Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Esther J, Verschuren"'
Autor:
Jeroen J. A. van Kampen, Esther J. Verschuren, Theo M. Luider, Mariska L. Reedijk, Rob A. Gruters, Albert D. M. E. Osterhaus, Peter C. Burgers, Ronald de Groot
Publikováno v:
Analytica Chimica Acta, 80, 10, pp. 3751-6
Analytica Chimica Acta, 80, 3751-6
Analytical Chemistry, 80(10), 3751-3756. American Chemical Society
Analytica Chimica Acta, 80, 3751-6
Analytical Chemistry, 80(10), 3751-3756. American Chemical Society
Contains fulltext : 71284.pdf (Publisher’s version ) (Open Access) In this report we explore the use of MALDI-FTICR mass spectrometry for the quantitative analysis of five HIV-1 protease inhibitors in cell lysates. 2,5-Dihydroxybenzoic acid (DHB) w
Autor:
Peter C. Burgers, Theo M. Luider, Albert D. M. E. Osterhaus, Esther J. Verschuren, Ronald de Groot, Jeroen J. A. van Kampen, Rob A. Gruters
Publikováno v:
Journal of Chromatography B. Analytical Technologies in the Biomedical and Life Sciences, 847(1), 38-44. Elsevier
Mass spectrometry is a powerful tool for studying the intracellular pharmacokinetics of antiretroviral drugs. However, the biohazard of HIV-1 calls for a safety protocol for such analyses. To this end, we extracted HIV-1 producing cells with methanol
Autor:
Adrianus C. M. Boon, Albert D. M. E. Osterhaus, Rob A. Gruters, Mariska L. Reedijk, Carel A. van Baalen, Esther J. Verschuren, David Kwa, Guus F. Rimmelzwaan, Gerrie de Mutsert
Publikováno v:
Journal of Infectious Diseases, 192(7), 1183-1190. Oxford University Press
Ex vivo detection of virus-specific cytotoxic T lymphocyte (CTL) responses is limited to the use of methods assessing cytokine production, degranulation, or perforin contents of antigen-specific CD8+ T cells. Generally, their cytotoxic activity is de
Autor:
Patrick H. M. Boers, Rob A. Gruters, Carel A. van Baalen, Christophe Guillon, Albert D. M. E. Osterhaus, Minus van Baalen, Esther J. Verschuren
Publikováno v:
European Journal of Immunology. 32:2644-2652
Recent studies indicate that the time required for virus-infected cells to become vulnerable for the activity of CTL is of significance for the capacity of CTL to control ongoing viral reproduction. To investigate whether this applies to the effectiv
Autor:
Walter E.P. Beyer, Joeri L. Aerts, Albert D. M. E. Osterhaus, Patrick Lacor, Marchina E. van der Ende, Mariska L. Reedijk, Kris Thielemans, Carlo Heirman, Rob A. Gruters, Brenda De Keersmaecker, Annelies De Bel, Judith Vandeloo, Anna L. de Goede, Esther J. Verschuren, Jeanette Koetsveld, Frank H. M. Pistoor, Paul H. C. Eilers, Sabine Allard, Iman Padmos, Jurgen Corthals, Carel A. van Baalen, Carolien Wylock
Corrigendum to ‘A phase I/IIa immunotherapy trial of HIV-1-infected patients with Tat, Rev and Nef expressing dendritic cells followed by treatment interruption’ [Clin. Immunol. 142 (2012) 252–268] Sabine D. Allard⁎, Brenda De Keersmaecker, A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370dd79fbfe84af3774f6bd4f62e21ba
https://biblio.vub.ac.be/vubir/corrigendum-to-a-phase-iiia-immunotherapy-trial-of-hiv1infected-patients-with-tat-rev-and-nef-expressing-dendritic-cells-followed-by-treatment-interruption-clin-immunol-142-2012-252268(3cb32d3d-c563-44fd-9cb1-c18735c83925).html
https://biblio.vub.ac.be/vubir/corrigendum-to-a-phase-iiia-immunotherapy-trial-of-hiv1infected-patients-with-tat-rev-and-nef-expressing-dendritic-cells-followed-by-treatment-interruption-clin-immunol-142-2012-252268(3cb32d3d-c563-44fd-9cb1-c18735c83925).html
Autor:
Mariska L. Reedijk, Kris Thielemans, Sabine Allard, Walter E.P. Beyer, Paul H. C. Eilers, Rob A. Gruters, Marchina E. van der Ende, Jurgen Corthals, Carlo Heirman, Patrick Lacor, Joeri L. Aerts, Judith Vandeloo, Iman Padmos, Brenda De Keersmaecker, Albert D. M. E. Osterhaus, Jeanette Koetsveld, Anna L. de Goede, Frank H. M. Pistoor, Esther J. Verschuren, Annelies De Bel, Carel A. van Baalen, Carolien Wylock
Publikováno v:
Clinical Immunology, 142(3), 252-268. Academic Press
In a phase I/IIa clinical trial, 17 HIV-1 infected patients, stable on cART, received 4 vaccinations with autologous dendritic cells etectroporated with mRNA encoding Tat, Rev and Nef, after which cART was interrupted. Vaccination was safe and feasib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d77a4378c0477be912acd6e450f25c3
https://biblio.vub.ac.be/vubir/a-phase-iiia-immunotherapy-trial-of-hiv1infected-patients-with-tat-rev-and-nef-expressing-dendritic-cells-followed-by-treatment-interruption(ccdca1cf-6074-41b0-88e3-0a3d0310fa8d).html
https://biblio.vub.ac.be/vubir/a-phase-iiia-immunotherapy-trial-of-hiv1infected-patients-with-tat-rev-and-nef-expressing-dendritic-cells-followed-by-treatment-interruption(ccdca1cf-6074-41b0-88e3-0a3d0310fa8d).html
Autor:
A.D.M.E. Osterhaus, Martina M. Geelhoed-Mieras, Esther J. Verschuren, Eufemia Berkhoff, Ron A. M. Fouchier, Guus F. Rimmelzwaan, C. A. van Baalen, Rob A. Gruters
Publikováno v:
Clinical & Experimental Immunology, 148(2), 296-306. Wiley-Blackwell Publishing Ltd
SummaryIn the present study, we examined the effect of the loss of the human leucocyte antigen (HLA)-B*3501-restricted nucleoprotein (NP)418–426 epitope on interferon (IFN)-γ-production and lytic activity of the human cytotoxic T lymphocyte (CTL)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd875168840d838635a6aff20714d91
https://pure.eur.nl/en/publications/f06c9c1f-ba44-4656-88ee-0aa37c93f138
https://pure.eur.nl/en/publications/f06c9c1f-ba44-4656-88ee-0aa37c93f138
Autor:
Carel A, van Baalen, Christophe, Guillon, Minus, van Baalen, Esther J, Verschuren, Patrick H M, Boers, Albert D M E, Osterhaus, Rob A, Gruters
Publikováno v:
European journal of immunology. 32(9)
Recent studies indicate that the time required for virus-infected cells to become vulnerable for the activity of CTL is of significance for the capacity of CTL to control ongoing viral reproduction. To investigate whether this applies to the effectiv
Autor:
Carel A. van Baalen, Esther J. Verschuren, Christophe Guillon, Albert D. M. E. Osterhaus, Patrick H. M. Boers, Rob A. Gruters
Publikováno v:
Journal of Virological Methods, 99, 115-121. Elsevier
In this study the construction is described of HIV-1 molecular clones in which CTL epitopes from RT or Env late proteins were inserted into the Nef early protein. The ectopic epitopes were efficiently processed from the recombinant Nef proteins, were