Characterization of Mesothelin Glycosylation in Pancreatic Cancer: Decreased Core Fucosylated Glycoforms in Pancreatic Cancer Patients’ Sera

Autor: Adrià Duran, Pedro E. Guerrero, Maria Rosa Ortiz, Dúnia Pérez del Campo, Ernesto Castro, Adelaida Garcia-Velasco, Esther Fort, Rafael de Llorens, Radka Saldova, Esther Llop, Rosa Peracaula

Publikováno v: Biomedicines, Vol 10, Iss 8, p 1942 (2022)

Currently, there are no reliable biomarkers for the diagnosis of pancreatic cancer (PaC). Glycoproteomic approaches that analyze the glycan determinants on specific glycoproteins have proven useful to develop more specific cancer biomarkers than the

Externí odkaz: https://doaj.org/article/4f9c97c307a3403791b9747ea1669e8b

Proceedings of workshop: 'Neuroglycoproteins in health and disease', INNOGLY cost action

Autor: Esther Llop, Ana Ardá, Elsa Zacco, Roisin O’Flaherty, María-Salud García-Ayllón, Massimo Aureli, Moran Frenkel-Pinter, Celso A. Reis, Ole K. Greiner-Tollersrud, Inmaculada Cuchillo-Ibáñez

Publikováno v: Glycoconjugate Journal. 39:579-586

The Cost Action “Innovation with glycans: new frontiers from synthesis to new biological targets” (INNOGLY) hosted the Workshop “Neuroglycoproteins in health and disease”, in Alicante, Spain, on March 2022. This event brought together an euro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724405a1b40679ce18db4b6cf1987877
https://doi.org/10.1007/s10719-022-10078-4

Sialyltransferase Inhibitor Ac

Autor: Laura, Miró, Júlia, López, Pedro E, Guerrero, Neus, Martínez-Bosch, Noemí, Manero-Rupérez, Mireia, Moreno, M Rosa, Ortiz, Esther, Llop, Pilar, Navarro, Rosa, Peracaula

Publikováno v: Cancers. 14(24)

Hypersialylation is a feature of pancreatic ductal adenocarcinoma (PDA) and it has been related to tumor malignancy and immune suppression. In this work, we have evaluated the potential of the sialyltransferase inhibitor, Ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6e2bc030be058010abee66919c104e3d
https://pubmed.ncbi.nlm.nih.gov/36551619

Lectin Affinity Chromatography for the Discovery of Novel Cancer Glycobiomarkers: A Case Study with PSA Glycoforms and Prostate Cancer

Autor: Esther Llop, Rosa Peracaula

Publikováno v: Glycosylation ISBN: 9781071616840

Many clinical biomarkers in cancer are glycoproteins, but the majority of them only consider the protein levels. Indeed, only alfa-fetoprotein (AFP) in hepatocarcinoma and CA15-3 in breast cancer are clinically monitored for their glycoforms. Aberran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84f1f40a4d8c0e1fffbb76056f0eb6ba
https://doi.org/10.1007/978-1-0716-1685-7_15

Knockdown of α2,3-Sialyltransferases Impairs Pancreatic Cancer Cell Migration, Invasion and E-selectin-Dependent Adhesion

Autor: Esther Llop, Pilar Navarro, Pedro Enrique Guerrero, Anna Massaguer, Laura Miró, Bin Sheng Wong, Neus Martínez-Bosch, Rosa Peracaula, Rafael de Llorens, Konstantinos Konstantopoulos

Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 17
International Journal of Molecular Sciences, 2020, vol. 21, núm. 17, p. 6239
Articles publicats (D-B)
DUGiDocs – Universitat de Girona
instname
Digital.CSIC. Repositorio Institucional del CSIC
International Journal of Molecular Sciences, Vol 21, Iss 6239, p 6239 (2020)

Aberrant sialylation is frequently found in pancreatic ductal adenocarcinoma (PDA). &alpha
2,3-Sialyltransferases (&alpha
2,3-STs) ST3GAL3 and ST3GAL4 are overexpressed in PDA tissues and are responsible for increased biosynthesis of sialyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8a54ec4a02a44adbbe7ac26aa50908