Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Esther, Mahabir"'
Autor:
Jaco Selle, Katharina Dinger, Vanessa Jentgen, Daniela Zanetti, Johannes Will, Theodoros Georgomanolis, Christina Vohlen, Rebecca Wilke, Baktybek Kojonazarov, Oleksiy Klymenko, Jasmine Mohr, Silke v. Koningsbruggen-Rietschel, Christopher J. Rhodes, Anna Ulrich, Dharmesh Hirani, Tim Nestler, Margarete Odenthal, Esther Mahabir, Sreenath Nayakanti, Swati Dabral, Thomas Wunderlich, James Priest, Werner Seeger, Jörg Dötsch, Soni S. Pullamsetti, Miguel A. Alejandre Alcazar
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
This study shows that maternal and perinatal obesity cause bronchial and vascular smooth muscle cell proliferation through an IL-6-FoxO1 axis, and favor thereby the emergence of bronchial obstruction and pulmonary hypertension later in life.
Externí odkaz:
https://doaj.org/article/b4419ac41c554af68c918ae4ee7c5d81
Autor:
Nina Ferrari, Nikola Schmidt, Inga Bae-Gartz, Christina Vohlen, Miguel A Alejandre Alcazar, Konrad Brockmeier, Jörg Dötsch, Esther Mahabir, Christine Joisten
Publikováno v:
Children, Vol 10, Iss 11, p 1797 (2023)
The benefits of maternal physical activity during pregnancy are well documented, but long-term effects on the child have been less studied. Therefore, we conducted a pilot follow-up study of a lifestyle intervention during pregnancy that aimed to inv
Externí odkaz:
https://doaj.org/article/9508b4b9de16417a84270c45bbc522e3
Autor:
Xiaojie Yu, Natalia Elfimova, Marion Müller, Daniel Bachurski, Ulrike Koitzsch, Uta Drebber, Esther Mahabir, Hinrich P. Hansen, Scott L. Friedman, Sabine Klein, Hans Peter Dienes, Marianna Hösel, Reinhard Buettner, Jonel Trebicka, Vangelis Kondylis, Inge Mannaerts, Margarete Odenthal
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 6, Pp 1701-1716 (2022)
Background & Aims: Liver fibrosis arises from long-term chronic liver injury, accompanied by an accelerated wound healing response with interstitial accumulation of extracellular matrix (ECM). Activated hepatic stellate cells (HSC) are the main sourc
Externí odkaz:
https://doaj.org/article/4c80ebac8aa7408c99ac2c230a18d43f
Autor:
Giuliano Crispatzu, Rizwan Rehimi, Tomas Pachano, Tore Bleckwehl, Sara Cruz-Molina, Cally Xiao, Esther Mahabir, Hisham Bazzi, Alvaro Rada-Iglesias
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Poised enhancers (PEs) in embryonic stem cells have accessible chromatin, are bound by repressive Polycomb Group proteins, and interact with their targets prior to activation. However, whether this is recapitulated in vivo is unknown. Here the author
Externí odkaz:
https://doaj.org/article/63558f435dcb4a0498df455068ac08d2
Autor:
Nina Ferrari, Laura Schmitz, Nikola Schmidt, Esther Mahabir, Patricia Van de Vondel, Waltraut M. Merz, Walter Lehmacher, Stephanie Stock, Konrad Brockmeier, Regina Ensenauer, Tanja Fehm, Christine Joisten
Publikováno v:
BMC Sports Science, Medicine and Rehabilitation, Vol 12, Iss 1, Pp 1-10 (2020)
Abstract Background The prevalence of obesity in childhood is increasing worldwide and may be affected by genetic factors and the lifestyle (exercise, nutrition behavior) of expectant parents. Lifestyle factors affect adipokines, namely leptin, resis
Externí odkaz:
https://doaj.org/article/f720505df1d3411da076e4b17045950c
Autor:
Nina Ferrari, Nikola Schmidt, Lisa Schmidt, Waltraut M. Merz, Konrad Brockmeier, Jörg Dötsch, Inga Bae-Gartz, Esther Mahabir, Christine Joisten
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 447 (2023)
Lifestyle during pregnancy impacts the health of the mother and child. However, the extent to which physical activity affects maternal biomarkers and factors that might influence birth weight remains unclear. We analysed data from two lifestyle inter
Externí odkaz:
https://doaj.org/article/4218e11a2dd6483289372638d44c6206
Autor:
Jan Simon Scharrenberg, Ayla Yagdiran, Julia Brinkmann, Maik Brune, Jan Siewe, Norma Jung, Esther Mahabir
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 14, Iss 1, Pp 1-13 (2019)
Abstract Background There is still a challenge in discriminating between vertebral osteomyelitis and degenerative diseases of the spine. To this end, we determined the suitability of soluble urokinase-type plasminogen activator receptor (suPAR) and c
Externí odkaz:
https://doaj.org/article/1a75519498674fed91065ca6649a6163
Autor:
Laura Schmitz, Nina Ferrari, Andreas Schwiertz, Kerstin Rusch, Ulrich Woestmann, Esther Mahabir, Christine Graf
Publikováno v:
Pilot and Feasibility Studies, Vol 5, Iss 1, Pp 1-8 (2019)
Abstract Background The human microbiota has a broad range of functions contributing to metabolic processes and the activities of our immune system. Its influence on health, well-being and chronic diseases are discussed in various studies. The intest
Externí odkaz:
https://doaj.org/article/4555b3c7a94f432893edb029bde33697
Autor:
Marcello Raspa, Renata Paoletti, Manon Peltier, Mohamed Majjouti, Michele Protti, Laura Mercolini, Esther Mahabir, Ferdinando Scavizzi
Publikováno v:
Animals, Vol 12, Iss 11, p 1350 (2022)
D-Aspartate (D-Asp) treatment improved the fertility of young male C57BL/6N mice in vivo revealing a direct role on capacitation, acrosome reaction, and fertility in vitro in young males only. We investigated whether the positive effect of D-Asp on f
Externí odkaz:
https://doaj.org/article/b3a925c704c241acb723f2e1f3786435
Autor:
Iris F. Macheleidt, Priya S. Dalvi, So‐Young Lim, Sonja Meemboor, Lydia Meder, Olivia Käsgen, Marion Müller, Karolin Kleemann, Lingyu Wang, Peter Nürnberg, Vanessa Rüsseler, Stephan C. Schäfer, Esther Mahabir, Reinhard Büttner, Margarete Odenthal
Publikováno v:
Molecular Oncology, Vol 12, Iss 11, Pp 1965-1979 (2018)
Lung adenocarcinoma (LUAD) is the most prevalent subtype of non‐small cell lung cancer. Despite the development of novel targeted and immune therapies, the 5‐year survival rate is still only 21%, indicating the need for more efficient treatment r
Externí odkaz:
https://doaj.org/article/01479b8ac03b4b2698e864566fcccc7f