CDK11 Promotes Cytokine-Induced Apoptosis in Pancreatic Beta Cells Independently of Glucose Concentration and Is Regulated by Inflammation in the NOD Mouse Model

Autor: Ester Sala, Celia Vived, Júlia Luna, Noemí Alejandra Saavedra-Ávila, Upasana Sengupta, A. Raúl Castaño, Sabrina Villar-Pazos, Laura Haba, Joan Verdaguer, Ana B. Ropero, Thomas Stratmann, Javier Pizarro, Manuel Vázquez-Carrera, Angel Nadal, Jill M. Lahti, Conchi Mora

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

BackgroundPancreatic islets are exposed to strong pro-apoptotic stimuli: inflammation and hyperglycemia, during the progression of the autoimmune diabetes (T1D). We found that the Cdk11(Cyclin Dependent Kinase 11) is downregulated by inflammation in

Externí odkaz: https://doaj.org/article/43d700c8d29a47dc8cba0c3b8b15aa2f

Análisis de conglomerados de cáncer. El caso del barrio de Campdorà, Girona.

Autor: Aitana Lertxundi-Manterola, Marc Saez, Rafael Marcos-Gragera, Àngel Izquierdo, Nuri Pibernat, Ester Sala, Neus Camps

Publikováno v: Revista Española de Salud Pública, Vol 79, Iss 4, Pp 443-452 (2005)

Un conglomerado de casos puede definirse como la aparición de un número de casos de una enfermedad en una cantidad superior a la que se esperaría para un determinado grupo de población, un área geográfica y un período de tiempo determinado. En

Externí odkaz: https://doaj.org/article/12ff8e3aacd5442cb99ee8c56f367508

The Power of Wild Plants in Feeding Humanity: A Meta-Analytic Ethnobotanical Approach in the Catalan Linguistic Area

Autor: Teresa Garnatje, Marc Talavera, Joan Vallès, Montse Parada, Airy Gras, Jon Marín, Ester Sala

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Foods, Vol 10, Iss 61, p 61 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Foods
Volume 10
Issue 1
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)

Wild food plants (WFP) have always been present in our kitchen, although they have not always been given the same importance as crops. In the Catalan linguistic area (CLA), covered in this paper, WFP were of great importance as a subsistence food not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd7864b291ef7a4906de05afda4858f
http://hdl.handle.net/2445/173827

Molecular Targets of inflammation in pancreatic endocrine cells in Type 1 Diabetes (T1D)

Autor: Conchi Mora, Ester Sala, Noemí Alejandra Saavedra-Ávila, Upasana Sengupta, Celia Vived, Joan Verdaguer, Thomas Stratmann, Jill Lahti

Publikováno v: The Journal of Immunology. 202:180.20-180.20

T1D (Type 1 Diabetes) is an autoimmune disorder caused by the immune-mediated destruction of insulin-producing beta cells in the pancreas. There are direct mechanisms that have been demonstrated to cause final beta cell demise, such as the pathways t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8386c0a96508180695c54475ff47669e
https://doi.org/10.4049/jimmunol.202.supp.180.20

Inflammation targets cell-cycle actors at the onset of autoimmune diabetes (T1D) in pancreatic endocrine cells from the NOD mouse model

Autor: Conchi Mora, Noemí Alejandra Saavedra-Ávila, Ester Sala, Upasana Sengupta, Joan Verdaguer, Thomas Stratmann, Peter Sicinski, Jill Lahti

Publikováno v: The Journal of Immunology. 200:100.7-100.7

Prior to the massive beta cell demise that leads to autoimmune diabetes (Type 1 Diabetes or T1D), profound profiling changes are imprinted onto the beta cell by an aggressive pro-inflammatory environment that interferes negatively with cell functiona

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e14dedb42ffaed433383a532667330fb
https://doi.org/10.4049/jimmunol.200.supp.100.7