Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Esther Bettiol"'
Autor:
Alison Luckey, Emilie Alirol, Sophie Delhomme, John O'Donnell, Esther Bettiol, John Mueller, Seamus O'Brien, Jean‐Yves Gillon
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 5, Pp 770-780 (2023)
Abstract Gonorrhea is a sexually transmitted infection for which antibiotic treatment options have declined due to increasing antibiotic resistance. Zoliflodacin, an investigational oral spiropyrimidinetrione antibiotic with activity against Neisseri
Externí odkaz:
https://doaj.org/article/06e6f3f90fcb4202b94a93a19b09741c
Autor:
Esther Bettiol, Stephan Harbarth
Publikováno v:
Swiss Medical Weekly, Vol 145, Iss 3132 (2015)
Since 2010, awareness of the global threat caused by antimicrobial resistance (AMR) has risen considerably and multiple policy and research initiatives have been implemented. Research and development (R&D) of much-needed new antibiotics active agains
Externí odkaz:
https://doaj.org/article/63750bfd33014a3681c48b99f456ec7d
Autor:
Esther Bettiol, Marie Samanovic, Andrew S Murkin, Jayne Raper, Frederick Buckner, Ana Rodriguez
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 3, Iss 2, p e384 (2009)
The development of new drugs against Chagas disease is a priority since the currently available medicines have toxic effects, partial efficacy and are targeted against the acute phase of disease. At present, there is no drug to treat the chronic stag
Externí odkaz:
https://doaj.org/article/caa3f56a0453461daa6b1298a3f4130c
Autor:
Jamie M Orengo, James E Evans, Esther Bettiol, Aleksandra Leliwa-Sytek, Karen Day, Ana Rodriguez
Publikováno v:
PLoS Pathogens, Vol 4, Iss 3, p e1000013 (2008)
Infection of erythrocytes with the Plasmodium parasite causes the pathologies associated with malaria, which result in at least one million deaths annually. The rupture of infected erythrocytes triggers an inflammatory response, which is induced by p
Externí odkaz:
https://doaj.org/article/7e0e8b8d330e4ff0b0a34f0222d311f5
Autor:
Takeshi Ono, Laura Cabrita-Santos, Ricardo Leitao, Esther Bettiol, Lisa A Purcell, Olga Diaz-Pulido, Lucy B Andrews, Takushi Tadakuma, Purnima Bhanot, Maria M Mota, Ana Rodriguez
Publikováno v:
PLoS Pathogens, Vol 4, Iss 2, p e1000008 (2008)
Malaria starts with the infection of the liver of the host by Plasmodium sporozoites, the parasite form transmitted by infected mosquitoes. Sporozoites migrate through several hepatocytes by breaching their plasma membranes before finally infecting o
Externí odkaz:
https://doaj.org/article/ea175e31ad4b470faeb9247f112b5664
Autor:
David Wilson, Stéphan Juergen Harbarth, Stavros Nikolakopoulos, Emmanuel Weiss, Harriet Sommer, Marlieke E. A. de Kraker, Jean-François Timsit, Martin Wolkewitz, Esther Bettiol
Publikováno v:
Intensive Care Medicine
Intensive Care Medicine, 43(7), 1002. Springer Verlag
Intensive Care Medicine, Vol. 43, No 7 (2017) pp. 1002-1012
Intensive Care Medicine, 43(7), 1002. Springer Verlag
Intensive Care Medicine, Vol. 43, No 7 (2017) pp. 1002-1012
Purpose: In this era of rising antimicrobial resistance, slowly refilling antibiotic development pipelines, and an aging population, we need to ensure that randomized clinical trials (RCTs) determine the added benefit of new antibiotic agents effecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102967e2664b73cd0328eca4c08dc7e3
http://europepmc.org/articles/PMC5487537
http://europepmc.org/articles/PMC5487537
Publikováno v:
The Journal of Law, Medicine & Ethics, Vol. 46, No 1_suppl (2018) pp. 5-8
Global discussions are ongoing on how to stimulate antibiotic research and development in order to provide patients with new antibiotics able to address the challenges of antimicrobial resistance. In this supplement, we present nine articles derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef064cdd134d5d3e5bbf832499fa19f6
https://archive-ouverte.unige.ch/unige:110978
https://archive-ouverte.unige.ch/unige:110978
Publikováno v:
Antimicrobial Agents and Chemotherapy, Vol. 59, No 7 (2015) pp. 3695-99
As the number of antibacterial medicines in the pipeline remains low, we anonymously surveyed pharmaceutical industry professionals on challenges and solutions for clinical development of these agents. Challenges were reported primarily as financial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249efb6bbe54fa3435601df6887ed22d
https://doi.org/10.1128/aac.00638-15
https://doi.org/10.1128/aac.00638-15
Autor:
Afksendyios Kalangos, François Herrmann, Qing He, Marisa Jaconi, Michel Dubois-Dauphin, Esther Bettiol, Pedro T. Trindade, Michael Stumm, Jian Li, Denis R. Morel, Prisca Zammaretti
Publikováno v:
Journal of Cellular and Molecular Medicine
Journal of Cellular and Molecular Medicine, Vol. 13, No 1 (2009) pp. 188-201
Journal of Cellular and Molecular Medicine, Vol. 13, No 1 (2009) pp. 188-201
It has recently been suggested that the infarcted rat heart microenvironment could direct pluripotent mouse embryonic stem cells to differentiate into cardiomyocytes through an in situ paracrine action. To investigate whether the heart can function a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df9ca1dec7a66a6579122be9fff18f1
https://doi.org/10.1111/j.1582-4934.2008.00323.x
https://doi.org/10.1111/j.1582-4934.2008.00323.x
Autor:
Christine Chaponnier, Sandy Kampf, Karl-Heinz Krause, Michael Stouffs, Sophie Clément, Marisa Jaconi, Esther Bettiol
Publikováno v:
Journal of Cell Science, Vol. 120, No Pt 2 (2007) pp. 229-238
Three alpha-muscle actin isoforms are sequentially expressed during in vivo cardiac development. alpha-Smooth muscle actin is first and transiently expressed, followed by alpha-skeletal and finally alpha-cardiac actin. The significance of these trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a387bc4ef3e0d216931fdee9df9b04e8
https://doi.org/10.1242/jcs.03340
https://doi.org/10.1242/jcs.03340