Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ester Bonfill-Teixidor"'
Autor:
Carlota Rubio-Perez, Ester Planas-Rigol, Juan L. Trincado, Ester Bonfill-Teixidor, Alexandra Arias, Domenica Marchese, Catia Moutinho, Garazi Serna, Leire Pedrosa, Raffaella Iurlaro, Francisco Martínez-Ricarte, Laura Escudero, Esteban Cordero, Marta Cicuendez, Sara Ruiz, Genís Parra, Paolo Nuciforo, Josep Gonzalez, Estela Pineda, Juan Sahuquillo, Josep Tabernero, Holger Heyn, Joan Seoane
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The use of CSF for diagnosis of metastatic brain tumors could be of clinical and patient benefit. Here the authors undertake a single-cell RNA analysis of CSF and brain to determine whether the phenotype in the CSF is reflective of the phenotype in t
Externí odkaz:
https://doaj.org/article/50b186a5ef3f4b8e915baf48cb69dbc4
Autor:
Mónica Pascual-García, Ester Bonfill-Teixidor, Ester Planas-Rigol, Carlota Rubio-Perez, Raffaella Iurlaro, Alexandra Arias, Isabel Cuartas, Ada Sala-Hojman, Laura Escudero, Francisco Martínez-Ricarte, Isabel Huber-Ruano, Paolo Nuciforo, Leire Pedrosa, Carolina Marques, Irene Braña, Elena Garralda, María Vieito, Massimo Squatrito, Estela Pineda, Francesc Graus, Carmen Espejo, Juan Sahuquillo, Josep Tabernero, Joan Seoane
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
LIF is a pleiotropic cytokine that promotes an immunosuppressive microenvironment and has critical functions in embryonic development. Here, the authors show that LIF regulates CD8+ T cell tumor infiltration in cancer by repressing CXCL19 and promoti
Externí odkaz:
https://doaj.org/article/eafd754e38d148f4af2177cb43fd4fa5
Autor:
Mattia Gallizioli, Francesc Miró-Mur, Amaia Otxoa-de-Amezaga, Roger Cugota, Angélica Salas-Perdomo, Carles Justicia, Vanessa H. Brait, Francisca Ruiz-Jaén, Maria Arbaizar-Rovirosa, Jordi Pedragosa, Ester Bonfill-Teixidor, Mathias Gelderblom, Tim Magnus, Eva Cano, Carlos del Fresno, David Sancho, Anna M. Planas
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108291- (2020)
Summary: Brain CD11c+ cells share features with microglia and dendritic cells (DCs). Sterile inflammation increases brain CD11c+ cells, but their phenotype, origin, and functions remain largely unknown. We report that, after cerebral ischemia, microg
Externí odkaz:
https://doaj.org/article/66c02ae0ed0f40bfa4046e52536e1616
Autor:
Irene Pecharroman, Laura Sole, Daniel Alvarez Villanueva, Joan Bertran, Yolanda Guillén, Teresa Lobo, Josune Alonso-Marañon, Maria Martínez, Violeta García-Hernández, Gemma Gimenez, Carlota Colomer, María Carmen Mulero, Jessica Gonzales, Ramon Salazar, Cristina Santos, Marta Garrido, Alberto Villanueva, Eva Borràs, Eduard Sabidó, Ester Bonfill-Teixidor, Raffaella Iurlaro, Angela Montoto, Joan Seoane, Mar Iglesias, Anna Bigas, Lluis Espinosa
Activation of the IKK kinase complex has recurrently been linked to colorectal cancer (CRC) initiation and progression. However, identification of downstream effectors other than NF-kB has remained elusive. Analysis of IKK-dependent substrates after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bc181ba48fb489751d04fa6c9f35260
https://doi.org/10.21203/rs.3.rs-1922801/v2
https://doi.org/10.21203/rs.3.rs-1922801/v2
Autor:
Joan Seoane, Pablo Umaña, Josep Tabernero, Maria Vieito, Joan Carles, Paolo Nuciforo, Josep González, Alberto Di Somma, Luis Reyes-Figueroa, Estela Pineda, Christian Klein, Marina Bacac, Sara Colombetti, Johannes Sam, Franz Osl, Joerg Mueller, Stefanie Briner, Marine Richard, Virginie Steinhart, Thomas Pöschinger, Linda Fahrni, Xavier Guardia-Reyes, Simona Casalino, Marta Cicuendez, Esteban Cordero, Francisco Martínez-Ricarte, Alba Martínez-Moreno, Isabel Cuartas, Anne Freimoser-Grundschober, Valeria Nicolini, Alexandra Arias, Ester Bonfill-Teixidor, Ester Planas-Rigol, Inja Waldhauer, Raffaella Iurlaro
Supplementary Figure from A Novel EGFRvIII T-Cell Bispecific Antibody for the Treatment of Glioblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657bca3e4a42077f3949a8e50f002546
https://doi.org/10.1158/1535-7163.22523662.v1
https://doi.org/10.1158/1535-7163.22523662.v1
Autor:
Joan Seoane, Patricia Giblin, Jean-Philippe Julien, Judit Anido, Isabel Huber-Ruano, Johan Fransson, Dorothea Maetzel, Melissa Beilschmidt, Alexandre Bosch, Esther Lau, AJ Robert McGray, Almudena Neva-Alejo, Olga Egorova, Peter Bayliss, Swetha Raman, Alexandra Arias, Raffaella Iurlaro, Ester Bonfill-Teixidor, Robin M. Hallett
Supplementary Table 1: Description of TCGA derived mRNA expression cohorts used to examine LIF expression and associated transcript signaturesSupplementary Table 2: Transcription signatures used to identify biological processes and cell types correla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e876e51551f962bd9d5d74e20b1d20a
https://doi.org/10.1158/1078-0432.22482800
https://doi.org/10.1158/1078-0432.22482800
Autor:
Joan Seoane, Piergiorgio Pettazzoni, James R. Bischoff, Josep Tabernero, Eva Muñoz-Couselo, Francisco Martínez-Ricarte, Josep González, Abel Ferres-Pijoan, Thomaz E. Topczewski, Esteban Cordero, Marta Cicuendez, Gabriel Schnetzler, Martin Kornacker, Romi Feddersen, Jan Eckmann, Fabian Köchl, Christina Godfried Sie, Marco Berrera, Thomas Lorber, Luca Mangano, Andrea Romagnani, Jasmin Emmenegger, Isabel Cuartas, Alexandra Arias, Jürgen Wichmann, Cornelia Handl, Raffaella Iurlaro, Ester Bonfill-Teixidor
Supplementary Data from Activity and Resistance of a Brain-Permeable Paradox Breaker BRAF Inhibitor in Melanoma Brain Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212aa6ba78627243358b6b35b8752050
https://doi.org/10.1158/0008-5472.22431899.v1
https://doi.org/10.1158/0008-5472.22431899.v1
Autor:
Joan Seoane, Patricia Giblin, Jean-Philippe Julien, Judit Anido, Isabel Huber-Ruano, Johan Fransson, Dorothea Maetzel, Melissa Beilschmidt, Alexandre Bosch, Esther Lau, AJ Robert McGray, Almudena Neva-Alejo, Olga Egorova, Peter Bayliss, Swetha Raman, Alexandra Arias, Raffaella Iurlaro, Ester Bonfill-Teixidor, Robin M. Hallett
Supplementary Figure 1. Transcriptomic analysis demonstrates an enrichment of immunological pathways in high LIF tumors. Supplementary Figure 2. LIF transcripts are associated with a panel of immunosuppressive macrophage/myeloid signatures across hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b4731b9846b1639fb87315ef90e1b6
https://doi.org/10.1158/1078-0432.22482803
https://doi.org/10.1158/1078-0432.22482803
Autor:
Joan Seoane, Patricia Giblin, Jean-Philippe Julien, Judit Anido, Isabel Huber-Ruano, Johan Fransson, Dorothea Maetzel, Melissa Beilschmidt, Alexandre Bosch, Esther Lau, AJ Robert McGray, Almudena Neva-Alejo, Olga Egorova, Peter Bayliss, Swetha Raman, Alexandra Arias, Raffaella Iurlaro, Ester Bonfill-Teixidor, Robin M. Hallett
Purpose:Leukemia inhibitory factor (LIF) is a multifunctional cytokine with numerous reported roles in cancer and is thought to drive tumor development and progression. Characterization of LIF and clinical-stage LIF inhibitors would increase our unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b3ecc064e7d4473e93036075979191
https://doi.org/10.1158/1078-0432.c.6530999.v1
https://doi.org/10.1158/1078-0432.c.6530999.v1
Autor:
Joan Seoane, Piergiorgio Pettazzoni, James R. Bischoff, Josep Tabernero, Eva Muñoz-Couselo, Francisco Martínez-Ricarte, Josep González, Abel Ferres-Pijoan, Thomaz E. Topczewski, Esteban Cordero, Marta Cicuendez, Gabriel Schnetzler, Martin Kornacker, Romi Feddersen, Jan Eckmann, Fabian Köchl, Christina Godfried Sie, Marco Berrera, Thomas Lorber, Luca Mangano, Andrea Romagnani, Jasmin Emmenegger, Isabel Cuartas, Alexandra Arias, Jürgen Wichmann, Cornelia Handl, Raffaella Iurlaro, Ester Bonfill-Teixidor
The therapeutic benefit of approved BRAF and MEK inhibitors (BRAFi/MEKi) in patients with brain metastatic BRAF V600E/K–mutated melanoma is limited and transient. Resistance largely occurs through the restoration of MAPK signaling via paradoxical B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b43d2542896eb9c701061b84e09659a
https://doi.org/10.1158/0008-5472.c.6514028.v1
https://doi.org/10.1158/0008-5472.c.6514028.v1