Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Ester, Pagano"'
Autor:
Hilal Kalkan, Elisabetta Panza, Ester Pagano, Giuseppe Ercolano, Claudia Moriello, Fabiana Piscitelli, Mónika Sztretye, Raffaele Capasso, Vincenzo Di Marzo, Fabio Arturo Iannotti
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-12 (2023)
Abstract Statins are the most prescribed lipid-lowering agents worldwide. Their use is generally safe, although muscular toxicity occurs in about 1 in 10.000 patients. In this study, we explored the role of the endocannabinoid system (ECS) during mus
Externí odkaz:
https://doaj.org/article/e251330b054e4ee89203a21145513310
Autor:
Tiziana Pecchillo Cimmino, Ester Pagano, Mariano Stornaiuolo, Gabriella Esposito, Rosario Ammendola, Fabio Cattaneo
Publikováno v:
Open Biology, Vol 13, Iss 10 (2023)
The human formyl-peptide receptor 2 (FPR2) is activated by an array of ligands. By phospho-proteomic analysis we proved that FPR2 stimulation induces redox-regulated phosphorylation of many proteins involved in cellular metabolic processes. In this s
Externí odkaz:
https://doaj.org/article/7b18e3c4ca0f4f3fa01b364e3c354996
Autor:
Hilal Kalkan, Ester Pagano, Debora Paris, Elisabetta Panza, Mariarosaria Cuozzo, Claudia Moriello, Fabiana Piscitelli, Armita Abolghasemi, Elisabetta Gazzerro, Cristoforo Silvestri, Raffaele Capasso, Andrea Motta, Roberto Russo, Vincenzo Di Marzo, Fabio Arturo Iannotti
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 3, Pp 1-21 (2023)
Abstract Nothing is known about the potential implication of gut microbiota in skeletal muscle disorders. Here, we provide evidence that fecal microbiota composition along with circulating levels of short‐chain fatty acids (SCFAs) and related metab
Externí odkaz:
https://doaj.org/article/9ff0ef103f6c479fa671fae1ae8b537e
Autor:
Tiziana Pecchillo Cimmino, Ester Pagano, Mariano Stornaiuolo, Gabriella Esposito, Rosario Ammendola, Fabio Cattaneo
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1692 (2022)
Glucose and glutamine play a crucial role in the metabolic reprogramming of cancer cells. Proliferating cells metabolize glucose in the aerobic glycolysis for energy supply, and glucose and glutamine represent the primary sources of carbon atoms for
Externí odkaz:
https://doaj.org/article/c91d9f80881d4427a4ecbd237e180599
Autor:
Cristoforo Silvestri, Ester Pagano, Sébastien Lacroix, Tommaso Venneri, Claudia Cristiano, Antonio Calignano, Olga A. Parisi, Angelo A. Izzo, Vincenzo Di Marzo, Francesca Borrelli
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Inflammatory bowel disorders can be associated with alterations in gut microbiota (dysbiosis) and behavioral disturbances. In experimental colitis, administration of fish oil (FO) or cannabinoids, such as cannabidiol (CBD), reduce inflammation. We in
Externí odkaz:
https://doaj.org/article/bb4007682f8542928d44ebeb7610828c
Autor:
Fabio A. Iannotti, Ester Pagano, Ombretta Guardiola, Simone Adinolfi, Valentina Saccone, Silvia Consalvi, Fabiana Piscitelli, Elisabetta Gazzerro, Giuseppe Busetto, Diego Carrella, Raffaele Capasso, Pier Lorenzo Puri, Gabriella Minchiotti, Vincenzo Di Marzo
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The regenerative capacity of muscle stem cells is impaired in Duchenne muscular dystrophy (DMD). Here, the authors show that the endocannabinoid receptor CB1 is activated by PAX7 in muscle stem cells, and that pharmacological inhibition of CB1 promot
Externí odkaz:
https://doaj.org/article/18374656998d4f538355e4174ad2ce20
Autor:
Lorenzo Di Cesare Mannelli, Fortunato Palma Esposito, Enrico Sangiovanni, Ester Pagano, Carmen Mannucci, Beatrice Polini, Carla Ghelardini, Mario Dell’Agli, Angelo Antonio Izzo, Gioacchino Calapai, Donatella de Pascale, Paola Nieri
Publikováno v:
Pharmaceuticals, Vol 14, Iss 12, p 1329 (2021)
Marine pharmacology is an exciting and growing discipline that blends blue biotechnology and natural compound pharmacology together. Several sea-derived compounds that are approved on the pharmaceutical market were discovered in sponges, marine organ
Externí odkaz:
https://doaj.org/article/9fc1584116c045b78441233753e5ed8f
Autor:
Sanower Hossain, Zannat Urbi, Hidayah Karuniawati, Ramisa Binti Mohiuddin, Ahmed Moh Qrimida, Akrm Mohamed Masaud Allzrag, Long Chiau Ming, Ester Pagano, Raffaele Capasso
Publikováno v:
Life, Vol 11, Iss 4, p 348 (2021)
Infectious disease (ID) is one of the top-most serious threats to human health globally, further aggravated by antimicrobial resistance and lack of novel immunization options. Andrographis paniculata (Burm. f.) Wall. ex Nees and its metabolites have
Externí odkaz:
https://doaj.org/article/b66a29d3486247d78d94632d7fa499bc
Autor:
Giuseppina Chianese, Francesca Masi, Donatella Cicia, Daniele Ciceri, Sabrina Arpini, Mario Falzoni, Ester Pagano, Orazio Taglialatela-Scafati
Publikováno v:
Biomolecules, Vol 11, Iss 4, p 494 (2021)
A madecassoside-rich fraction obtained from the industrial purification of Centella asiatica leaves afforded a new triterpene glycoside, named isomadecassoside (4), characterized by an ursane-type skeleton and migration of the double bond at Δ20(21)
Externí odkaz:
https://doaj.org/article/5c8a170a625d41f5920c4d532fc8ed84
Autor:
Emiliano Manzo, Aniello Schiano Moriello, Francesco Tinto, Roberta Verde, Marco Allarà, Luciano De Petrocellis, Ester Pagano, Angelo A. Izzo, Vincenzo Di Marzo, Stefania Petrosino
Publikováno v:
Cells, Vol 10, Iss 2, p 450 (2021)
Palmitoylethanolamide (PEA) is an endogenous anti-inflammatory lipid mediator and a widely used nutraceutical. In this study, we designed, realized, and tested a drug-carrier conjugate between PEA (the active drug) and glucuronic acid (the carrier).
Externí odkaz:
https://doaj.org/article/fe521107ee0b450eb5f8063acaaf0966