8b
https://doi.org/10.1158/1078-0432.22467971.v1
https://doi.org/10.1158/1078-0432.22467971.v1