Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Esther Eytan"'
Autor:
Timothy J. Yen, Shirly Miniowitz-Shemtov, Sharon Kaisari, Esther Eytan, Song-Tao Liu, Danielle Sitry-Shevah, Avram Hershko, Kexi Wang
Publikováno v:
Proceedings of the National Academy of Sciences. 111:12019-12024
The mitotic (or spindle assembly) checkpoint system delays anaphase until all chromosomes are correctly attached to the mitotic spindle. When the checkpoint is active, a Mitotic Checkpoint Complex (MCC) assembles and inhibits the ubiquitin ligase Ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da31412a29deeb05e61f8b5187f583ce
https://doi.org/10.1073/pnas.1412901111
https://doi.org/10.1073/pnas.1412901111
Publikováno v:
Proceedings of the National Academy of Sciences. 110:10568-10573
The mitotic (or spindle assembly) checkpoint system prevents premature separation of sister chromatids in mitosis. When the checkpoint is turned on, the mitotic checkpoint complex (MCC) inhibits the ubiquitin ligase anaphase-promoting complex/cycloso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abac6d463c51c861b3d45ee873794114
https://doi.org/10.1073/pnas.1308928110
https://doi.org/10.1073/pnas.1308928110
Autor:
Shirly Miniowitz-Shemtov, Elena Dumin, Danielle Sitry-Shevah, Dvora Ganoth, Esther Eytan, Avram Hershko
Publikováno v:
Proceedings of the National Academy of Sciences. 109:8056-8060
The mitotic checkpoint system delays anaphase until all chromosomes are correctly attached to the mitotic spindle. When the checkpoint is turned on, it promotes the formation of the mitotic checkpoint complex (MCC), which inhibits the ubiquitin ligas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf44b2883245fad878fe15c49e621fd3
https://doi.org/10.1073/pnas.1204081109
https://doi.org/10.1073/pnas.1204081109
Autor:
Adar Teichner, Elena Dumin, Jonathan Gromis, Avram Hershko, Danielle Sitry-Shevah, Esther Eytan, Shirly Miniowitz-Shemtov
Publikováno v:
Proceedings of the National Academy of Sciences. 108:3187-3192
Accurate segregation of chromosomes in mitosis is ensured by a surveillance mechanism called the mitotic (or spindle assembly) checkpoint. It prevents sister chromatid separation until all chromosomes are correctly attached to the mitotic spindle thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1821c61be48b623132a9eabc3b95b8b3
https://doi.org/10.1073/pnas.1100023108
https://doi.org/10.1073/pnas.1100023108
Autor:
Tim J. Yen, Dvora Ganoth, Avram Hershko, Esther Eytan, James C. Hittle, Ilana Braunstein, Adar Teichner
Publikováno v:
Proceedings of the National Academy of Sciences. 105:9181-9185
The mitotic checkpoint system ensures the fidelity of chromosome segregation by preventing the completion of mitosis in the presence of any misaligned chromosome. When activated, it blocks the initiation of anaphase by inhibiting the ubiquitin ligase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3996c0b32b9d9cb4b48b2350ac2f14a9
https://doi.org/10.1073/pnas.0804069105
https://doi.org/10.1073/pnas.0804069105
Autor:
Esther Eytan, Eldad J. Dann, Anne Carter, Gera D. Eytan, Tamar Katz, Yael Shechter, Ronit Regev, Jacob M. Rowe, Ana Oliven
Publikováno v:
British Journal of Haematology. 114:581-590
Tetramethylrosamine (TMR) is excluded from P-glycoprotein (MDR1)-enriched cell lines, but it stains efficiently MDR1-poor parent lines. Application of the TMR resistance assay to cells obtained from chronic myelogenous leukaemia (CML) patients reveal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3065e3db7e64d4af33a6e8619b8bf99
https://doi.org/10.1046/j.1365-2141.2001.02969.x
https://doi.org/10.1046/j.1365-2141.2001.02969.x
Publikováno v:
Nature Cell Biology. 1:193-199
Degradation of the mammalian cyclin-dependent kinase (CDK) inhibitor p27 is required for the cellular transition from quiescence to the proliferative state. The ubiquitination and subsequent degradation of p27 depend on its phosphorylation by cyclin-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee9d1649e1b8421c8317bf29e2c31b8
https://doi.org/10.1038/12013
https://doi.org/10.1038/12013
Autor:
Michele Pagano, Francesca Fiore, Alessia Montagnoli, Esther Eytan, Andrea C. Carrano, Giulio Draetta, Avram Hershko
Publikováno v:
Genes & Development. 13:1181-1189
The cellular abundance of the cyclin-dependent kinase (Cdk) inhibitor p27 is regulated by the ubiquitin-proteasome system. Activation of p27 degradation is seen in proliferating cells and in many types of aggressive human carcinomas. p27 can be phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d2c7d6adf66c8df3a4906683070d4c6
https://doi.org/10.1101/gad.13.9.1181
https://doi.org/10.1101/gad.13.9.1181
Autor:
A Hershko, Joan V. Ruderman, L H Cohen, Dvorah Ganoth, Esther Eytan, F. C. Luca, Aviva Dahan, Valery Sudakin
Publikováno v:
Journal of Biological Chemistry. 269:4940-4946
Cyclin B, a positive regulatory subunit of the cdc2 protein kinase complex, is synthesized across the cell cycle and then rapidly degraded at the end of mitosis. Degradation of cyclin B is triggered by increased levels of active cdc2 and is required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8abe9ea7e44ac27a822b303344c3b636
https://doi.org/10.1016/s0021-9258(17)37636-6
https://doi.org/10.1016/s0021-9258(17)37636-6
Publikováno v:
Journal of Biological Chemistry. 268:4668-4674
In the ubiquitin (Ub) system for protein degradation, proteins ligated to Ub are degraded by an ATP-dependent 26 S protease complex. During or after proteolysis, free Ub is regenerated, but the mechanisms of Ub release remained unknown. It was previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e2aa0fd1846b0b64ee728d9fa136fed
https://doi.org/10.1016/s0021-9258(18)53448-7
https://doi.org/10.1016/s0021-9258(18)53448-7