Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Esther, Arman"'
Autor:
Moran Shalev, Sergey Kapishnikov, Esther Arman, Merle Stein, Isabelle Royal, Vlad Brumfeld, Ari Elson, Jan Tuckermann, Yael Cohen-Sharir
Publikováno v:
The FEBS Journal. 288:4702-4723
Bone-resorbing osteoclasts (OCLs) are multinucleated phagocytes, whose central roles in regulating bone formation and homeostasis are critical for normal health and development. OCLs are produced from precursor monocytes in a multistage process that
Autor:
Fadi Thalji, Jan Tuckermann, Merle Stein, Sabina Winograd-Katz, Benjamin Geiger, Esther Arman, Moien Kanaan, Moran Shalev, Ari Elson, Lee Roth, Nina Reuven, Ofra Golani, Maayan Barnea-Zohar
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Homozygosity for the R51Q mutation in sorting nexin 10 (SNX10) inactivates osteoclasts (OCLs) and induces autosomal recessive osteopetrosis in humans and in mice. We show here that the fusion of wild-type murine monocytes to form OCLs is highly regul
Autor:
Benjamin Geiger, Polina Stepensky, F Thalji, Maayan Barnea, Merle Stein, Moien Kanaan, Ari Elson, Jan Tuckermann, Hila Elinav, Sabina Winograd-Katz, Esther Arman, Moran Shalev, Ori Brenner
Publikováno v:
1. MuSkITYR Symposium.
Autor:
Lee, Roth, Jean, Wakim, Elad, Wasserman, Moran, Shalev, Esther, Arman, Merle, Stein, Vlad, Brumfeld, Cari A, Sagum, Mark T, Bedford, Jan, Tuckermann, Ari, Elson
Publikováno v:
Science signaling. 12(563)
Bone resorption by osteoclasts is essential for bone homeostasis. The kinase Src promotes osteoclast activity and is activated in osteoclasts by the receptor-type tyrosine phosphatase PTPROt. In other contexts, however, PTPROt can inhibit Src activit
Autor:
Mark T. Bedford, Ari Elson, Jan Tuckermann, Esther Arman, Moran Shalev, Jean Wakim, Merle Stein, Vlad Brumfeld, Cari A. Sagum, Elad Wasserman, Lee Roth
Publikováno v:
Science Signaling. 12
Bone resorption by osteoclasts is essential for bone homeostasis. The kinase Src promotes osteoclast activity and is activated in osteoclasts by the receptor-type tyrosine phosphatase PTPROt. In other contexts, however, PTPROt can inhibit Src activit
Autor:
Maayan Barnea-Zohar, Sabina Winograd-Katz, Polina Stepensky, Jennifer Gerstung, Fadi Thalji, Merle Stein, Hila Elinav, Jan Tuckermann, Moien Kanaan, Benjamin Geiger, Esther Arman, Ari Elson, Ori Brenner, Moran Shalev
Publikováno v:
Bone. 136:115360
The R51Q mutation in sorting nexin 10 (SNX10) was shown to cause a lethal genetic disease in humans, namely autosomal recessive osteopetrosis (ARO). We describe here the first R51Q SNX10 knock-in mouse model and show that mice homozygous for this mut
Autor:
Moran Shalev, Moien Kanaan, Sabina Winograd-Katz, Polina Stepensky, Ori Brenner, Fadi Thalji, Esther Arman, Merle Stein, Hila Elinav, Jan Tuckermann, Benjamin Geiger, Ari Elson, Maayan Barnea
SummaryThe molecular mechanisms that regulate fusion of monocytes into functional osteoclasts are virtually unknown. We describe a knock-in mouse model for the R51Q mutation in sorting nexin 10 (SNX10) that exhibits osteopetrosis and related symptoms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59af484292836e6ee7bdf864c69482c4
Autor:
Eszter Bakos, Matthias P. Kramer, Idit Shachar, Esther Arman, Shirly Becker-Herman, Ari Elson, Jean Wakim
Publikováno v:
Oncogene. 36(26)
The tyrosine phosphatase PTPROt is a suggested tumor suppressor (TS) in B-cell chronic lymphocytic leukemia (CLL), and its expression is reduced in this disease. In order to examine how reduced PTPROt expression affects CLL in vivo we induced CLL in
Publikováno v:
Development. 131:5277-5286
This study investigates the establishment of alternative cell fates during embryoid body differentiation when ES cells diverge into two epithelia simulating the pre-gastrulation endoderm and ectoderm. We report that endoderm differentiation and endod
Autor:
Ari Elson, Esther Arman, Eynat Finkelshtein, Jeroen den Hertog, Sutada Lotinun, Roland Baron, Einat Levy-Apter
Publikováno v:
Molecular Biology of the Cell, 25(11), 1808-18. American Society for Cell Biology
Molecular Biology of the Cell
Molecular Biology of the Cell
The closely related tyrosine phosphatases PTPa and PTPe fulfill distinct roles in osteoclasts. The various effects of each PTP on podosome organization in osteoclasts are caused by their distinct N-termini. The function of PTPe in these cells require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5bd25c6bf901494b8f8b736b30a2f6
https://pure.knaw.nl/portal/en/publications/73177a99-cf6a-4422-a964-1ea33cd24adf
https://pure.knaw.nl/portal/en/publications/73177a99-cf6a-4422-a964-1ea33cd24adf