Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Estevao Carlos Silva Barcelos"'
Autor:
Stefano Baldoni, Beatrice Del Papa, Filomena De Falco, Erica Dorillo, Carlo Sorrentino, Chiara Rompietti, Francesco Maria Adamo, Manuel Nogarotto, Debora Cecchini, Elena Mondani, Estevao Carlos Silva Barcelos, Lorenzo Moretti, Maria Grazia Mameli, Bianca Fabi, Daniele Sorcini, Arianna Stella, Raffaella Giancola, Francesco Guardalupi, Francesca Ulbar, Sara Plebani, Valerio Guarente, Emanuela Rosati, Marta Di Nicola, Michele Marchioni, Mauro Di Ianni, Paolo Sportoletti
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
NOTCH1 mutations and deregulated signal have been commonly found in chronic lymphocytic leukemia (CLL) patients. Whereas the impact of NOTCH1 mutations on clinical course of CLL has been widely studied, the prognostic role of NOTCH1 activation in CLL
Externí odkaz:
https://doaj.org/article/bf604ad42c61485b9c589e15303f6899
Autor:
Daniele Sorcini, Filomena De Falco, Marco Gargaro, Silvia Bozza, Valerio Guarente, Valeria Cardinali, Arianna Stella, Francesco Maria Adamo, Estevao Carlos Silva Barcelos, Chiara Rompietti, Erica Dorillo, Clelia Geraci, Angela Esposito, Roberta Arcaleni, Silvia Capoccia, Maria Grazia Mameli, Alessandro Graziani, Lorenzo Moretti, Alessandra Cipiciani, Carlo Riccardi, Antonella Mencacci, Francesca Fallarino, Emanuela Rosati, Paolo Sportoletti
Publikováno v:
British Journal of Haematology. 201:45-57
In chronic lymphocytic leukaemia (CLL) the efficacy of SARS-CoV-2 vaccination remains unclear as most studies have focused on humoral responses. Here we comprehensively examined humoral and cellular responses to vaccine in CLL patients. Seroconversio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c356fac7b0824446bb2966e1289a4ea
https://doi.org/10.1111/bjh.18602
https://doi.org/10.1111/bjh.18602
Autor:
Francesco Maria Adamo, Estevao Carlos Silva Barcelos, Filomena Falco, Erica Dorillo, Chiara Rompietti, Daniele Sorcini, Arianna Stella, Beatrice Del Papa, Stefano Baldoni, Angela Esposito, Clelia Geraci, Roberta Arcaleni, Chiara Pennetta, Francesco Ragonese, Lorenzo Moretti, Mariagrazia Mameli, Mauro Ianni, Emanuela Rosati, Bernard Fioretti, Paolo Sportoletti
Background Chronic lymphocytic leukemia (CLL) is an incurable disorder associated with alterations in several pathways essential for survival and proliferation. Despite the advances obtained in CLL therapy with the new target agents, in some cases re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42854700a1804eb917ccf37ee2596b9f
https://doi.org/10.21203/rs.3.rs-2897424/v1
https://doi.org/10.21203/rs.3.rs-2897424/v1
Autor:
Estevão Carlos Silva Barcelos, Michel Satya Naslavsky, Izadora Silveira Fernandes, Marilia Oliveira Scliar, Guilherme Lopes Yamamoto, Jaqueline Yu Ting Wang, Laís Bride, Valdemir Pereira de Sousa, Lucia Helena Sagrillo Pimassoni, Paolo Sportoletti, Flavia de Paula, Sandra Ventorin von Zeidler, Yeda Aparecida Oliveira Duarte, Maria Rita Passos-Bueno, Mayana Zatz, Flávia Imbroisi Valle Errera
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Excessive weight (overweight and obesity) is a common disorder involving genetic and environmental factors, associated with cardiovascular diseases, type-2 diabetes, and others. NOTCH1 is critical for the maintenance of stem cells and adult
Externí odkaz:
https://doaj.org/article/2fa406e763034efdb5b865ee2f956c05
Autor:
Giorgia Manni, Marco Gargaro, Doriana Ricciuti, Simona Fontana, Eleonora Padiglioni, Marco Cipolloni, Tommaso Mazza, Jessica Rosati, Alessandra di Veroli, Giulia Mencarelli, Benedetta Pieroni, Estevão Carlos Silva Barcelos, Giulia Scalisi, Francesco Sarnari, Alessandro di Michele, Luisa Pascucci, Francesca deFranco, Teresa Zelante, Cinzia Antognelli, Gabriele Cruciani, Vincenzo Nicola Talesa, Rita Romani, Francesca Fallarino
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 6, Pp n/a-n/a (2024)
Abstract Dendritic cells (DCs) are essential orchestrators of immune responses and represent potential targets for immunomodulation in autoimmune diseases. Human amniotic fluid secretome is abundant in immunoregulatory factors, with extracellular ves
Externí odkaz:
https://doaj.org/article/80e2a8da2cd0423bbb570923823c1a54
Autor:
Estevão Carlos Silva Barcelos, Chiara Rompietti, Francesco Maria Adamo, Erica Dorillo, Filomena De Falco, Beatrice Del Papa, Stefano Baldoni, Manuel Nogarotto, Angela Esposito, Silvia Capoccia, Clelia Geraci, Daniele Sorcini, Arianna Stella, Roberta Arcaleni, Valentina Tini, Flávia Imbroisi Valle Errera, Emanuela Rosati, Paolo Sportoletti
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionConstitutive activation of NOTCH1-wild-type (NT1-WT) signaling is associated with poor outcomes in chronic lymphocytic leukemia (CLL), and NOTCH1 mutation (c.7541_7542delCT), which potentiates NOTCH1 signaling, worsens the prognosis. Howe
Externí odkaz:
https://doaj.org/article/42a87a28abc246f28270a9eea157bbfb
Autor:
Filomena De Falco, Chiara Rompietti, Daniele Sorcini, Angela Esposito, Annarita Scialdone, Stefano Baldoni, Beatrice Del Papa, Francesco Maria Adamo, Estevão Carlos Silva Barcelos, Erica Dorillo, Arianna Stella, Mauro Di Ianni, Isabella Screpanti, Paolo Sportoletti, Emanuela Rosati
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-12 (2022)
Abstract NOTCH1 alterations have been associated with chronic lymphocytic leukemia (CLL), but the molecular mechanisms underlying NOTCH1 activation in CLL cells are not completely understood. Here, we show that GSK3β downregulates the constitutive l
Externí odkaz:
https://doaj.org/article/7b3c1fed542c47f9a546c4f1d4b17638
Autor:
Mauro Di Ianni, Stefano Baldoni, Beatrice Del Papa, Patrizia Aureli, Erica Dorillo, Filomena De Falco, Elisa Albi, Emanuela Varasano, Ambra Di Tommaso, Raffaella Giancola, Patrizia Accorsi, Gianluca Rotta, Chiara Rompietti, Estevão Carlos Silva Barcelos, Antonio Francesco Campese, Paolo Di Bartolomeo, Isabella Screpanti, Emanuela Rosati, Franca Falzetti, Paolo Sportoletti
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
To investigate chronic lymphocytic leukemia (CLL)-initiating cells, we assessed NOTCH1 mutation/expression in hematopoietic stem cells (HSCs). In NOTCH1-mutated CLL, we detected subclonal mutations in 57% CD34+/CD38− HSCs. NOTCH1 mutation was prese
Externí odkaz:
https://doaj.org/article/22cb5b5b90a04145889dadc04b8f6e35