Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Esther K. Lee"'
Autor:
Ellen Greenblatt, William Wong, Esther K. Lee, Kelvin K. W. Chan, Ellen Warner, Mahdi Zargar, Joseph H. Lipton
Publikováno v:
Human Reproduction. 35:434-445
STUDY QUESTION Is it cost-effective to use in vitro fertilisation and preimplantation genetic testing of monogenic defects (IVT/PGT-M) to prevent transmission of BRCA1/2 mutations to second-generation new births in comparison with naturally conceived
Publikováno v:
Animal Models for Human Cancer
Autor:
Michelle Shoong, Aditi Vedi, John E. Dick, Mark D. Minden, Gareth Holmes, Shin-ichiro Takayanagi, Chiara Luberto, Stephanie Z. Xie, Kerstin B. Kaufmann, Esther K. Lee, Ishita Patel, Elisa Laurenti, Laura García-Prat, Guy Romm, Olga I. Gan, Joseph Jargstorf, Elvin Wagenblast, Andy G.X. Zeng, Robin Ferrari, Kristele Pan, Veronique Voisin, Gary D. Bader
Publikováno v:
Cell Stem Cell
Summary Cellular stress responses serve as crucial decision points balancing persistence or culling of hematopoietic stem cells (HSCs) for lifelong blood production. Although strong stressors cull HSCs, the linkage between stress programs and self-re
Publikováno v:
Breast Cancer Research and Treatment. 150:169-180
5-fluorouracil, epirubicin, cyclophosphamide → docetaxel (FEC-D) has been associated with higher-than-expected rates of febrile neutropenia (FN) that meet the current guideline threshold of 20 % for primary prophylaxis (PP) with granulocyte colony-
Autor:
Esther K. Lee, Keemo Delos Santos, Kim Blakely, Urban Emmenegger, Annabelle Chow, Van C. Hoang, Maria Carmen Riesco Martinez
Publikováno v:
Medical Hypotheses. 83:482-487
Castration-resistant prostate cancer (CRPC) is an advanced and incurable stage of the second most frequently diagnosed malignancy in men globally. Current treatment options improve survival modestly but eventually fail due to intrinsic or acquired th
Autor:
Esther K. Lee, Urban Emmenegger, Gemma Cramarossa, Soley Georgsdottir, Lavarnan Sivanathan, Kelvin K. W. Chan, Kelly Lien, Keemo Delos Santos
Publikováno v:
Biomarkers in Medicine. 8:893-911
Low-dose metronomic (LDM) chemotherapy is a beneficial and very well-tolerated form of chemotherapy utilization characterized by the frequent and uninterrupted administration of low doses of conventional chemotherapeutic agents over prolonged periods
Autor:
Tiago Medina, Aditi Vedi, Gary D. Bader, Kerstin B. Kaufmann, Ishita Patel, Veronique Voisin, Alex Murison, Elisa Laurenti, Robin Ferrari, John E. Dick, Stephanie Z. Xie, Naoya Takayama, Gareth Holmes, Laura Garcia Prat, Mathieu Lupien, Olga I. Gan, Esther K. Lee, Chiara Luberto
Publikováno v:
Blood. 132:170-170
The hematopoietic stem cells (HSC) field has long been perplexed by how the blood system d (~10e12 cells produced daily) - yet hematologic malignancies remain relatively rare. The risk of malignancy is mitigated in part by a complex hierarchy in whic
Autor:
Carlo DeAngelis, Angie Giotis, Esther K. Lee, Urban Emmenegger, Ronak Saluja, Rehana Jamani, Scott R. Berry
Publikováno v:
European journal of clinical pharmacology. 72(11)
Abiraterone acetate (AA), used to treat metastatic castration-resistant prostate cancer (mCRPC), inhibits androgen biosynthesis by blocking cytochrome P450 (CYP) 17A1. It also inhibits other cytochromes involved in the metabolism of various widely us
Autor:
Erica McDonald, Vanessa Sarah Arciero, Esther K. Lee, Urban Emmenegger, Kelly Lien, Phillip S. Blanchette
Publikováno v:
Journal of Clinical Oncology. 34:e16568-e16568
e16568Background: Abiraterone plus prednisone (AA+P) delays symptomatic progression, palliates symptoms, and improves survival of pts with castration-resistant prostate cancer (CRPC). While inheren...
Publikováno v:
Journal of Clinical Oncology. 33:9626-9626
9626 Background: Guidelines recommend primary prophylaxis (PP) with granulocyte colony stimulating factors (G-CSF) for patients above a febrile neutropenia (FN) risk threshold of 20%. When consider...