Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Esther Herbert"'
Autor:
Esther Herbert, Diana Papaioannou, Amanda Loban, Nikki Totton, Marie Hyslop, Robert Bolt, Christopher Deery
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-7 (2024)
Abstract Background Improving retention within randomised controlled trials is important. The effectiveness of different strategies can be assessed using a Study Within A Trial (SWAT). Previous research has shown personalised text message reminders i
Externí odkaz:
https://doaj.org/article/82e47dd2fe0e4c2a9017cb8438c221f3
Autor:
Lynda Wyld, Malcolm WR Reed, Karen Collins, Sue Ward, Geoff Holmes, Jenna Morgan, Mike Bradburn, Stephen Walters, Maria Burton, Kate Lifford, Adrian Edwards, Kate Brain, Alistair Ring, Esther Herbert, Thompson G Robinson, Charlene Martin, Tim Chater, Kirsty Pemberton, Anne Shrestha, Anthony Nettleship, Paul Richards, Alan Brennan, Kwok Leung Cheung, Annaliza Todd, Helena Harder, Riccardo Audisio, Nicolo Matteo Luca Battisti, Juliet Wright, Richard Simcock, Christopher Murray, Alastair M Thompson, Margot Gosney, Matthew Hatton, Fiona Armitage, Julietta Patnick, Tracy Green, Deirdre Revill, Jacqui Gath, Kieran Horgan, Chris Holcombe, Matt Winter, Jay Naik, Rishi Parmeshwar
Publikováno v:
Programme Grants for Applied Research, Vol 10, Iss 6 (2022)
Background: In breast cancer management, age-related practice variation is widespread, with older women having lower rates of surgery and chemotherapy than younger women, based on the premise of reduced treatment tolerance and benefit. This may contr
Externí odkaz:
https://doaj.org/article/77f7655fdd404d7cbb72026187c711da
Autor:
Praveen Thokala, Gordon W. Fuller, Steve Goodacre, Samuel Keating, Esther Herbert, Gavin D. Perkins, Andy Rosser, Imogen Gunson, Joshua Miller, Matthew Ward, Mike Bradburn, Tim Harris, Maggie Marsh, Kate Ren, Cindy Cooper
Publikováno v:
BMC Emergency Medicine, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Standard prehospital management for Acute respiratory failure (ARF) involves controlled oxygen therapy. Continuous positive airway pressure (CPAP) is a potentially beneficial alternative treatment, however, it is uncertain whether
Externí odkaz:
https://doaj.org/article/ec3e9608b5a5432884cfa9a4092a4065
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background With millions of pounds spent annually on medical research in the UK, it is important that studies are spending funds wisely. Internal pilots offer the chance to stop a trial early if it becomes apparent that the study will not be
Externí odkaz:
https://doaj.org/article/a8c23bfb8c6248ca938d18eb4afd3470
Autor:
Gordon W Fuller, Samuel Keating, Steve Goodacre, Esther Herbert, Gavin D Perkins, Andy Rosser, Imogen Gunson, Joshua Miller, Matthew Ward, Mike Bradburn, Praveen Thokala, Tim Harris, Margaret M Marsh, Alexander J Scott, Cindy Cooper
Publikováno v:
Health Technology Assessment, Vol 25, Iss 7 (2021)
Background: Acute respiratory failure is a life-threatening emergency. Standard prehospital management involves controlled oxygen therapy. Continuous positive airway pressure is a potentially beneficial alternative treatment; however, it is uncertain
Externí odkaz:
https://doaj.org/article/76bb1a5316a94580a23492751af178d4
Autor:
Steve Goodacre, Tim Harris, Matthew Ward, Cindy Cooper, Mike Bradburn, Alex Scott, Esther Herbert, Gavin Perkins, Andy Rosser, Praveen Thokala, Sam Keating, Imogen Gunson, Josh Miller, Maggie Marsh
Publikováno v:
BMJ Open, Vol 10, Iss 7 (2020)
Objectives To determine the feasibility of a large-scale definitive multicentre trial of prehospital continuous positive airway pressure (CPAP) in acute respiratory failure.Design A single-centre, open-label, individual patient randomised, controlled
Externí odkaz:
https://doaj.org/article/327fde16e4ca4b58954a86fd8dba20ab
Autor:
Rebecca Palmer, Munyaradzi Dimairo, Nicholas Latimer, Elizabeth Cross, Marian Brady, Pam Enderby, Audrey Bowen, Steven Julious, Madeleine Harrison, Abualbishr Alshreef, Ellen Bradley, Arjun Bhadhuri, Tim Chater, Helen Hughes, Helen Witts, Esther Herbert, Cindy Cooper
Publikováno v:
Health Technology Assessment, Vol 24, Iss 19 (2020)
Background: People with aphasia may improve their communication with speech and language therapy many months/years after stroke. However, NHS speech and language therapy reduces in availability over time post stroke. Objective: This trial evaluated t
Externí odkaz:
https://doaj.org/article/c06e17b731fe4bb399e504c271806997
Autor:
Mike Bradburn, John Yianni, Saurabh Sinha, John Newell-Price, Esther Herbert, Lee Walton, Hugh P Sims-Williams, Kaveesha Rajapaksa, Matthias W. R. Radatz
Publikováno v:
Pituitary
Purpose Acromegaly has high morbidity and mortality when growth hormone secretion remains uncontrolled. Stereotactic radiosurgery (SRS) may be used when pituitary surgery is not suitable or unsuccessful, but there are few very long-term safety data a
Autor:
Margot Gosney, Alistair Ring, R. Parmeschwar, Kate Lifford, Deirdre Revill, Lynda Wyld, Jacqui Gath, Jenna Morgan, Annaliza Todd, Geoffrey Holmes, Charlene Martin, Sue Ward, A.M. Thomson, Tim Chater, Anne Shrestha, Malcolm W.R. Reed, Adrian Edwards, Mike Bradburn, Matthew Hatton, Alan Brennan, Kirsty Pemberton, Jay Naik, Christopher Holcombe, Kwok-Leung Cheung, Thompson G. Robinson, J.T. Wright, T. Green, Stephen J Walters, Matthew C Winter, Maria Burton, Karen Collins, Esther Herbert, Riccardo A. Audisio, Richard Simcock, Kieran Horgan
Publikováno v:
British Journal of Surgery. 108:315-325
Background Primary endocrine therapy may be an alternative treatment for less fit women with oestrogen receptor (ER)-positive breast cancer. This study compared quality-of-life (QoL) outcomes in older women treated with surgery or primary endocrine t
Autor:
Lynda Wyld, Richard Simcock, Jacqui Gath, Alan Brennan, Deirdre Revell, Maria Burton, Riccardo A. Audisio, Jay Naik, Malcolm W.R. Reed, Kwok L. Cheung, Geoffrey Holmes, Charlene Martin, Annaliza Todd, Matthew Hatton, Tim Chater, Kirsty Pemberton, Stephen J Walters, Chris Holcombe, Matthew C Winter, Margot Gosney, Thompson G. Robinson, Kate Lifford, Adrian Edwards, A. Ring, Anne Shrestha, Kieran Horgan, Sue Ward, Juliet Wright, Alastair M. Thompson, Karen Collins, Rishi Parmeshwar, Nicolò Matteo Luca Battisti, Esther Herbert, Jenna Morgan, Age Gap Tmg, Tracey Green, Mike Bradburn
Publikováno v:
European Journal of Cancer
Introduction Older patients with early breast cancer (EBC) derive modest survival benefit from chemotherapy but have increased toxicity risk. Data on the impact of chemotherapy for EBC on quality of life in older patients are limited, but this is a k