Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ester Kalef-Ezra"'
Autor:
Ester Kalef-Ezra, Zeliha Gozde Turan, Diego Perez-Rodriguez, Ida Bomann, Sairam Behera, Caoimhe Morley, Sonja W. Scholz, Zane Jaunmuktane, Jonas Demeulemeester, Fritz J. Sedlazeck, Christos Proukakis
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract The presence of somatic mutations, including copy number variants (CNVs), in the brain is well recognized. Comprehensive study requires single-cell whole genome amplification, with several methods available, prior to sequencing. Here we comp
Externí odkaz:
https://doaj.org/article/33142598378f4a9a88091ba6a21379f4
Autor:
Ester Kalef-Ezra, Fred Jonathan Edzeamey, Adamo Valle, Hassan Khonsari, Paula Kleine, Carlo Oggianu, Sahar Al-Mahdawi, Mark A. Pook, Sara Anjomani Virmouni
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionFriedreich’s ataxia (FRDA) is an inherited recessive neurodegenerative disorder caused by a homozygous guanine-adenine-adenine (GAA) repeat expansion within intron 1 of the FXN gene, which encodes the essential mitochondrial protein fra
Externí odkaz:
https://doaj.org/article/536964334c104f74840ef5dd71a79726
Autor:
Mursal Sherzai, Adamo Valle, Nicholas Perry, Ester Kalef-Ezra, Sahar Al-Mahdawi, Mark Pook, Sara Anjomani Virmouni
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Friedreich’s ataxia (FRDA) is a progressive neurodegenerative disorder caused by a homozygous GAA repeat expansion mutation in intron 1 of the frataxin gene (FXN), which instigates reduced transcription. As a consequence, reduced levels of frataxin
Externí odkaz:
https://doaj.org/article/1468f661eccb4df3ac3bbd6f101a879e
Publikováno v:
Biology, Vol 6, Iss 1, p 11 (2017)
Glutamate dehydrogenase (GDH) is a hexameric enzyme that catalyzes the reversible conversion of glutamate to α-ketoglutarate and ammonia while reducing NAD(P)+ to NAD(P)H. It is found in all living organisms serving both catabolic and anabolic react
Externí odkaz:
https://doaj.org/article/701a0dc953c948709fc5e5c7351d7df6
Autor:
Nitsa Katrakili, Kostas Tokatlidis, Ester Kalef-Ezra, Ioannis Zaganas, Andreas Plaitakis, Dimitra Kotzamani
Publikováno v:
Biochemical Journal
Mammalian glutamate dehydrogenase (GDH), a nuclear-encoded enzyme central to cellular metabolism, is among the most abundant mitochondrial proteins (constituting up to 10% of matrix proteins). To attain such high levels, GDH depends on very efficient
Publikováno v:
Biology
Biology, Vol 6, Iss 1, p 11 (2017)
Biology, Vol 6, Iss 1, p 11 (2017)
Glutamate dehydrogenase (GDH) is a hexameric enzyme that catalyzes the reversible conversion of glutamate to α-ketoglutarate and ammonia while reducing NAD(P)+ to NAD(P)H. It is found in all living organisms serving both catabolic and anabolic react
Publikováno v:
Neurochemical research. 39(3)
Mitochondria biogenesis is a fundamental process for the organization and normal function of all cells. Since the majority of mitochondrial proteins are synthesized in the cytosol, protein import is the major mechanism for mitochondria biogenesis. We