Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Esther Griesbach"'
Autor:
Hasan Vatandaslar, Aitor Garzia, Cindy Meyer, Svenja Godbersen, Laura T. L. Brandt, Esther Griesbach, Jeffrey A. Chao, Thomas Tuschl, Markus Stoffel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract System-wide cross-linking and immunoprecipitation (CLIP) approaches have unveiled regulatory mechanisms of RNA-binding proteins (RBPs) mainly in cultured cells due to limitations in the cross-linking efficiency of tissues. Here, we describe
Externí odkaz:
https://doaj.org/article/e26c38132e814ef1ac94b1becc3a7648
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
H2A.X histone variant gene encodes poly(A)+ and poly(A)- mRNA isoforms which are differentially expressed depending on cell lines. Here the authors show that upon DNA damage, cells expressing more poly(A)+ isoform require this isoform for de novo H2A
Externí odkaz:
https://doaj.org/article/90bcdc21996641338179013236fc44d3
Autor:
Carlota Recio, Daniel Lucy, Gareth S. D. Purvis, Poppy Iveson, Lynda Zeboudj, Asif J. Iqbal, Daniel Lin, Chris O’Callaghan, Lucy Davison, Esther Griesbach, Angela J. Russell, Graham M. Wynne, Lea Dib, Claudia Monaco, David R. Greaves
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
GPR84 is a member of the metabolic G protein-coupled receptor family, and its expression has been described predominantly in immune cells. GPR84 activation is involved in the inflammatory response, but the mechanisms by which it modulates inflammatio
Externí odkaz:
https://doaj.org/article/875d4c14d3c04be38fa8ea6a5323b026
Autor:
Pratik Dave, Gregory Roth, Esther Griesbach, Daniel Mateju, Tobias Hochstoeger, Jeffrey A. Chao
Publikováno v:
Molecular Cell. 83:589-606.e6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49884a0b09dd035bb0c32a1f67af6be6
https://doi.org/10.1016/j.molcel.2023.01.013
https://doi.org/10.1016/j.molcel.2023.01.013
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Phosphorylated H2A.X is a critical chromatin marker of DNA damage repair (DDR) in higher eukaryotes. However, H2A.X gene expression remains relatively uncharacterised. Replication-dependent (RD) histone genes generate poly(A)- mRNA encoding new histo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed554b1a4ade16b4d05f6cefbcd1198
http://europepmc.org/articles/PMC7807067
http://europepmc.org/articles/PMC7807067
Publikováno v:
bioRxiv
SUMMARYThe relationship between mRNA translation and decay is incompletely understood, with conflicting reports suggesting that translation can either promote decay or stabilize mRNAs. The effect of translation on mRNA decay has mainly been studied u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a1cc5252375db692316084b596a126
Publikováno v:
MOLECULAR AND CELLULAR BIOLOGY
The 3' end processing of animal replication-dependent histone mRNAs is activated during G1/S-phase transition. The processing site is recognized by stem-loop binding protein and the U7 snRNP, but cleavage additionally requires a heat-labile factor (H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3dabfeff708778a33647680ec80c0db
https://europepmc.org/articles/PMC4248742/
https://europepmc.org/articles/PMC4248742/
