Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Esther Florin"'
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Subthalamic deep brain stimulation (STN-DBS) is an effective therapy for alleviating motor symptoms in people with Parkinson’s disease (PwP), although some may not receive optimal clinical benefits. One potential mechanism of STN-DBS invol
Externí odkaz:
https://doaj.org/article/be5e7516c0544e45bc98c57d5724df98
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Bradykinesia is a behavioral manifestation that contributes to functional dependencies in later life. However, the current state of bradykinesia indexing primarily relies on subjective, time-averaged categorizations of motor deficits, which
Externí odkaz:
https://doaj.org/article/ea26473ee8cb4304b10d75f1d469d450
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Although subthalamic deep brain stimulation (DBS) is a highly-effective treatment for alleviating motor dysfunction in patients with Parkinson’s disease (PD), clinicians currently lack reliable neurophysiological correlates of clinical out
Externí odkaz:
https://doaj.org/article/3fe36f350fdf4d65ae18a021bfce6131
Publikováno v:
Frontiers in Systems Neuroscience, Vol 17 (2023)
IntroductionParkinson’s disease (PD) is a neurodegenerative disorder affecting the whole brain, leading to several motor and non-motor symptoms. In the past, it has been shown that PD alters resting state networks (RSN) in the brain. These networks
Externí odkaz:
https://doaj.org/article/0c397df154524410b29e5efd42a1fbf5
Subthalamic stimulation evoked cortical responses relate to motor performance in Parkinson's disease
Publikováno v:
Brain Stimulation, Vol 16, Iss 2, Pp 561-563 (2023)
Externí odkaz:
https://doaj.org/article/e7b1f81d1038456996730458b6ee0226
Publikováno v:
Brain Stimulation, Vol 15, Iss 3, Pp 792-802 (2022)
Background: Neuronal oscillations are linked to symptoms of Parkinson's disease. This relation can be exploited for optimizing deep brain stimulation (DBS), e.g. by informing a device or human about the optimal location, time and intensity of stimula
Externí odkaz:
https://doaj.org/article/cc34175278974eecbdb33f29e9f7345b
Autor:
Lucia K. Feldmann, Roxanne Lofredi, Wolf-Julian Neumann, Bassam Al-Fatly, Jan Roediger, Bahne H. Bahners, Petyo Nikolov, Timothy Denison, Assel Saryyeva, Joachim K. Krauss, Katharina Faust, Esther Florin, Alfons Schnitzler, Gerd-Helge Schneider, Andrea A. Kühn
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-9 (2022)
Abstract Adaptive deep brain stimulation (aDBS) is a promising concept for feedback-based neurostimulation, with the potential of clinical implementation with the sensing-enabled Percept neurostimulator. We aim to characterize chronic electrophysiolo
Externí odkaz:
https://doaj.org/article/4d3cbb3df0d6464389a5d20409c483b8
Publikováno v:
NeuroImage: Clinical, Vol 37, Iss , Pp 103317- (2023)
The implantation of deep brain stimulation (DBS) electrodes in Parkinson’s disease (PD) patients can lead to a temporary improvement in motor symptoms, known as the stun effect. However, the network alterations induced by the stun effect are not we
Externí odkaz:
https://doaj.org/article/1384c197166c4a9c958c63773ac7a8a6
Publikováno v:
NeuroImage, Vol 263, Iss , Pp 119619- (2022)
Recent evidence suggests that beta bursts in subthalamic nucleus (STN) play an important role in Parkinsonian pathophysiology.We studied the spatio-temporal relationship between STN beta bursts and cortical activity in 26 Parkinson's disease (PD) pat
Externí odkaz:
https://doaj.org/article/81173e5247f0447fb11eb781ae2235f1
Autor:
Jeroen G. V. Habets, Rachel K. Spooner, Varvara Mathiopoulou, Lucia K. Feldmann, Johannes L. Busch, Jan Roediger, Bahne H. Bahners, Alfons Schnitzler, Esther Florin, Andrea A. Kühn
Publikováno v:
Sensors, Vol 23, Iss 11, p 5238 (2023)
Bradykinesia is a cardinal hallmark of Parkinson’s disease (PD). Improvement in bradykinesia is an important signature of effective treatment. Finger tapping is commonly used to index bradykinesia, albeit these approaches largely rely on subjective
Externí odkaz:
https://doaj.org/article/c4ed289c288241fb818af890b913d9db