Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ester Rabizadeh"'
Autor:
Orit Uziel, Ofir Wolach, Jardena Nordenberg, Meir Lahav, Ester Rabizadeh, Yonatan Edel, Anna Gutkin, Einat Beery, Hadar Goldvaser
Publikováno v:
British Journal of Cancer
Background: Telomerase (human telomerase reverse transcriptase (hTERT)) is considered a hallmark of cancer. The aim of our study was to evaluate the feasibility of the detection of hTERT transcripts in serum as a ‘pan-cancer’ diagnostic method. M
Publikováno v:
Leukemia Research. 28:243-248
B-chronic lymphocytic leukemia (B-CLL) cells have a long survival owing to an alteration in the normal pathways of apoptosis. CLL cells have been found to produce and secrete vascular endothelial growth factor (VEGF). In addition to its major role in
Publikováno v:
British Journal of Haematology. 113:400-406
A large proportion of B-chronic lymphocytic leukaemia (B-CLL) cells express the anti-apoptotic protein Bcl-2. Basic fibroblast growth factor (bFGF) has been shown to upregulate the expression of Bcl-2 in B-CLL cell lines. Vascular endothelial growth
Publikováno v:
Medical Oncology. 17:314-318
Preliminary reports involving a number of different kinds of tumors have indicated that microvessel quantification may be useful in predicting disease outcome. The aim of this study was to examine the relationship between microvessel density (MVD) as
Autor:
Yael Zimrah, Ester Rabizadeh, Matityahu Shaklai, Ada Rephaeli, Margaretta Ruse, Abraham Nudelman, Adina Aviram
Publikováno v:
Journal of Medicinal Chemistry. 35:687-694
The antitumor activity of novel prodrugs butyric acid was examined. The in vitro effect of the compounds on induction of cytodifferentiation and on inhibition of proliferation and clonogenicity showed that (pivaloyloxy)methyl butyrate (1a) (labeled A
Publikováno v:
Journal of Cellular Physiology. 143:154-159
Proliferation-associated changes in calcium metabolism were investigated employing the promyelocytic HL-60 and monoblastic U-937 cell lines. The cells were stimulated to proliferate employing mitogenic factors as follows. 1) Transferrin or insulin: H
Autor:
Ester Rabizadeh, Mati Shaklai, Yael Zimra, Abraham Nudelman, Adina Aviram, Ada Rephaeli, Regina Zhuk
Publikováno v:
Journal of cancer research and clinical oncology. 126(12)
Pivaloyloxymethyl butyrate (AN-9), a butyric acid (BA) prodrug, exhibited low toxicity and significant anticancer activity in vitro and in vivo. The purpose of this study was to elucidate the basis for AN-9 increased anticancer activity compared to B
Autor:
A Novogrodsky, Ester Rabizadeh, Mati Shaklai, Abraham Nudelman, Jardena Nordenberg, Adina Aviram, Ada Rephaeli, Yael Zimra
Publikováno v:
International Journal of Oncology.
A study of the effects of three differentiating agents, butyric acid, retinoic acid and cytosine arabinoside on proliferation and differentiation of primary cultures, obtained from sixteen patients with myelo-proliferative disorder was conducted. The
Publikováno v:
FEBS Letters. (3):225-229
The novel prodrug of butyric acid (BA), pivaloyloxymethyl butyrate, has been shown, in vitro, to induce differentiation and inhibit leukemic cell proliferation. The prodrug affects the cells in vitro at lower concentration and at least 100 times fast