Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Esther Groettrup-Wolfers"'
Autor:
Hugh S. Taylor, M.D., Liying Dong, M.D., Ph.D., Johanna Haikonen, M.D., Peter Oppelt, M.D., Karl Tamussino, M.D., Rene Wenzl, M.D., Ph.D., Thomas Faustmann, M.D., Esther Groettrup-Wolfers, M.D., Ph.D., Xiaowei Ren, Ph.D., Christian Seitz, M.D., Ph.D.
Publikováno v:
F&S Reports, Vol 5, Iss 2, Pp 189-196 (2024)
Objective: To evaluate the efficacy and safety of 2 doses of vilaprisan vs. placebo in participants with symptomatic endometriosis. Design: Multicenter, randomized, double-blind, placebo-controlled, parallel-group phase 2b trial (NCT03573336). The in
Externí odkaz:
https://doaj.org/article/d8f6b31dc0ed4dc1a5fa02650f0442ca
Autor:
Jan Hilpert, Esther Groettrup-Wolfers, Hristiyan Kosturski, Laura Bennett, Catriona L. K. Barnes, Kerstin Gude, Isabella Gashaw, Stefanie Reif, Thomas Steger-Hartmann, Christian Scheerans, Alexander Solms, Antje Rottmann, Guangping Mao, Charles Chapron
Publikováno v:
Drugs in R&D, Vol 23, Iss 3, Pp 221-237 (2023)
Abstract Introduction BAY1128688 is a selective inhibitor of aldo-keto reductase family 1 member C3 (AKR1C3), an enzyme implicated in the pathology of endometriosis and other disorders. In vivo animal studies suggested a potential therapeutic applica
Externí odkaz:
https://doaj.org/article/1369a10efd534cdaa1fd230aeaa2dd33
Autor:
Kathrin Petersdorf, Esther Groettrup-Wolfers, Paul M. Overton, Christian Seitz, Renate Schulze-Rath
Publikováno v:
European journal of obstetrics, gynecology, and reproductive biology. 271
Hormonal therapies have been associated with a range of effects on the endometrium, including endometrial hyperplasia (EH). With many medicinal products being developed for pre-menopausal women, epidemiological data regarding the population backgroun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ff61091853d3e9266fe17d3ffe517f
https://pubmed.ncbi.nlm.nih.gov/35217456
https://pubmed.ncbi.nlm.nih.gov/35217456
Publikováno v:
Acta obstetricia et gynecologica Scandinavica. 96(6)
Introduction Antagonism of CC chemokine receptor type 1 (CCR1) may provide a novel treatment approach for women with symptomatic endometriosis. Studies of CCR1 antagonists in these patients have not been reported. Material and methods Women (n = 110;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9975982159778b29a80f0c5d65dc622b
https://pubmed.ncbi.nlm.nih.gov/28168715
https://pubmed.ncbi.nlm.nih.gov/28168715