Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Esther Eberhardt"'
Autor:
Barbara Namer, Diana Schmidt, Esther Eberhardt, Michele Maroni, Eva Dorfmeister, Inge Petter Kleggetveit, Luisa Kaluza, Jannis Meents, Aaron Gerlach, Zhixin Lin, Andreas Winterpacht, Elena Dragicevic, Zacharias Kohl, Jürgen Schüttler, Ingo Kurth, Torhild Warncke, Ellen Jorum, Beate Winner, Angelika Lampert
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 401-408 (2019)
Background: Small fiber neuropathy (SFN) is a severe and disabling chronic pain syndrome with no causal and limited symptomatic treatment options. Mechanistically based individual treatment is not available. We report an in-vitro predicted individual
Externí odkaz:
https://doaj.org/article/91146ae9315e46b38077f020b2157149
Autor:
Angelika Lampert, David L. Bennett, Lucy A. McDermott, Anika Neureiter, Esther Eberhardt, Beate Winner, Martin Zenke
Publikováno v:
Neurobiology of Pain, Vol 8, Iss , Pp 100055- (2020)
In this concise Mini-Review we will summarize ongoing developments of new techniques to study physiology and pathophysiology of the peripheral sensory nervous system in human stem cell derived models. We will focus on recent developments of reprogram
Externí odkaz:
https://doaj.org/article/6b64117c1b584beb933c4e3f3347c1e6
Autor:
Esther Eberhardt, Steven Havlicek, Diana Schmidt, Andrea S. Link, Cristian Neacsu, Zacharias Kohl, Martin Hampl, Andreas M. Kist, Alexandra Klinger, Carla Nau, Jürgen Schüttler, Christian Alzheimer, Jürgen Winkler, Barbara Namer, Beate Winner, Angelika Lampert
Publikováno v:
Stem Cell Reports, Vol 5, Iss 3, Pp 305-313 (2015)
Human pluripotent stem cells (hPSCs) offer the opportunity to generate neuronal cells, including nociceptors. Using a chemical-based approach, we generated nociceptive sensory neurons from HUES6 embryonic stem cells and retrovirally reprogrammed indu
Externí odkaz:
https://doaj.org/article/7b938d91ddc44b31834122252d74feb0
Autor:
Andreas M Kist, Dagrun Sagafos, Anthony M Rush, Cristian Neacsu, Esther Eberhardt, Roland Schmidt, Lars Kristian Lunden, Kristin Ørstavik, Luisa Kaluza, Jannis Meents, Zhiping Zhang, Thomas Hedley Carr, Hugh Salter, David Malinowsky, Patrik Wollberg, Johannes Krupp, Inge Petter Kleggetveit, Martin Schmelz, Ellen Jørum, Angelika Lampert, Barbara Namer
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161789 (2016)
Gain-of-function mutations in the tetrodotoxin (TTX) sensitive voltage-gated sodium channel (Nav) Nav1.7 have been identified as a key mechanism underlying chronic pain in inherited erythromelalgia. Mutations in TTX resistant channels, such as Nav1.8
Externí odkaz:
https://doaj.org/article/0ff14342238441cca93dc92d429cbad3
Autor:
Andrias O O'Reilly, Esther Eberhardt, Christian Weidner, Christian Alzheimer, B A Wallace, Angelika Lampert
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41667 (2012)
Bisphenol A (BPA) has attracted considerable public attention as it leaches from plastic used in food containers, is detectable in human fluids and recent epidemiologic studies link BPA exposure with diseases including cardiovascular disorders. As he
Externí odkaz:
https://doaj.org/article/602826e1cac8434da51c579840f00655
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2429
Induced pluripotent stem cells (iPS-cells) have significantly expanded our experimental possibilities, by creating new strategies for the molecular study of human disease and drug development. Treatment of pain has not seen much improvement over the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ed15e4a777ad48f260db28b41460334b
https://pubmed.ncbi.nlm.nih.gov/35507161
https://pubmed.ncbi.nlm.nih.gov/35507161
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619780
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fafd928c6e1b6cf300df107565aae788
https://doi.org/10.1007/978-1-0716-1979-7_11
https://doi.org/10.1007/978-1-0716-1979-7_11
Autor:
Tania Rizo, Lisa Gebhardt, Julia Riedlberger, Esther Eberhardt, Lars Fester, Dalia Alansary, Jürgen Winkler, Soeren Turan, Philipp Arnold, Barbara A Niemeyer, Michael J M Fischer, Beate Winner
Publikováno v:
Brain : a journal of neurology 145(9), 3131–3146 (2022). doi:10.1093/brain/awac122
Brain : a journal of neurology 145(9), 3131–3146 (2022). doi:10.1093/brain/awac122
Published by Oxford Univ. Press, Oxford
Published by Oxford Univ. Press, Oxford
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0629f535c9204c85b61ac6e51a85e6
Autor:
Lucy A. McDermott, Angelika Lampert, Esther Eberhardt, Beate Winner, Martin Zenke, Anika Neureiter, David L.H. Bennett
Publikováno v:
Neurobiology of Pain
Neurobiology of Pain, Vol 8, Iss, Pp 100055-(2020)
Neurobiology of Pain, Vol 8, Iss, Pp 100055-(2020)
Highlights • New techniques emerge to study peripheral sensory neurons in iPS-cell derived models. • Genetic pain syndromes, e.g. gain- and loss-of-function mutations in Nav-channels are helpful. • Individualized treatment for neuropathic pain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7160e156c08dfb1d2838c1326b3f7a3
https://pubmed.ncbi.nlm.nih.gov/33364527
https://pubmed.ncbi.nlm.nih.gov/33364527
Autor:
Jürgen Schüttler, Michele Maroni, Beate Winner, Angelika Lampert, Jannis Körner, Esther Eberhardt
Publikováno v:
Pflugers Archiv : European journal of physiology. 471(11-12)
In cardiomyocytes, electrical activity is coupled to cellular contraction, thus exposing all proteins expressed in the sarcolemma to mechanical stress. The voltage-gated sodium channel Nav1.5 is the main contributor to the rising phase of the action
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08388d382f0368d6a0e62d457ed3180
https://pubmed.ncbi.nlm.nih.gov/31748932
https://pubmed.ncbi.nlm.nih.gov/31748932