Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Esther Kong"'
Autor:
Elena Zaikova, Brian Y. C. Cheng, Viviana Cerda, Esther Kong, Daniel Lai, Amy Lum, Cherie Bates, Wendie den Brok, Takako Kono, Sylvie Bourque, Angela Chan, Xioalan Feng, David Fenton, Anagha Gurjal, Nathalie Levasseur, Caroline Lohrisch, Sarah Roberts, Tamara Shenkier, Christine Simmons, Sara Taylor, Diego Villa, Ruth Miller, Rosalia Aguirre-Hernandez, Samuel Aparicio, Karen Gelmon
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Circulating tumour DNA (ctDNA) detection via liquid biopsy is an emerging alternative to tissue biopsy, but its potential in treatment response monitoring and prognosis in triple negative breast cancer (TNBC) is not yet well understood. Here
Externí odkaz:
https://doaj.org/article/8d2ce9df04da4b8887485568500718ae
Autor:
Peter Eirew, Ciara O’Flanagan, Jerome Ting, Sohrab Salehi, Jazmine Brimhall, Beixi Wang, Justina Biele, Teresa Algara, So Ra Lee, Corey Hoang, Damian Yap, Steven McKinney, Cherie Bates, Esther Kong, Daniel Lai, Sean Beatty, Mirela Andronescu, Elena Zaikova, Tyler Funnell, Nicholas Ceglia, Stephen Chia, Karen Gelmon, Colin Mar, Sohrab Shah, Andrew Roth, Alexandre Bouchard-Côté, Samuel Aparicio
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Gene fitness and essentiality analyses using in vivo cancer models are challenging due to multiple confounders. Here, the authors develop a quantitative approach to study CRISPR-transduced patient-derived xenografts, which they use to analyse in vivo
Externí odkaz:
https://doaj.org/article/5fd8470d7bc644e19c6718168d7a7669
Autor:
Ciara H. O’Flanagan, Kieran R. Campbell, Allen W. Zhang, Farhia Kabeer, Jamie L. P. Lim, Justina Biele, Peter Eirew, Daniel Lai, Andrew McPherson, Esther Kong, Cherie Bates, Kelly Borkowski, Matt Wiens, Brittany Hewitson, James Hopkins, Jenifer Pham, Nicholas Ceglia, Richard Moore, Andrew J. Mungall, Jessica N. McAlpine, The CRUK IMAXT Grand Challenge Team, Sohrab P. Shah, Samuel Aparicio
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Single-cell RNA sequencing (scRNA-seq) is a powerful tool for studying complex biological systems, such as tumor heterogeneity and tissue microenvironments. However, the sources of technical and biological variation in primary sol
Externí odkaz:
https://doaj.org/article/fa6f78c27ad142aba9a969b1f7cd721c
Autor:
Tyler Funnell, Shinya Tasaki, Arusha Oloumi, Shinsuke Araki, Esther Kong, Damian Yap, Yusuke Nakayama, Christopher S. Hughes, S.-W. Grace Cheng, Hirokazu Tozaki, Misa Iwatani, Satoshi Sasaki, Tomohiro Ohashi, Tohru Miyazaki, Nao Morishita, Daisuke Morishita, Mari Ogasawara-Shimizu, Momoko Ohori, Shoichi Nakao, Masatoshi Karashima, Masaya Sano, Aiko Murai, Toshiyuki Nomura, Noriko Uchiyama, Tomohiro Kawamoto, Ryujiro Hara, Osamu Nakanishi, Karey Shumansky, Jamie Rosner, Adrian Wan, Steven McKinney, Gregg B. Morin, Atsushi Nakanishi, Sohrab Shah, Hiroyoshi Toyoshiba, Samuel Aparicio
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
The phosphorylation of serine/arginine-rich proteins by CDC-like kinase is a central regulatory mechanism for RNA splicing reactions. Here, the authors synthesize a novel small molecule CLK inhibitor and map CLK-responsive alternative splicing events
Externí odkaz:
https://doaj.org/article/5aad2179e7e647afa20357dc81dea1bc
Publikováno v:
European Journal Of Family Business. 9:85-101
Family businesses play an important role in the growth of global economy, and while they are arguably perceived as a conservative form of organization with high risk aversion and reluctance to change, counterintuitive empirical evidence show that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ae71b17c812fd31b9e15c7b4441c3d7
https://doi.org/10.24310/ejfbejfb.v9i2.5678
https://doi.org/10.24310/ejfbejfb.v9i2.5678
Autor:
Peter Eirew, Ciara O’Flanagan, Jerome Ting, Sohrab Salehi, Jazmine Brimhall, Beixi Wang, Justina Biele, Teresa Algara, So Ra Lee, Corey Hoang, Damian Yap, Steven McKinney, Cherie Bates, Esther Kong, Daniel Lai, Sean Beatty, Mirela Andronescu, Elena Zaikova, Tyler Funnell, Nicholas Ceglia, Stephen Chia, Karen Gelmon, Colin Mar, Sohrab Shah, Andrew Roth, Alexandre Bouchard-Côté, Samuel Aparicio
Publikováno v:
Nature communications. 13(1)
Assessing tumour gene fitness in physiologically-relevant model systems is challenging due to biological features of in vivo tumour regeneration, including extreme variations in single cell lineage progeny. Here we develop a reproducible, quantitativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d82413c3a5f0d91a6500088bcc254e
https://pubmed.ncbi.nlm.nih.gov/35927228
https://pubmed.ncbi.nlm.nih.gov/35927228
Autor:
Esther Kong, Annie Koh
Publikováno v:
Succession and Innovation in Asia’s Small-and-Medium-Sized Enterprises ISBN: 9789811590146
This chapter traces the growth and development of Small Medium Enterprises (SMEs) from post-independent Singapore in 1965 to its current day digital transformation age. Singapore’s SME landscape has evolved from one of low wage, low productivity en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65a0ecd55572640f298f87769551ff1a
https://doi.org/10.1007/978-981-15-9015-3_7
https://doi.org/10.1007/978-981-15-9015-3_7
Autor:
Annie Koh, Esther Kong
Publikováno v:
Succession and Innovation in Asia’s Small-and-Medium-Sized Enterprises ISBN: 9789811590146
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f5c300732d0a08ea7a37d654b4473cc
https://doi.org/10.1007/978-981-15-9015-3_15
https://doi.org/10.1007/978-981-15-9015-3_15
Autor:
Sohrab P. Shah, Allen W. Zhang, Nicholas Ceglia, Samuel Aparicio, Daniel Lai, Peter Eirew, Justina Biele, Esther Kong, Richard D. Moore, Kieran R Campbell, Cherie Bates, Jamie L. P. Lim, Jenifer Pham, Matt Wiens, Kelly Borkowski, Andrew McPherson, Farhia Kabeer, Andrew J. Mungall, Ciara H. O'Flanagan, James Hopkins, Jessica N. McAlpine, Brittany Hewitson
Publikováno v:
Genome Biology
Genome Biology, Vol 20, Iss 1, Pp 1-13 (2019)
Genome Biology, Vol 20, Iss 1, Pp 1-13 (2019)
BackgroundSingle-cell RNA sequencing (scRNAseq) is a powerful tool for studying complex biological systems, such as tumour heterogeneity and tissue microenvironments. However, the sources of technical and biological variation in primary solid tumour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2dfacc0c474158c0cc38d7e9e0d3faa
https://doi.org/10.1101/683227
https://doi.org/10.1101/683227
Autor:
Damian Yap, Nao Morishita, Atsushi Nakanishi, Karey Shumansky, Shinsuke Araki, Shoichi Nakao, Satoshi Sasaki, Esther Kong, Ryujiro Hara, Momoko Ohori, Hiroyoshi Toyoshiba, Adrian Wan, Masatoshi Karashima, Mari Ogasawara-Shimizu, Osamu Nakanishi, Hirokazu Tozaki, Christopher S. Hughes, Noriko Uchiyama, S.-W. Grace Cheng, Masaya Sano, Daisuke Morishita, Tomohiro Kawamoto, Tohru Miyazaki, Shinya Tasaki, Jamie Rosner, Tyler Funnell, Sohrab P. Shah, Arusha Oloumi, Toshiyuki Nomura, Samuel Aparicio, Steven McKinney, Yusuke Nakayama, Tomohiro Ohashi, Aiko Murai, Gregg B. Morin, Misa Iwatani
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
CDC-like kinase phosphorylation of serine/arginine-rich proteins is central to RNA splicing reactions. Yet, the genomic network of CDC-like kinase-dependent RNA processing events remains poorly defined. Here, we explore the connectivity of genomic CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7743b0b42973b00a9e04e84cdd5eb466
https://doi.org/10.1038/s41467-016-0008-7
https://doi.org/10.1038/s41467-016-0008-7