Short- and medium-term impact of bariatric surgery on the activities of CYP2D6, CYP3A4, CYP2C9, and CYP1A2 in morbid obesity

Autor: Magí Farré, Olga Castañer, Clara Pérez-Mañá, Jose Rodríguez-Morató, Mitona Pujadas, Esther Papaseit, David Benaiges, Rafael de la Torre, Ester Civit, Albert Goday, Klaus Langohr, José M. Ramón

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Scientific Reports
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)

Morbid obesity and bariatric surgery induce anatomical, physiological and metabolic alterations that may alter the body's disposition of drugs. Current literature on this topic is limited and sometimes inconsistent. Cytochrome P450 (CYP) is a superfa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3855d0a54f8091f863c842de4f24de68
http://hdl.handle.net/2072/445909

COMT val158met and 5-HTTLPR Genetic Polymorphisms Moderate Executive Control in Cannabis Users

Autor: Joan Rodríguez, Rafael de la Torre, Ester Civit, Antonio Verdejo-García, Aida Cuenca, Susana De Sola Llopis, Magí Farré, J. Peña-Casanova, Elisabet Cuyàs, Klaus Langohr, Ana B. Fagundo

Publikováno v: Neuropsychopharmacology. 38:1598-1606

The adverse effects of cannabis use on executive functions are still controversial, fostering the need for novel biomarkers able to unveil individual differences in the cognitive impact of cannabis consumption. Two common genetic polymorphisms have b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988d0716fa80f9223b878c5f21f6234d
https://doi.org/10.1038/npp.2013.59

Gas chromatography–mass spectrometry assay for the simultaneous quantification of drugs of abuse in human placenta at 12th week of gestation

Autor: Simona Pichini, María Falcón, Xavier Joya, Aurelio Luna, Rafael de la Torre, Oriol Vall, Ester Civit, Oscar Garcia-Algar, Mitona Pujadas

Publikováno v: Forensic Science International. 196:38-42

We describe the development and validation of a method for the quantification of drugs of abuse, using gas chromatography-mass spectrometry (GC/MS), in human placenta. Concentration ranges covered were 5-500 ng/g for amphetamine, methamphetamine, MDM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc9161a10a92c278fc10541f7c87eca
https://doi.org/10.1016/j.forsciint.2009.12.044

Decision-making impairment predicts 3-month hair-indexed cocaine relapse

Autor: José Miguel Martínez-González, Antonio Verdejo-García, Ester Civit, Óscar M. Lozano, Natalia Albein-Urios, Rafael de la Torre

Publikováno v: Psychopharmacology. 231(21)

One of the key outstanding challenges in cocaine dependence research is determining who is at risk of relapsing during treatment. We examined whether cognitive decision-making profiles predict objectively (hair) indexed cocaine relapse at 3-month fol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872c71264edee3907cc84271f9eba7d4
https://pubmed.ncbi.nlm.nih.gov/24728653

High throughput analysis of drugs of abuse in hair by combining purposely designed sample extraction compatible with immunometric methods used for drug testing in urine

Autor: M. Miozzo, Ester Civit, Fiorenza Svaizer, R. de la Torre, Andrea Lotti, Massimo Gottardi

Publikováno v: Forensic science international. 196(1-3)

Drug testing in hair usually requires a rather complex sample treatment before drugs are amenable to analysis by either immunological and/or chromatographic coupled to mass spectrometry methods. Immunological methods applied are usually dedicated to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3f58d20bad4625173a214e0aa91237d
https://pubmed.ncbi.nlm.nih.gov/20080367