Výsledky vyhledávání - "Esther Breij"

Akademický článek

813 Combination of HexaBody-CD27 with PD-(L)1 blockade potentiates single-agent activity leading to enhanced human T-cell effector functions in vitro

Autor: Jordan Blum, Alexander Muik, Isil Altintas, Friederike Gieseke, Aras Toker, Esther Breij, Tahamtan Ahmadi, Ugur Sahin, Kristel Kemper, Oezlem Tuereci, Kristina Nuermberger, Sina Fellermeier-Kopf, Andrea Imle, Anna-Lena Krause, Lidia Daszkiewicz

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

Externí odkaz: https://doaj.org/article/5b2dfbe7a11a49c1a72650313cf5a53d

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Akademický článek

P816: PHARMACODYNAMIC ACTIVITY OF GEN3014 (HEXABODY-CD38) IN PATIENTS WITH MULTIPLE MYELOMA SUPPORTS ENHANCED COMPLEMENT DEPENDENT CYTOTOXICITY OF GEN3014 COMPARED TO DARATUMUMAB

Autor: Ida H. Hiemstra, Kim Santegoets, Maarten Janmaat, Wessel Ten Hagen, Rosanna Sanchez, Lauren Brady, Sieto Bosgra, Marije Overdijk, Jenny Chen, Katrine Fladeland Iversen, Torben Plesner, Esther Breij

Publikováno v: HemaSphere, Vol 7, p e008261b (2023)

Externí odkaz: https://doaj.org/article/4f633667bf9e4dc6b0f47f3a8fb66a88

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Akademický článek

863 In vitro and in vivo studies establish DuoBody®-CD3xB7H4 as a novel drug candidate for the treatment of solid cancers

Autor: Kate Sasser, Esther Breij, Mischa Houtkamp, Stefanie De Poot, Louise Koopman, Laura Smits-de Vries, Frederikke Lihme Egerod, Sebastiaan Wubben, Madelon Paauwe, Edward van den Brink, Andrea Gorlani, Dennis Verzijl

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)

Externí odkaz: https://doaj.org/article/d407118526334d7e82d8f9c77b1ec4b4

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Akademický článek

889 DuoBody®-CD3x5T4 induces efficient T-cell activation and killing of patient-derived head and neck cancer cells in vitro and ex vivo

Autor: Patrick Franken, Esther Breij, Kristel Kemper, Rieneke van de Ven, Sonja Ganzevles, Myrthe Veth, Ruud Brakenhoff

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)

Externí odkaz: https://doaj.org/article/bdf003f55a9748d692058832d62544f2

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Akademický článek

561 DuoBody®-PD-L1×4–1BB (GEN1046) induces superior immune-cell activation, cytokine production and cytotoxicity by combining PD-L1 blockade with conditional 4–1BB co-stimulation

Autor: Maria Jure-Kunkel, Rachelle Kosoff, Mark Fereshteh, Alexander Muik, Isil Altintas, Friederike Gieseke, Kristina Schödel, Theodora Salcedo, Saskia Burm, Aras Toker, Lena Kranz, Mathias Vormehr, David Eisel, Özlem Türeci, Esther Breij, Tahamtan Ahmadi, Ugur Sahin

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)

Externí odkaz: https://doaj.org/article/eea14f7713674c8fb51f93a571e8bfb1

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1351 Preclinical mechanism of action and pharmacodynamic biomarker studies of DuoBody®-CD3xB7H4 in solid cancer models

Autor: Louise Koopman, Madelon Paauwe, Laura Smits-de Vries, Frosso Karaiskaki, Marcel Brandhorst, Patrick Franken, Theo Plantinga, Stefanie De Poot, Mischa Houtkamp, Kate Sasser, Esther Breij

Publikováno v: Regular and Young Investigator Award Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2dff5ff32d6079e57e79436c99c73aa4
https://doi.org/10.1136/jitc-2022-sitc2022.1351

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1070 HexaBody-CD27 enhances T-cell activation, proliferation, cytokine secretion and cytotoxic activity independently of Fc gamma receptor-mediated crosslinking

Publikováno v: Regular and Young Investigator Award Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::46da6e1d93549fd2256407ac11968209
https://doi.org/10.1136/jitc-2022-sitc2022.1070

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