Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Ester Dunnebach"'
1
Akademický článek
Clinical Grade Production of Wilms’ Tumor-1 Loaded Cord Blood-Derived Dendritic Cells to Prevent Relapse in Pediatric AML After Cord Blood Transplantation
Autor: Maud Plantinga, Vania Lo Presti, Colin G. de Haar, Ester Dünnebach, Alejandro Madrigal, Caroline A. Lindemans, Jaap Jan Boelens, Stefan Nierkens
Publikováno v: Frontiers in Immunology, Vol 11 (2020)
Hematopoietic cell transplantation (HCT) is a last resort, potentially curative treatment option for pediatric patients with refractory acute myeloid leukemia (AML). Cord blood transplantation (CBT) results in less relapses and less graft-versus-host
Externí odkaz: https://doaj.org/article/ae61d80aa4024b78b602ce6cc78c2473
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3
Akademický článek
Combining CRISPR-Cas9 and TCR exchange to generate a safe and efficient cord blood-derived T cell product for pediatric relapsed AML
Autor: Zsolt Sebestyen, Jürgen Kuball, Maud Plantinga, Anja Krippner-Heidenreich, S Nierkens, Ester Dunnebach, Vania Lo Presti, Olaf T Heidenreich, Angelo Meringa, Alice van Velzen, Aida Valera Moreira, Ronald W Stam, Rishi S Kotecha, Annelisa Cornel, Niek P van Til
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Hematopoietic cell transplantation (HCT) is an effective treatment for pediatric patients with high-risk, refractory, or relapsed acute myeloid leukemia (AML). However, a large proportion of transplanted patients eventually die due to rela
Externí odkaz: https://doaj.org/article/201ace7f9fc54b5eb4254af5c2cc872c
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4
Akademický článek
Targeting pediatric cancers via T-cell recognition of the monomorphic MHC class I-related protein MR1
Autor: Aimee du Chatinier, Zsolt Sebestyen, Jürgen Kuball, Stefan Nierkens, Anja Krippner-Heidenreich, Yuyan Lu, Ana P Lopes, Ester Dunnebach, Denise A M H van den Beemt, Sebastiaan van Heesch, Annelisa M. Cornel, Loutje van der Sman, Jip T van Dinter, Marta Arrabito, Marliek van Hoesel, Thomas A Kluiver, Noël M M Dautzenberg, Linde Dekker, Jorik M van Rijn, Juliane L Buhl, Farnaz Barneh, Luca Lo Nigro, Esther Hulleman, Jarno Drost, Olaf T Heidenreich, Weng Chuan Peng
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 3 (2024)
Human leukocyte antigen (HLA) restriction of conventional T-cell targeting introduces complexity in generating T-cell therapy strategies for patients with cancer with diverse HLA-backgrounds. A subpopulation of atypical, major histocompatibility comp
Externí odkaz: https://doaj.org/article/74ecceb9112048d6b772df7929f01087
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5
Akademický článek
Epigenetic modulation of neuroblastoma enhances T cell and NK cell immunogenicity by inducing a tumor-cell lineage switch
Autor: Judith Wienke, S Nierkens, Miranda P Dierselhuis, Jan J Molenaar, Annelisa M Cornel, Ester Dunnebach, Damon A Hofman, Sanjukta Das, Satyaki Sengupta, Femke van den Ham, Josephine G M Strijker, Denise A M H van den Beemt, Anke H W Essing, Bianca Koopmans, Sem A G Engels, Vania Lo Presti, Celina S Szanto, Rani E George, Sebastiaan van Heesch
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
Background Immunotherapy in high-risk neuroblastoma (HR-NBL) does not live up to its full potential due to inadequate (adaptive) immune engagement caused by the extensive immunomodulatory capacity of HR-NBL. We aimed to tackle one of the most notable
Externí odkaz: https://doaj.org/article/7142ba69053342a98bcc3622acf2b968
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6
Epigenetic modulation of neuroblastoma enhances T cell and NK cell immunogenicity by inducing a tumor-cell lineage switch
Autor: Annelisa M Cornel, Ester Dunnebach, Damon A Hofman, Sanjukta Das, Satyaki Sengupta, Femke van den Ham, Judith Wienke, Josephine G M Strijker, Denise A M H van den Beemt, Anke H W Essing, Bianca Koopmans, Sem A G Engels, Vania Lo Presti, Celina S Szanto, Rani E George, Jan J Molenaar, Sebastiaan van Heesch, Miranda P Dierselhuis, S Nierkens
Publikováno v: Journal for ImmunoTherapy of Cancer. 10:e005002
BackgroundImmunotherapy in high-risk neuroblastoma (HR-NBL) does not live up to its full potential due to inadequate (adaptive) immune engagement caused by the extensive immunomodulatory capacity of HR-NBL. We aimed to tackle one of the most notable
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523204a6719fb30ea68604533c303a61
https://doi.org/10.1136/jitc-2022-005002
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7
P09.02 Epigenetic modulation of neuroblastoma enhances T- and NK cell immunogenicity via induction of surface expression of MHC class I and MICA/MICB
Autor: Damh van den Beemt, Ester Dunnebach, Annelisa M. Cornel, MP van Dierselhuis, Stefan Nierkens
Publikováno v: Poster Presentations.
Background Neuroblastoma (NBL) is the most common pediatric solid tumor and responsible for about 15% of all pediatric cancer deaths. The majority of high-risk (HR) patients suffers from relapse after intense therapy regimens, resulting in a 5-year s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::becdf76b862009869040f080a2a54867
https://doi.org/10.1136/jitc-2021-itoc8.52
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8
Efficient lentiviral transduction method to gene modify cord blood CD8(+) T cells for cancer therapy applications
Autor: Ester Dunnebach, Jaap Jan Boelens, Niek P. van Til, Stefan Nierkens, Vania Lo Presti, Jürgen Kuball, Annelisa M. Cornel, Maud Plantinga
Publikováno v: Molecular Therapy-Methods and Clinical Development, 21, 357-368. Cell Press
Molecular Therapy. Methods & Clinical Development
Lo Presti, V, Cornel, A M, Plantinga, M, Dunnebach, E, Kuball, J, Boelens, J J, Nierkens, S & van Til, N P 2021, ' Efficient lentiviral transduction method to gene modify cord blood CD8(+) T cells for cancer therapy applications ', Molecular Therapy-Methods and Clinical Development, vol. 21, pp. 357-368 . https://doi.org/10.1016/j.omtm.2021.03.015
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss, Pp 357-368 (2021)
Adoptive T cell therapy utilizing tumor-specific autologous T cells has shown promising results for cancer treatment. However, the limited numbers of autologous tumor-associated antigen (TAA)-specific T cells and the functional aberrancies, due to di
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c61d04c20547aa9016ecc2e309918b
https://research.vumc.nl/en/publications/af1b932e-b309-4e9f-a4ec-1807cf806d6c
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9
Immune Monitoring during Therapy Reveals Activitory and Regulatory Immune Responses in High-Risk Neuroblastoma
Autor: Ester Dunnebach, Celina L. Szanto, Miranda P Dierselhuis, Eveline M. Delemarre, Alwin D. R. Huitema, Coco de Koning, Stefan Nierkens, Jaap-Jan Boelens, Lieve G. A. M. Tytgat, Max M. van Noesel, Annelisa M. Cornel, Kathelijne C. J. M. Kraal, Michelle L. Tas, Sara M. Tamminga, Denise A. M. H. van den Beemt
Publikováno v: Cancers
Volume 13
Issue 9
Cancers, Vol 13, Iss 2096, p 2096 (2021)
Simple Summary Neuroblastoma is a type of childhood cancer accounting for approximately 15% of childhood cancer deaths. Despite intensive treatment, including immunotherapy, prognosis of high-risk neuroblastoma is poor. Increasing amounts of research
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e365b288eead6520804b62288370f8b0
http://europepmc.org/articles/PMC8123570
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10
CD14 Expressing Precursors Give Rise to Highly Functional Conventional Dendritic Cells for Use as Dendritic Cell Vaccine
Autor: Ester Dunnebach, Stefan Nierkens, Maud Plantinga, Denise A. M. H. van den Beemt
Publikováno v: Cancers, Vol 13, Iss 3818, p 3818 (2021)
Cancers
Volume 13
Issue 15
Simple Summary Dendritic cells are attractive candidates for immunotherapy to prevent disease recurrence in cancer patients. Dendritic cells are a plastic population of antigen presenting cells and a variety of protocols have been described to genera
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48cf671a9486cabc5df0dd3438c4d151
https://doi.org/10.3390/cancers13153818
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