Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Esther J. Coy"'
Publikováno v:
International Journal of Peptide and Protein Research. 9:57-62
(Formyl-sarcosine)1-LH-RH (I), (acetyl-sarcosine)1-LH-RH (II), (2-pyrrolidone-4-carboxylic acid)1-LH-RH (III), (N-methyl-2-pyrrolidone-4-carboxylic acid)1-LH-RH (IV, hydroxyproline1-LH-RH (V) and (cyclopentane-carboxylic acid)1-LH-RH (VI) were synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19fe78fcebffd36685eb400287482aee
https://doi.org/10.1111/j.1399-3011.1977.tb01837.x
https://doi.org/10.1111/j.1399-3011.1977.tb01837.x
Publikováno v:
Fertility and Sterility. 26:554-559
The anti-LH-releasing activity of several analogues of LH-RH was tested by 2-hour infusion in ovariectomized, estrogen-progesterone-pretreated rats and in immature male rats. [Leu3]LH-RH, [Leu3, desGly10]-LH-RH ethylamide, [desHis2, Leu3,desGly10]-LH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7054fcdde39c30bdfeaa2716c5717caa
https://doi.org/10.1016/s0015-0282(16)41175-1
https://doi.org/10.1016/s0015-0282(16)41175-1
Publikováno v:
Journal of Medicinal Chemistry. 28:181-185
In previous reports illustrating the effects of conformational restriction of the N-terminal region of human pancreatic growth hormone releasing factor, we demonstrated that D-amino acid substitutions in either of positions 1, 2, or 3 resulted in gre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228011d5a0e524061f15cfebf9748710
https://doi.org/10.1021/jm00380a006
https://doi.org/10.1021/jm00380a006
Publikováno v:
Biochemical and Biophysical Research Communications. 67:576-582
Luteinizing hormone (LH)-releasing activity of 8 potent LH-releasing hormone (RH) analogs was investigated in primary cultures of anterior pituitary cells. Introduction of the C-terminal ethylamide modification into (D-Ala 6) - LH-RH were 90 and 100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d0cbba9ec6267510f61f850fe6d1652
https://doi.org/10.1016/0006-291x(75)90851-7
https://doi.org/10.1016/0006-291x(75)90851-7
Autor:
Jesus A. Vilchez-Martinez, David H. Coy, Esther J. Coy, Akira Arimura, Yoshihiro Hirotsu, Andrew V. Schally
Publikováno v:
Biochemical and Biophysical Research Communications. 59:1226-1232
[Leu 6 ,desGly-NH 2 10 ]-LH-RH ethylamide and [Leu 6 ]-LH-RH, two analogs of LH-RH, were prepared by the solid phase method. LH- and FSH-releasing activity of these peptides was assayed against LH-RH by subcutaneous administration in immature male ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b0d8c128c03755198fecd135a6c98c
https://doi.org/10.1016/0006-291x(74)90445-8
https://doi.org/10.1016/0006-291x(74)90445-8
Autor:
David H. Coy, Jesus A. Vilchez-Martinez, Akira Arimura, Esther J. Coy, Andrew V. Schally, Luciano Debeljuk
Publikováno v:
Endocrinology. 95:213-218
The anti-LH-releasing hormone (LHRH) activity of des-His2-desGly10-LH-RH ethylamide (antagonist I), an analogue of LH-RH, was studied in several animal systems. An iv infusion of antagonist 1 for 2 hr significantly inhibited LH release in response to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e21490bac8f734af83779f605cd4d9bd
https://doi.org/10.1210/endo-95-1-213
https://doi.org/10.1210/endo-95-1-213
Autor:
L. Ferland, M. Beaulieu, Esther J. Coy, Muriel Savary, Fernand Labrie, Andrew V. Schally, David H. Coy
Publikováno v:
Clinical Endocrinology. 5:s279-s289
Improved inhibitors of LH-RH are those which, beside removal of the histidine residue at position 2 of LH-RH, include replacement of glycine at position 6 by a D-amino acid. A still better modification is replacement of the histidine residue at posit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39648528309974d7758980dbd2a04de8
https://doi.org/10.1111/j.1365-2265.1976.tb03836.x
https://doi.org/10.1111/j.1365-2265.1976.tb03836.x
Autor:
Jesus A. Vilchez-Martinez, Esther J. Coy, Andrew V. Schally, David H. Coy, Akira Arimura, N. Nishi
Publikováno v:
Biochemistry. 14:1848-1851
A series of C-terminally fluorinated analogs of luteinizing hormone-releasing hormone (LH-RH) was synthesized by a combination of solid-phase and classical techniques and found to have interesting properties when assayed for LH- and FSH-releasing act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9201f646356bc362b067dfce443506f
https://doi.org/10.1021/bi00680a007
https://doi.org/10.1021/bi00680a007
Autor:
Jean Côté, Esther J. Coy, Pierre Borgeat, F. Ruel, N. Yanaihara, Fernand Labrie, David H. Coy, Andrew V. Schally
Publikováno v:
Molecular and Cellular Endocrinology. 1:7-20
Dose-response studies with des-(pyro) Glu-LH-RH, [Phe 3 ] LH-RH, [Phe 5 ] LH-RH [0-methyl-Tyr 5 ] LH-RH, [Ile 7 ] LH-RH and des-Gly 10 -LH-RH-ethylamide show concomitant stimulation of adenohypophyseal adenosine 3',5'-monophosphate (cyclic AMP) conce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::463f68502d9a90a2d44d9158315cc552
https://doi.org/10.1016/0303-7207(74)90035-5
https://doi.org/10.1016/0303-7207(74)90035-5
Publikováno v:
Fertility and Sterility. 26:889-893
Inhibitory activity of 4 analogs of luteinizing hormone-releasing hormone (LH-RH) in vivo was studied in rats. 30 mcg of (des-His D-Ala )-LH-RH (des-His D-Leu )-LH-RH or (D-Phe D-Leu )-LH-RH in 2 equal doses administered 20 minutes prior and at the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b988d8ff189b20e451c743d1bf386ad2
https://doi.org/10.1016/s0015-0282(16)41353-1
https://doi.org/10.1016/s0015-0282(16)41353-1