Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Esther Kaplun"'
Autor:
Rona Yaeger, Riccardo Mezzadra, Jenna Sinopoli, Yu Bian, Michelangelo Marasco, Esther Kaplun, Yijun Gao, HuiYong Zhao, Arnaud Da Cruz Paula, Yingjie Zhu, Almudena Chaves Perez, Kalyani Chadalavada, Edison Tse, Sudhir Chowdhry, Sydney Bowker, Qing Chang, Besnik Qeriqi, Britta Weigelt, Gouri J. Nanjangud, Michael F. Berger, Hirak Der-Torossian, Kenna Anderes, Nicholas D. Socci, Jinru Shia, Gregory J. Riely, Yonina R. Murciano-Goroff, Bob T. Li, James G. Christensen, Jorge S. Reis-Filho, David B. Solit, Elisa de Stanchina, Scott W. Lowe, Neal Rosen, Sandra Misale
Publikováno v:
Cancer Discovery. :OF1-OF15
With the combination of KRASG12C and EGFR inhibitors, KRAS is becoming a druggable target in colorectal cancer. However, secondary resistance limits its efficacy. Using cell lines, patient-derived xenografts, and patient samples, we detected a hetero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d232aac4bf14933900750105086f2b
https://doi.org/10.1158/2159-8290.cd-22-0405
https://doi.org/10.1158/2159-8290.cd-22-0405
Autor:
Sandra Misale, Neal Rosen, Scott W. Lowe, Elisa de Stanchina, David B. Solit, Jorge S. Reis-Filho, James G. Christensen, Bob T. Li, Yonina R. Murciano-Goroff, Gregory J. Riely, Jinru Shia, Nicholas D. Socci, Kenna Anderes, Hirak Der-Torossian, Michael F. Berger, Gouri J. Nanjangud, Britta Weigelt, Besnik Qeriqi, Qing Chang, Sydney Bowker, Sudhir Chowdhry, Edison Tse, Kalyani Chadalavada, Almudena Chaves Perez, Yingjie Zhu, Arnaud Da Cruz Paula, HuiYong Zhao, Yijun Gao, Esther Kaplun, Michelangelo Marasco, Yu Bian, Jenna Sinopoli, Riccardo Mezzadra, Rona Yaeger
With the combination of KRASG12C and EGFR inhibitors, KRAS is becoming a druggable target in colorectal cancer. However, secondary resistance limits its efficacy. Using cell lines, patient-derived xenografts, and patient samples, we detected a hetero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321acf5988c203cec453f0f9392a6cbb
https://doi.org/10.1158/2159-8290.c.6549768
https://doi.org/10.1158/2159-8290.c.6549768
Autor:
Sandra Misale, Neal Rosen, Scott W. Lowe, Elisa de Stanchina, David B. Solit, Jorge S. Reis-Filho, James G. Christensen, Bob T. Li, Yonina R. Murciano-Goroff, Gregory J. Riely, Jinru Shia, Nicholas D. Socci, Kenna Anderes, Hirak Der-Torossian, Michael F. Berger, Gouri J. Nanjangud, Britta Weigelt, Besnik Qeriqi, Qing Chang, Sydney Bowker, Sudhir Chowdhry, Edison Tse, Kalyani Chadalavada, Almudena Chaves Perez, Yingjie Zhu, Arnaud Da Cruz Paula, HuiYong Zhao, Yijun Gao, Esther Kaplun, Michelangelo Marasco, Yu Bian, Jenna Sinopoli, Riccardo Mezzadra, Rona Yaeger
Generation of acquired resistance PDX model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b112c15ea1771670c6a5c8e6aa44819
https://doi.org/10.1158/2159-8290.22541925.v1
https://doi.org/10.1158/2159-8290.22541925.v1
Autor:
Sandra Misale, Neal Rosen, Scott W. Lowe, Elisa de Stanchina, David B. Solit, Jorge S. Reis-Filho, James G. Christensen, Bob T. Li, Yonina R. Murciano-Goroff, Gregory J. Riely, Jinru Shia, Nicholas D. Socci, Kenna Anderes, Hirak Der-Torossian, Michael F. Berger, Gouri J. Nanjangud, Britta Weigelt, Besnik Qeriqi, Qing Chang, Sydney Bowker, Sudhir Chowdhry, Edison Tse, Kalyani Chadalavada, Almudena Chaves Perez, Yingjie Zhu, Arnaud Da Cruz Paula, HuiYong Zhao, Yijun Gao, Esther Kaplun, Michelangelo Marasco, Yu Bian, Jenna Sinopoli, Riccardo Mezzadra, Rona Yaeger
Characterization of acquired resistance in vitro models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f67ce7610e48806cbaecce32c2ecb5
https://doi.org/10.1158/2159-8290.22541934
https://doi.org/10.1158/2159-8290.22541934
Autor:
Sandra Misale, Neal Rosen, Scott W. Lowe, Elisa de Stanchina, David B. Solit, Jorge S. Reis-Filho, James G. Christensen, Bob T. Li, Yonina R. Murciano-Goroff, Gregory J. Riely, Jinru Shia, Nicholas D. Socci, Kenna Anderes, Hirak Der-Torossian, Michael F. Berger, Gouri J. Nanjangud, Britta Weigelt, Besnik Qeriqi, Qing Chang, Sydney Bowker, Sudhir Chowdhry, Edison Tse, Kalyani Chadalavada, Almudena Chaves Perez, Yingjie Zhu, Arnaud Da Cruz Paula, HuiYong Zhao, Yijun Gao, Esther Kaplun, Michelangelo Marasco, Yu Bian, Jenna Sinopoli, Riccardo Mezzadra, Rona Yaeger
Oncoprint of baseline alterations in CRC patients who developed resistance to KRAS G12C and EGFR inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f1e5f0b69f42344348c333a68349703
https://doi.org/10.1158/2159-8290.22541922
https://doi.org/10.1158/2159-8290.22541922
Autor:
Sandra Misale, Neal Rosen, Scott W. Lowe, Elisa de Stanchina, David B. Solit, Jorge S. Reis-Filho, James G. Christensen, Bob T. Li, Yonina R. Murciano-Goroff, Gregory J. Riely, Jinru Shia, Nicholas D. Socci, Kenna Anderes, Hirak Der-Torossian, Michael F. Berger, Gouri J. Nanjangud, Britta Weigelt, Besnik Qeriqi, Qing Chang, Sydney Bowker, Sudhir Chowdhry, Edison Tse, Kalyani Chadalavada, Almudena Chaves Perez, Yingjie Zhu, Arnaud Da Cruz Paula, HuiYong Zhao, Yijun Gao, Esther Kaplun, Michelangelo Marasco, Yu Bian, Jenna Sinopoli, Riccardo Mezzadra, Rona Yaeger
C106 resistant cells drug withdrawal and Patient #12 MSK-Impact data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::721a27ac24ffaf19b9a34afef5d70fdb
https://doi.org/10.1158/2159-8290.22541916.v1
https://doi.org/10.1158/2159-8290.22541916.v1
Autor:
Sandra Misale, Neal Rosen, Scott W. Lowe, Elisa de Stanchina, David B. Solit, Jorge S. Reis-Filho, James G. Christensen, Bob T. Li, Yonina R. Murciano-Goroff, Gregory J. Riely, Jinru Shia, Nicholas D. Socci, Kenna Anderes, Hirak Der-Torossian, Michael F. Berger, Gouri J. Nanjangud, Britta Weigelt, Besnik Qeriqi, Qing Chang, Sydney Bowker, Sudhir Chowdhry, Edison Tse, Kalyani Chadalavada, Almudena Chaves Perez, Yingjie Zhu, Arnaud Da Cruz Paula, HuiYong Zhao, Yijun Gao, Esther Kaplun, Michelangelo Marasco, Yu Bian, Jenna Sinopoli, Riccardo Mezzadra, Rona Yaeger
Patients Progression Cell Free DNA data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2103f98339db3653ec1f01ea60631758
https://doi.org/10.1158/2159-8290.22541910
https://doi.org/10.1158/2159-8290.22541910
Autor:
Sandra Misale, Neal Rosen, Scott W. Lowe, Elisa de Stanchina, David B. Solit, Jorge S. Reis-Filho, James G. Christensen, Bob T. Li, Yonina R. Murciano-Goroff, Gregory J. Riely, Jinru Shia, Nicholas D. Socci, Kenna Anderes, Hirak Der-Torossian, Michael F. Berger, Gouri J. Nanjangud, Britta Weigelt, Besnik Qeriqi, Qing Chang, Sydney Bowker, Sudhir Chowdhry, Edison Tse, Kalyani Chadalavada, Almudena Chaves Perez, Yingjie Zhu, Arnaud Da Cruz Paula, HuiYong Zhao, Yijun Gao, Esther Kaplun, Michelangelo Marasco, Yu Bian, Jenna Sinopoli, Riccardo Mezzadra, Rona Yaeger
Patients Characteristics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8082bc5c8753024d6afa5a53f1ef221
https://doi.org/10.1158/2159-8290.22541913
https://doi.org/10.1158/2159-8290.22541913
Autor:
Sandra Misale, Neal Rosen, Scott W. Lowe, Elisa de Stanchina, David B. Solit, Jorge S. Reis-Filho, James G. Christensen, Bob T. Li, Yonina R. Murciano-Goroff, Gregory J. Riely, Jinru Shia, Nicholas D. Socci, Kenna Anderes, Hirak Der-Torossian, Michael F. Berger, Gouri J. Nanjangud, Britta Weigelt, Besnik Qeriqi, Qing Chang, Sydney Bowker, Sudhir Chowdhry, Edison Tse, Kalyani Chadalavada, Almudena Chaves Perez, Yingjie Zhu, Arnaud Da Cruz Paula, HuiYong Zhao, Yijun Gao, Esther Kaplun, Michelangelo Marasco, Yu Bian, Jenna Sinopoli, Riccardo Mezzadra, Rona Yaeger
C106 cell lines single cell sequencing analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b32fc5e9812019ed0131b69e5e8d148
https://doi.org/10.1158/2159-8290.22541931.v1
https://doi.org/10.1158/2159-8290.22541931.v1
Autor:
Sandra Misale, Neal Rosen, Scott W. Lowe, Elisa de Stanchina, David B. Solit, Jorge S. Reis-Filho, James G. Christensen, Bob T. Li, Yonina R. Murciano-Goroff, Gregory J. Riely, Jinru Shia, Nicholas D. Socci, Kenna Anderes, Hirak Der-Torossian, Michael F. Berger, Gouri J. Nanjangud, Britta Weigelt, Besnik Qeriqi, Qing Chang, Sydney Bowker, Sudhir Chowdhry, Edison Tse, Kalyani Chadalavada, Almudena Chaves Perez, Yingjie Zhu, Arnaud Da Cruz Paula, HuiYong Zhao, Yijun Gao, Esther Kaplun, Michelangelo Marasco, Yu Bian, Jenna Sinopoli, Riccardo Mezzadra, Rona Yaeger
RW7213 cell lines sequencing analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baae97b034fa5ca0238c3573da04fd10
https://doi.org/10.1158/2159-8290.22541928.v1
https://doi.org/10.1158/2159-8290.22541928.v1