Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Esther Bloem"'
Autor:
Brian Lauritzen, Mads Bjelke, Olle Björkdahl, Esther Bloem, Kevin Keane, Marianne Kjalke, Marie Rossen, Solvej Lund Lippert, Karin Nana Weldingh, Mikala Skydsgaard, Stine Kjellev
Publikováno v:
Journal of Thrombosis and Haemostasis. 20:1312-1324
Mim8 is a novel, next-generation factor VIIIa mimetic in development for subcutaneous prophylactic treatment of patients with hemophilia A with and without inhibitors. In vitro and in vivo models indicate that Mim8 has a distinct hemostatic potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a297c1a3dbd1aa78cc4af6bf7161de
https://doi.org/10.1111/jth.15682
https://doi.org/10.1111/jth.15682
Norwegian agriculture is challenged by increased production demand and climate change while being faced with tight restrictions to its environmental impact. Due to climate change, an increase in extreme weather events is expected. High intensity rain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eea5b6eb35661c6fca5f5e4ba33fef3e
https://doi.org/10.5194/egusphere-egu23-16030
https://doi.org/10.5194/egusphere-egu23-16030
Autor:
Eduard H.T.M. Ebberink, Eveline A.M. Bouwens, Esther Bloem, Mariëtte Boon-Spijker, Maartje van den Biggelaar, Jan Voorberg, Alexander B. Meijer, Koen Mertens
Publikováno v:
Haematologica, Vol 102, Iss 4 (2017)
Factor VIII C-domains are believed to have specific functions in cofactor activity and in interactions with von Willebrand factor. We have previously shown that factor VIII is co-targeted with von Willebrand factor to the Weibel-Palade bodies in bloo
Externí odkaz:
https://doaj.org/article/249218b0d5384c50aed37bce608c5f9a
Autor:
Gabi Overgaard Øvlisen, Peter Thygesen, Karin Nana Weldingh, Esther Bloem, Søren Skov, Kasper Almholt, Karin Maria Lövgren, Carsten Dan Ley, Thomas Lindebo Holm
Publikováno v:
Haemophilia : the official journal of the World Federation of HemophiliaREFERENCES. 28(4)
Immunogenicity causing development of anti-drug antibodies (ADAs) are major challenges in the treatment of haemophilia, as well as other diseases where proteins are used for treatment. Furthermore, it is a complication for preclinical testing of such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a04c98f9801912095782a503decf59a
https://pubmed.ncbi.nlm.nih.gov/35467059
https://pubmed.ncbi.nlm.nih.gov/35467059
Autor:
Nicoletta Sorvillo, Robin B. Hartholt, Esther Bloem, Magdalena Sedek, Anja ten Brinke, Carmen van der Zwaan, Floris P. van Alphen, Alexander B. Meijer, Jan Voorberg
Publikováno v:
Haematologica, Vol 101, Iss 3 (2016)
It has been proposed that von Willebrand factor might affect factor VIII immunogenicity by reducing factor VIII uptake by antigen presenting cells. Here we investigate the interaction of recombinant von Willebrand factor with immature monocyte-derive
Externí odkaz:
https://doaj.org/article/b28ed143071e4b9a842230f9a440e7b1
Publikováno v:
CATENA
The occurrence of freeze–thaw cycles modifies water infiltration processes and surface runoff generation. Related processes are complex and are not yet fully investigated at field scale. While local weather conditions and soil management practices
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5cfad4b8139975e4c43d379c6f6914
https://hdl.handle.net/11250/3020025
https://hdl.handle.net/11250/3020025
Publikováno v:
Journal of Contaminant Hydrology. 221:1-10
Degradation of organic chemicals in natural soils depends on oxidation-reduction conditions. To protect our groundwater resources we need to understand the degradation processes under anaerobic conditions . Available iron and manganese oxides are use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17ebfc37c9c6a2d73863664034ae918
https://doi.org/10.1016/j.jconhyd.2018.12.002
https://doi.org/10.1016/j.jconhyd.2018.12.002
Assessing redox conditions in soil and groundwater is challenging because redox reactions are oxygen sensitive, hence, destructive sampling methods may provide contact with air and influence the redox state. Furthermore, commonly used redox potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeff99aac82badb21d4c75b632671638
https://doi.org/10.1016/j.jconhyd.2019.103517
https://doi.org/10.1016/j.jconhyd.2019.103517
Publikováno v:
Lancaster University-Pure
Summary Common redox potential sensors provide point measurements and are error prone. Destructive sampling can cause contact with air which will influence the redox state. Hence, assessing redox conditions in soil is challenging. Redox sensitive rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f18c792e2e2034f50229adc53d18ce
https://doi.org/10.3997/2214-4609.201901661
https://doi.org/10.3997/2214-4609.201901661
Autor:
Emil Egecioglu, Majken Dalgaard, Marie Østergaard Pedersen, Birgitte Schjellerup Wulff, Mikala Skydsgaard, Alan Broadmeadow, Clare J. Chesher, Ridhirama Bhuwania, Esther Bloem, Emma Moore, Manuel Tena-Sempere, Hannah Williams, Lærke W. Andersen, Pia Søndergaard Galle, Florian Bolze, Johan F. Paulsson
Publikováno v:
Toxicology and Applied Pharmacology. 404:115152
Energy metabolism and reproduction are closely linked and reciprocally regulated. The detrimental effect of underweight on reproduction complicates the safety evaluation of anti-obesity drugs, making it challenging to distinguish pathological changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711c0139312e6bed6d38c6b05112dbcd
https://doi.org/10.1016/j.taap.2020.115152
https://doi.org/10.1016/j.taap.2020.115152