Intraperitoneal irinotecan with concomitant FOLFOX and bevacizumab for patients with unresectable colorectal peritoneal metastases: protocol of the multicentre, open-label, phase II, INTERACT-II trial

Autor: Jacobus W A Burger, Cornelis Verhoef, Eva V E Madsen, Robin J Lurvink, Joost Nederend, Onno Kranenburg, Geert-Jan M Creemers, Simon W Nienhuijs, Alexandra R M Brandt-Kerkhof, Esther van Meerten, Stijn L W Koolen, Ignace H J T de Hingh, Ron H J Mathijssen, Niels A D Guchelaar, Vincent C J van de Vlasakker, Teun B M van den Heuvel, Ramon J F Bax, Irene E G van Hellemond

Publikováno v: BMJ Open, Vol 14, Iss 1 (2024)

Introduction The peritoneum is the second most affected organ for the dissemination of colorectal cancer (CRC). Patients with colorectal peritoneal metastases (CPM) face a poor prognosis, despite the majority of patients being treated with palliative

Externí odkaz: https://doaj.org/article/877cd15e67af4bc4a42c3f8c7e9ff4ae

Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: protocol of a multicentre, open-label, parallel-group, phase II-III, randomised, superiority study (CAIRO6)

Autor: Koen P. Rovers, Checca Bakkers, Geert A. A. M. Simkens, Jacobus W. A. Burger, Simon W. Nienhuijs, Geert-Jan M. Creemers, Anna M. J. Thijs, Alexandra R. M. Brandt-Kerkhof, Eva V. E. Madsen, Ninos Ayez, Nadine L. de Boer, Esther van Meerten, Jurriaan B. Tuynman, Miranda Kusters, Nina R. Sluiter, Henk M. W. Verheul, Hans J. van der Vliet, Marinus J. Wiezer, Djamila Boerma, Emma C. E. Wassenaar, Maartje Los, Cornelis B. Hunting, Arend G. J. Aalbers, Niels F. M. Kok, Koert F. D. Kuhlmann, Henk Boot, Myriam Chalabi, Schelto Kruijff, Lukas B. Been, Robert J. van Ginkel, Derk Jan A. de Groot, Rudolf S. N. Fehrmann, Johannes H. W. de Wilt, Andreas J. A. Bremers, Philip R. de Reuver, Sandra A. Radema, Karin H. Herbschleb, Wilhelmina M. U. van Grevenstein, Arjen J. Witkamp, Miriam Koopman, Nadia Haj Mohammad, Eino B. van Duyn, Walter J. B. Mastboom, Leonie J. M. Mekenkamp, Joost Nederend, Max J. Lahaye, Petur Snaebjornsson, Cornelis Verhoef, Hanneke W. M. van Laarhoven, Aeilko H. Zwinderman, Jeanette M. Bouma, Onno Kranenburg, Iris van ‘t Erve, Remond J. A. Fijneman, Marcel G. W. Dijkgraaf, Patrick H. J. Hemmer, Cornelis J. A. Punt, Pieter J. Tanis, Ignace H. J. T. de Hingh, Dutch Peritoneal Oncology Group (DPOG), Dutch Colorectal Cancer Group (DCCG)

Publikováno v: BMC Cancer, Vol 19, Iss 1, Pp 1-15 (2019)

Abstract Background Upfront cytoreductive surgery with HIPEC (CRS-HIPEC) is the standard treatment for isolated resectable colorectal peritoneal metastases (PM) in the Netherlands. This study investigates whether addition of perioperative systemic th

Externí odkaz: https://doaj.org/article/0eae7e00e09f44039f07a47639a0e680

Post radiation mucosal ulcer risk after a hypofractionated stereotactic boost and conventional fractionated radiotherapy for oropharyngeal carcinoma

Autor: Gerda M. Verduijn, Steven F. Petit, Iris Lauwers, Yvette van Norden, Nienke D. Sijtsema, Aniel Sewnaik, Hetty Mast, Marta Capala, Remi Nout, Sarah Baker, Esther van Meerten, Mischa S. Hoogeman, Aad van der Lugt, Wilma D. Heemsbergen

Publikováno v: Acta Oncologica, 62(1), 40-47. Informa Healthcare

Background/purpose: Post radiation mucosal ulcers (PRMU) after treatment for oropharyngeal squamous cell carcinoma (OPSCC) can have a huge negative impact on patients’ quality of life, but little is known concerning risk factors and the impact of f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abff01a7156ca5ae5844436ebf328a2e
http://www.scopus.com/inward/record.url?scp=85145489803&partnerID=8YFLogxK

Comparison of toxicity and effectiveness between fixed-dose and body surface area-based dose capecitabine

Autor: Femke M. de Man, G.D. Marijn Veerman, Esther Oomen-de Hoop, Maarten J. Deenen, Didier Meulendijks, Caroline M.P.W. Mandigers, Marcel Soesan, Jan H.M. Schellens, Esther van Meerten, Teun van Gelder, Ron H.J. Mathijssen

Publikováno v: Therapeutic Advances in Medical Oncology, Vol 11 (2019)

Background: Capecitabine is generally dosed based on body surface area (BSA). This dosing strategy has several limitations; however, evidence for alternative strategies is lacking. Therefore, we analyzed the toxicity and effectiveness of fixed-dose c

Externí odkaz: https://doaj.org/article/83660daccf0142229ea5b2375699afac

Quality of Life and Survival of Metastatic Colorectal Cancer Patients Treated With Trifluridine-Tipiracil (QUALITAS)

Autor: Patricia A.H. Hamers, Geraldine R. Vink, Marloes A.G. Elferink, Rebecca K. Stellato, Willemieke P.M. Dijksterhuis, Cornelis J.A. Punt, Miriam Koopman, Anne M. May, Laurens V. Beerepoot, Geert-Jan Creemers, Hester van Cruijsen, Jan Willem B. de Groot, Henk K. van Halteren, Helgi H. Helgason, Mathijs P. Hendriks, Ronald Hoekstra, Lieke H. van Huis-Tanja, Ellen Kapiteijn, Maartje Los, Esther van Meerten, Natascha A.J.B. Peters, Johannes F.M. Pruijt, Patricia Quarles van Ufford-Mannesse, Mark P.S. Sie, Dirkje W. Sommeijer, Leontine E.A.M.M. Spierings, Frederiek Terheggen, Manuel L.R. Tjin-A-Ton, Liselot B.J. Valkenburg-van Iersel, Theo van Voorthuizen, Judith de Vos-Geelen, Annelie J.E. Vulink, Agnès J van de Wouw

Publikováno v: Clinical Colorectal Cancer, 21(2), 154-166. Elsevier
on behalf of the QUALITAS study group 2022, ' Quality of Life and Survival of Metastatic Colorectal Cancer Patients Treated With Trifluridine-Tipiracil (QUALITAS) ', Clinical Colorectal Cancer, vol. 21, no. 2, pp. 154-166 . https://doi.org/10.1016/j.clcc.2022.03.002
Clinical colorectal cancer, 21(2), 154-166. Elsevier
Clinical Colorectal Cancer, 21(2), 154-166. CIG Media Group, L.P.

INTRODUCTION: The RECOURSE trial demonstrated a modest benefit in overall survival (OS) for trifluridine/tipiracil (FTD/TPI) versus placebo in pretreated metastatic colorectal cancer (mCRC) patients. Unfortunately, quality of life (QoL) was not asses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8074c3f95e3d5c5234a7fcca8125ae85
https://doi.org/10.1016/j.clcc.2022.03.002