Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ester B.M. Remmerswaal"'
Autor:
Iris de Weerdt, Tom Hofland, Renate de Boer, Johan A. Dobber, Julie Dubois, Denise van Nieuwenhuize, Mehrdad Mobasher, Fransien de Boer, Mels Hoogendoorn, Gerjo A. Velders, Marjolein van der Klift, Ester B.M. Remmerswaal, Frederike J. Bemelman, Carsten U. Niemann, Sabina Kersting, Mark-David Levin, Eric Eldering, Sanne H. Tonino, Arnon P. Kater
Publikováno v:
Blood Advances, Vol 3, Iss 17, Pp 2642-2652 (2019)
Abstract: Morbidity and mortality due to immunosuppression remain among the foremost clinical challenges in chronic lymphocytic leukemia (CLL). Although immunosuppression is considered to originate within the lymph node (LN) microenvironment, alterat
Externí odkaz:
https://doaj.org/article/9b70facd4d2e4144a9ac742f72e1a6b0
Autor:
Tom Hofland, Iris de Weerdt, Sanne Endstra, Aldo Jongejan, Laura Platenkamp, Ester B.M. Remmerswaal, Perry D. Moerland, Ineke J.M. ten Berge, Mark-David Levin, Arnon P. Kater, Sanne H. Tonino
Publikováno v:
HemaSphere, Vol 4, Iss 2, p e337 (2020)
Abstract. Acquired T cell dysfunction is a hallmark of chronic lymphocytic leukemia (CLL), and is linked to an increased risk of infections, but also reduced immune surveillance and disappointing responses to autologous T cell-based immunotherapy. Th
Externí odkaz:
https://doaj.org/article/ffac109445dc47468b9b6719d21181a3
Autor:
Michiel C. van Aalderen, Maartje van den Biggelaar, Ester B.M. Remmerswaal, Floris P.J. van Alphen, Alexander B. Meijer, Ineke J.M. ten Berge, René A.W. van Lier
Publikováno v:
Cell Reports, Vol 19, Iss 5, Pp 1068-1079 (2017)
Summary: Pathogens trigger T cells to express distinct sets of effector proteins. To better understand the molecular mechanisms that drive functional specification, we used high-resolution mass spectrometry and label-free protein quantification to me
Externí odkaz:
https://doaj.org/article/98eef1ee188d4fcb8f35110efad6283b
Autor:
Carlos van der Putten, Ester B.M. Remmerswaal, Matty L. Terpstra, Nelly D. van der Bom, Jesper Kers, Ineke J.M. ten Berge, Suzanne E. Geerlings, René A.W. van Lier, Frederike J. Bemelman, Michiel C. van Aalderen
Publikováno v:
Cells, Vol 10, Iss 2, p 288 (2021)
Background: At border sites, and in internal organs, tissue resident memory T cells (TRM) contribute to the immune barrier against pathogens like viruses, bacteria, fungi, and cancer. However, information on the presence and function of these cells i
Externí odkaz:
https://doaj.org/article/bd07b9dcfb0540859617e33e9a2a4c91
Autor:
Gin-Wen Chang, Cheng-Chih Hsiao, Yen-Ming Peng, Felipe A. Vieira Braga, Natasja A.M. Kragten, Ester B.M. Remmerswaal, Martijn D.B. van de Garde, Rachel Straussberg, Gabriele M. König, Evi Kostenis, Vera Knäuper, Linde Meyaard, René A.W. van Lier, Klaas P.J.M. van Gisbergen, Hsi-Hsien Lin, Jörg Hamann
Publikováno v:
Cell Reports, Vol 15, Iss 8, Pp 1757-1770 (2016)
Natural killer (NK) cells possess potent cytotoxic mechanisms that need to be tightly controlled. Here, we explored the regulation and function of GPR56/ADGRG1, an adhesion G protein-coupled receptor implicated in developmental processes and expresse
Externí odkaz:
https://doaj.org/article/5fb9b1597dee429ea865037cd9e6f62f
Autor:
Jack L. McMurray, Anouk von Borstel, Taher E. Taher, Eleni Syrimi, Graham S. Taylor, Maria Sharif, Jamie Rossjohn, Ester B.M. Remmerswaal, Frederike J. Bemelman, Felipe A. Vieira Braga, Xi Chen, Sarah A. Teichmann, Fiyaz Mohammed, Andrea A. Berry, Kirsten E. Lyke, Kim C. Williamson, Michael J.T. Stubbington, Martin S. Davey, Carrie R. Willcox, Benjamin E. Willcox
Publikováno v:
Cell reports, 39(8):110858. Cell Press
γδ T cells are generally considered innate-like lymphocytes, however, an “adaptive-like” γδ compartment has now emerged. To understand transcriptional regulation of adaptive γδ T cell immunobiology, we combined single-cell transcriptomics,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f658ffa16d222361832fbddb4327e33
https://doi.org/10.1016/j.celrep.2022.110858
https://doi.org/10.1016/j.celrep.2022.110858
Autor:
Doreen te Raa, Fernanda Pascutti, Juan J Garcia-Vallejo, Emilie Reinen, Ester B.M. Remmerswaal, René A.W. Van Lier, Eric Eldering, Marinus H.J. Van Oers, Sanne H. Tonino, Arnon P. Kater
Publikováno v:
Blood. 122:2862-2862
Introduction T-cell exhaustion is a state of acquired T-cell dysfunction that arises during chronic infections, but also in the presence of cancer. Chronic lymphocytic leukemia (CLL)-derived CD8+ T cells were recently found to exhibit features of exh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a988029def19dde8f4089aac86a3e96
https://doi.org/10.1182/blood.v122.21.2862.2862
https://doi.org/10.1182/blood.v122.21.2862.2862