Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Ester Simeone"'
Autor:
Domenico Mallardo, Rachel Woodford, Alexander M. Menzies, Lisa Zimmer, Andrew williamson, Egle Ramelyte, Florentia Dimitriou, Alexandre Wicky, Roslyn Wallace, Mario Mallardo, Alessio Cortellini, Alfredo Budillon, Victoria Atkinson, Shahneen Sandhu, Michielin Olivier, Reinhard Dummer, Paul Lorigan, Dirk Schadendorf, Georgina V. Long, Ester Simeone, Paolo A. Ascierto
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background The combination of nivolumab + relatlimab is superior to nivolumab alone in the treatment of naive patients and has activity in PD-1 refractory melanoma. We had previously observed a reduced expression of LAG3 in melanoma tissue f
Externí odkaz:
https://doaj.org/article/f9c9d70fb3694e94a830225a5081faab
Autor:
Domenico Mallardo, Mario Fordellone, Andrew White, Margaret Ottaviano, Francesca Sparano, Michael Bailey, Arianna Bianca Facchini, Sufey Ong, Piera Maiolino, Corrado Caracò, Sarah Church, Ernesta Cavalcanti, Sarah Warren, Alfredo Budillon, Alessandra Cesano, Ester Simeone, Paolo Chiodini, Paolo Antonio Ascierto
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Identifying response markers is highly needed to guide the treatment strategy in patients with metastatic melanoma. Methods A retrospective study was carried out in patients with unresectable/metastatic melanoma (stage IIIb–IV),
Externí odkaz:
https://doaj.org/article/6a0f6b12d40a45cdad984752d02e73b2
Autor:
Domenico Galati, Serena Zanotta, Mariaelena Capone, Gabriele Madonna, Domenico Mallardo, Marilena Romanelli, Ester Simeone, Lucia Festino, Francesca Sparano, Rosa Azzaro, Rosaria De Filippi, Antonio Pinto, Chrystal M. Paulos, Paolo A. Ascierto
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Nivolumab is an anti-PD1 antibody that has dramatically improved metastatic melanoma patients’ outcomes. Nevertheless, many patients are resistant to PD-1 inhibition, occasionally experiencing severe off-target immune toxicity.
Externí odkaz:
https://doaj.org/article/fc778616ad9c4244b22051d8743c7e29
Autor:
Francesca Sparano, Corrado Caracò, Ester Simeone, Assunta Esposito, Lucia Festino, Alfredo Budillon, Domenico Mallardo, Vito Vanella, Paolo Ascierto, Claudia Trojaniello, Maria Grazia Vitale, Margaret Ottaviano, Mario Mallardo, Eleonora Cioli, Teresa De Cristofaro, Boanca Arianna Facchini, Paolo Meinardi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/75f15d67d13e430bb8ef5d12d7e09c64
Autor:
Francesca Sparano, Corrado Caracò, Ester Simeone, Lucia Festino, Alfredo Budillon, Domenico Mallardo, Vito Vanella, Ernesta Cavalcanti, Paolo Ascierto, Claudia Trojaniello, Maria Grazia Vitale, Grazia D’Angelo, Marilena Tuffanelli, Sergio Arpino, Anita Minopoli, Mario Mallardo, Eleonora Cioli, Benedetta Alfano
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/9930f747cc5a44578a8c1d38f910d4e1
Autor:
Michael Bailey, Andrew White, Francesca Sparano, Alessandra Cesano, Corrado Caracò, Ester Simeone, Alfredo Budillon, Sarah Warren, SuFey Ong, Domenico Mallardo, Sarah Church, Ernesta Cavalcanti, Paolo Ascierto, Margaret Ottaviano, Paolo Chiodini, Piera Maiolino, Mario Fordellone, Bianca Arianna Facchini
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/27910087b747468b892288cebab2428c
Autor:
Michael Bailey, Andrew White, Francesca Sparano, Alessandra Cesano, Corrado Caracò, Ester Simeone, Lucia Festino, Alfredo Budillon, Sarah Warren, Domenico Mallardo, Sarah Church, Vito Vanella, Ernesta Cavalcanti, Paolo Ascierto, Claudia Trojaniello, Maria Grazia Vitale, Margaret Ottaviano, Paolo Chiodini, Marilena Tuffanelli, Mario Fordellone, Bianca Arianna Facchini
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/88c28a6e9f0a4bd8bd85c25a054338ec
Autor:
Domenico Mallardo, Ester Simeone, Lucia Festino, Marilena Tuffanelli, Vito Vanella, Claudia Trojaniello, Maria Grazia Vitale, Margaret Ottaviano, Mariaelena Capone, Gabriele Madonna, Francesca Sparano, Eleonora Cioli, Luigi Scarpato, Marco Palla, Rossella Di Trolio, Paolo Meinardi, Corrado Caracò, Gerardo Ferrara, Paolo Muto, Ernesta Cavalcanti, Paolo Antonio Ascierto
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-6 (2023)
Abstract Background Prognostic factors for initial response of advanced cutaneous squamous cell carcinoma to cemiplimab treatment are lacking. Il-6 has been found to affect immune cell populations which impact tumor development. The aim was to invest
Externí odkaz:
https://doaj.org/article/9ccd3117e02744a0b6acca57fd56a3c0
Autor:
Domenico Mallardo, Ester Simeone, Vito Vanella, Maria Grazia Vitale, Marco Palla, Luigi Scarpato, Miriam Paone, Teresa De Cristofaro, Valentina Borzillo, Alessio Cortellini, Francesca Sparano, Sandro Pignata, Francesco Fiore, Corrado Caracò, Piera Maiolino, Antonella Petrillo, Ernesta Cavalcanti, Secondo Lastoria, Paolo Muto, Alfredo Budillon, Sarah Warren, Paolo Antonio Ascierto
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background The clinical observation showed a potential additive effect of anti-PD-1 agents and cetirizine in patients with advanced melanoma. Methods Clinical outcomes of concomitant cetirizine/anti-PD-1 treatment of patients with stage IIIb
Externí odkaz:
https://doaj.org/article/a1de88eacd334c7ebe21732707f03220
Autor:
Ester Simeone, Giosuè Scognamiglio, Mariaelena Capone, Diana Giannarelli, Antonio M. Grimaldi, Domenico Mallardo, Gabriele Madonna, Marcello Curvietto, Assunta Esposito, Fabio Sandomenico, Francesco Sabbatino, Nicholas L. Bayless, Sarah Warren, SuFey Ong, Gerardo Botti, Keith T. Flaherty, Soldano Ferrone, Paolo A. Ascierto
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-10 (2021)
Abstract Background Studies carried out in vitro and in a mouse model have shown that BRAF inhibitors enhance the effects of IFN-α on BRAFV600E melanoma cells through the inhibition of ERK. Therefore, the combination of vemurafenib and IFN-α in pat
Externí odkaz:
https://doaj.org/article/86e55258d57a4fdc9a2470824a69f5e9