Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Estelle Piwowar"'
Autor:
Jessica M. Fogel, Estelle Piwowar-Manning, Amber Moser, Tinia Hill, Shahnaz Ahmed, Vanessa Cummings, Heba H. Mostafa, Zhe Wang, Andrea Jennings, Jorge A. Gallardo-Cartagena, María Inés Figueroa, Marty St Clair, Alex R. Rinehart, Adeola Adeyeye, James F. Rooney, Myron S. Cohen, Beatriz Grinsztejn, Raphael J. Landovitz, Susan H. Eshleman
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT Detection of HIV infection may be challenging in persons using long-acting cabotegravir (CAB-LA) pre-exposure prophylaxis (PrEP) due to viral suppression and reduced/delayed antibody production. We evaluated two point-of-care tests for detec
Externí odkaz:
https://doaj.org/article/0ec30651f1934244afc8909a571ed9c4
Autor:
Stephen R Walsh, Cynthia L Gay, Shelly T Karuna, Ollivier Hyrien, Timothy Skalland, Kenneth H Mayer, Magdalena E Sobieszczyk, Lindsey R Baden, Paul A Goepfert, Carlos Del Rio, Guiseppe Pantaleo, Philip Andrew, Carissa Karg, Zonglin He, Huiyin Lu, Carmen A Paez, Jane A G Baumblatt, Laura L Polakowski, Wairimu Chege, Maija A Anderson, Sophie Janto, Xue Han, Yunda Huang, Julie Dumond, Margaret E Ackerman, Adrian B McDermott, Britta Flach, Estelle Piwowar-Manning, Kelly Seaton, Georgia D Tomaras, David C Montefiori, Lucio Gama, John R Mascola, HVTN 127/HPTN 087 Study Team
Publikováno v:
PLoS Medicine, Vol 21, Iss 6, p e1004329 (2024)
BackgroundBroadly neutralizing antibodies (bnAbs) are a promising approach for HIV-1 prevention. In the Antibody Mediated Prevention (AMP) trials, a CD4-binding site targeting bnAb, VRC01, administered intravenously (IV), demonstrated 75% prevention
Externí odkaz:
https://doaj.org/article/4be70ce338214ab0a34f240e9ededde1
Autor:
Jessica Justman, Timothy Skalland, Ayana Moore, Christopher I. Amos, Mark A. Marzinke, Sahar Z. Zangeneh, Colleen F. Kelley, Rebecca Singer, Stockton Mayer, Yael Hirsch-Moverman, Susanne Doblecki-Lewis, David Metzger, Elizabeth Barranco, Ken Ho, Ernesto T.A. Marques, Margaret Powers-Fletcher, Patricia J. Kissinger, Jason E. Farley, Carrie Knowlton, Magdalena E. Sobieszczyk, Shobha Swaminathan, Domonique Reed, Jean De Dieu Tapsoba, Lynda Emel, Ian Bell, Krista Yuhas, Leah Schrumpf, Laura Mkumba, Jontraye Davis, Jonathan Lucas, Estelle Piwowar-Manning, Shahnaz Ahmed
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 2, Pp 245-254 (2024)
During January–August 2021, the Community Prevalence of SARS-CoV-2 Study used time/location sampling to recruit a cross-sectional, population-based cohort to estimate SARS-CoV-2 seroprevalence and nasal swab sample PCR positivity across 15 US commu
Externí odkaz:
https://doaj.org/article/05b524e875824a568c8cba93369effc1
Autor:
Nomtha Bell-Mandla, Ethan Wilson, Deeksha Sharma, Rosa Sloot, Justin Bwalya, Ab Schaap, Deborah Donnell, Estelle Piwowar-Manning, Sian Floyd, Nozizwe Makola, Lungiswa Nkonki, Musonda Simwinga, Ayana Moore, Richard Hayes, Sarah Fidler, Helen Ayles, Peter Bock, the HPTN 071 (PopART) Study Team
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Introduction In 2021, there were 38.4 million people living with HIV (PLHIV) globally, of which 20.6 million (54%) were living in Eastern and Southern Africa. Longitudinal studies, inclusive of community randomized trials (CRTs), provide cri
Externí odkaz:
https://doaj.org/article/a41406ce49f74666981647962df56f9d
Autor:
Kostyantyn Dumchev, Xu Guo, Tran Viet Ha, Zubairi Djoerban, Oleksandr Zeziulin, Vivian F. Go, Riza Sarasvita, David S. Metzger, Carl A. Latkin, Scott M. Rose, Estelle Piwowar-Manning, Paul Richardson, Brett Hanscom, Kathryn E. Lancaster, William C. Miller, Irving F. Hoffman
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Introduction The HIV Prevention Trials Network (HPTN) 074 study demonstrated a positive effect of an integrated systems navigation and psychosocial counseling intervention on HIV treatment initiation, viral suppression, medication assisted t
Externí odkaz:
https://doaj.org/article/11f84e8cf4cf456fac52905c6144b639
Autor:
Wendy Grant‐McAuley, Estelle Piwowar‐Manning, William Clarke, Autumn Breaud, Kidist Belay Zewdie, Ayana Moore, Helen Mary Ayles, Barry Kosloff, Kwame Shanaube, Peter Bock, Sue‐Ann Meehan, Gerald Maarman, Sarah Fidler, Richard Hayes, Deborah Donnell, Susan H. Eshleman, for the HPTN 071 (PopART) Study Team
Publikováno v:
Journal of the International AIDS Society, Vol 26, Iss 10, Pp n/a-n/a (2023)
Abstract Introduction HIV controllers have low viral loads (VL) without antiretroviral treatment (ART). We evaluated viraemic control in a community‐randomized trial conducted in Zambia and South Africa that evaluated the impact of a combination pr
Externí odkaz:
https://doaj.org/article/b2c0c8c3efe346ffbdaed8b6335fa7d5
Autor:
Wendy Grant-McAuley, William Morgenlander, Sarah E. Hudelson, Manjusha Thakar, Estelle Piwowar-Manning, William Clarke, Autumn Breaud, Joel Blankson, Ethan Wilson, Helen Ayles, Peter Bock, Ayana Moore, Barry Kosloff, Kwame Shanaube, Sue-Ann Meehan, Anneen van Deventer, Sarah Fidler, Richard Hayes, Ingo Ruczinski, Kai Kammers, Oliver Laeyendecker, H. Benjamin Larman, Susan H. Eshleman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundHigh HIV viral load (VL) is associated with increased transmission risk and faster disease progression. HIV controllers achieve viral suppression without antiretroviral (ARV) treatment. We evaluated viremic control in a community-randomized
Externí odkaz:
https://doaj.org/article/3769d3f9e6b24fc1a64b70c5aea7e75e
Autor:
Wendy Grant-McAuley, Oliver Laeyendecker, Daniel Monaco, Athena Chen, Sarah E. Hudelson, Ethan Klock, Ron Brookmeyer, Douglas Morrison, Estelle Piwowar-Manning, Charles S. Morrison, Richard Hayes, Helen Ayles, Peter Bock, Barry Kosloff, Kwame Shanaube, Nomtha Mandla, Anneen van Deventer, Ingo Ruczinski, Kai Kammers, H. Benjamin Larman, Susan H. Eshleman
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Multi-assay algorithms (MAAs) are used to estimate population-level HIV incidence and identify individuals with recent infection. Many MAAs use low viral load (VL) as a biomarker for long-term infection. This could impact incidenc
Externí odkaz:
https://doaj.org/article/d4fff91866cb44c7b477c8dbd3236eaa
Autor:
Michael Pickles, Anne Cori, William J M Probert, Rafael Sauter, Robert Hinch, Sarah Fidler, Helen Ayles, Peter Bock, Deborah Donnell, Ethan Wilson, Estelle Piwowar-Manning, Sian Floyd, Richard J Hayes, Christophe Fraser, HPTN 071 (PopART) Study Team
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 9, p e1009301 (2021)
Mathematical models are powerful tools in HIV epidemiology, producing quantitative projections of key indicators such as HIV incidence and prevalence. In order to improve the accuracy of predictions, such models need to incorporate a number of behavi
Externí odkaz:
https://doaj.org/article/affef60ff94443cda079aebd0c49e70c
Autor:
Wendy Grant-McAuley, Ethan Klock, Oliver Laeyendecker, Estelle Piwowar-Manning, Ethan Wilson, William Clarke, Autumn Breaud, Ayana Moore, Helen Ayles, Barry Kosloff, Kwame Shanaube, Peter Bock, Nomtha Mandla, Anneen van Deventer, Sarah Fidler, Deborah Donnell, Richard Hayes, Susan H Eshleman, HPTN 071 (PopART) Study Team
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0258644 (2021)
BackgroundAssays and multi-assay algorithms (MAAs) have been developed for population-level cross-sectional HIV incidence estimation. These algorithms use a combination of serologic and/or non-serologic biomarkers to assess the duration of infection.
Externí odkaz:
https://doaj.org/article/46c30877e7234a9b85c9c295c05d76f5