Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Esther Baena"'
Autor:
Pedro Oliveira, Robert G Bristow, Ashwin Sachdeva, Noel Clarke, Hitesh Mistry, Amin Ali, Thiraviyam Elumalai, BhanuPrasad Venkatesulu, Lauren Hekman, Esther Baena
Publikováno v:
BMJ Oncology, Vol 3, Iss 1 (2024)
Objective To assess pathological characteristics, clinical features and outcomes of patients diagnosed with peripheral zone (PZ) and transition zone (TZ) prostate cancer after prostatectomy.Methods and analysis We systematically reviewed PubMed, EMBA
Externí odkaz:
https://doaj.org/article/d688267134774f6b9052fd06bfbc51fb
Autor:
Ivana Steiner, Teresita del N.J. Flores-Tellez, Renaud Mevel, Amin Ali, Pengbo Wang, Pieta Schofield, Caron Behan, Nicholas Forsythe, Garry Ashton, Catherine Taylor, Ian G. Mills, Pedro Oliveira, Simon S. McDade, Dietmar M. Zaiss, Ananya Choudhury, Georges Lacaud, Esther Baena
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112377- (2023)
Summary: The emergence of castration-resistant prostate cancer remains an area of unmet clinical need. We recently identified a subpopulation of normal prostate progenitor cells, characterized by an intrinsic resistance to androgen deprivation and ex
Externí odkaz:
https://doaj.org/article/ea2b525372434ee5b0059bdaa9e2fe69
Autor:
Ana Villegas-Mendez, Nicholas Stafford, Michael J. Haley, Normalita Eka Pravitasari, Florence Baudoin, Adnan Ali, Puji Budi Setia Asih, Josephine E. Siregar, Esther Baena, Din Syafruddin, Kevin N. Couper, Delvac Oceandy
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-16 (2021)
Abstract Background Recent genome wide analysis studies have identified a strong association between single nucleotide variations within the human ATP2B4 gene and susceptibility to severe malaria. The ATP2B4 gene encodes the plasma membrane calcium A
Externí odkaz:
https://doaj.org/article/0193d8e284dd47609fc0be6ba801edee
Autor:
Renaud Mevel, Ivana Steiner, Susan Mason, Laura CA Galbraith, Rahima Patel, Muhammad ZH Fadlullah, Imran Ahmad, Hing Y Leung, Pedro Oliveira, Karen Blyth, Esther Baena, Georges Lacaud
Publikováno v:
eLife, Vol 9 (2020)
The characterization of prostate epithelial hierarchy and lineage heterogeneity is critical to understand its regenerative properties and malignancies. Here, we report that the transcription factor RUNX1 marks a specific subpopulation of proximal lum
Externí odkaz:
https://doaj.org/article/5138643e69d14f3ba32afe32b89a6553
Autor:
João D. Barros-Silva, Douglas E. Linn, Ivana Steiner, Guoji Guo, Adnan Ali, Hubert Pakula, Garry Ashton, Isabel Peset, Michael Brown, Noel W. Clarke, Roderick T. Bronson, Guo-Cheng Yuan, Stuart H. Orkin, Zhe Li, Esther Baena
Publikováno v:
Cell Reports, Vol 25, Iss 12, Pp 3504-3518.e6 (2018)
Summary: The exact identity of castrate-resistant (CR) cells and their relation to CR prostate cancer (CRPC) is unresolved. We use single-cell gene profiling to analyze the molecular heterogeneity in basal and luminal compartments. Within the luminal
Externí odkaz:
https://doaj.org/article/2f22d3716c8c468ba350775bbac057b6
Autor:
Pedro Oliveira, Alexander Du Feu, Robert G. Bristow, Esther Baena, Ananya Choudhury, Amin Ali
Publikováno v:
Ali, A, Du Feu, A, Oliveira, P, Choudhury, A, Bristow, R G & Baena, E 2022, ' Prostate zones and cancer: lost in transition? ', Nature Reviews. Urology . https://doi.org/10.1038/s41585-021-00524-7
Localized prostate cancer shows great clinical, genetic and environmental heterogeneity; however, prostate cancer treatment is currently guided solely by clinical staging, serum PSA levels and histology. Increasingly, the roles of differential genomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6975ad7d8814e9a6c9e504d153676cc
https://doi.org/10.1038/s41585-021-00524-7
https://doi.org/10.1038/s41585-021-00524-7
Autor:
Esther Baena, Andrew J. Finch
Publikováno v:
Cancer Discov
Mitochondria provide the front-line of defense against the tumor-promoting effects of oxidative stress. Here we show that the prostate-specific homeoprotein, NKX3.1, suppresses prostate cancer initiation by protecting mitochondria from oxidative stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78fc8bf1e4e2488604c619cd4693cc5a
https://doi.org/10.1158/2159-8290.cd-21-0861
https://doi.org/10.1158/2159-8290.cd-21-0861
Autor:
Amin Ali, Esther Baena
Publikováno v:
European Urology. 81:456-457
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::829d5430b561dc0cfa5b50ad3724840b
https://doi.org/10.1016/j.eururo.2022.02.004
https://doi.org/10.1016/j.eururo.2022.02.004
Autor:
Puji Budi Setia Asih, Delvac Oceandy, Josephine E. Siregar, Nicholas Stafford, Ana Villegas-Mendez, Michael J. Haley, Kevin N. Couper, Florence Baudoin, Din Syafruddin, Adnan Ali, Esther Baena, Normalita Eka Pravitasari
Publikováno v:
Malaria Journal
Malaria Journal, Vol 20, Iss 1, Pp 1-16 (2021)
Malaria Journal, Vol 20, Iss 1, Pp 1-16 (2021)
Background Recent genome wide analysis studies have identified a strong association between single nucleotide variations within the human ATP2B4 gene and susceptibility to severe malaria. The ATP2B4 gene encodes the plasma membrane calcium ATPase 4 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae4d5a42b19e1e0f35edef44f5c176d
http://europepmc.org/articles/PMC8252299
http://europepmc.org/articles/PMC8252299
Publikováno v:
Cancer letters. 524
Tumor heterogeneity plays a key role in prostate cancer prognosis, therapy selection, relapse, and acquisition of treatment resistance. Prostate cancer presents a heterogeneous diversity at inter- and intra-tumor and inter-patient levels which are in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346a3b61703eb28c5beeed5420eb4e65
https://pubmed.ncbi.nlm.nih.gov/34688843
https://pubmed.ncbi.nlm.nih.gov/34688843