Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Estelle M.-N. Hamelin"'
Autor:
Stephen Martin Courtney, Suganthan Selvaratnam, Christopher John Yarnold, Paolo Tavecchia, Mirco Meniconi, Carlo Riva, Estelle M. N. Hamelin, Helen S. Boehm, Raffaella Di Lucrezia, David Willows, Paul Giles, J. Marie Bainbridge, Jörn Jungmann, Sakthi Shanmugathasan, Hervé Deboves, Giorgio Sironi, Amedeo Leonardi, Mark Brewer, Andreas Scheel
Publikováno v:
ChemistrySelect. 2:175-189
The development of selective steroidal mineralocorticoid receptor antagonists with improved pharmacological profiles over existing marketed drugs is an attractive goal. Such compounds offer potential for the treatment of hypertension, heart failure a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af79ddb420ff0b9e5a5a67776da72d18
https://doi.org/10.1002/slct.201601744
https://doi.org/10.1002/slct.201601744
Autor:
John J. Barker, Saverio Minucci, Roberto Boggio, Mario Varasi, Osamu Ichihara, Thomas Hesterkamp, Annett Müller, Mark Whittaker, Stephen Martin Courtney, Mihaly Gardiner, Oliver Barker, Banu G. Phillips, Vincent Anthony Corden, Christian Aldo Georges Napoleon Montalbetti, Christopher John Yarnold, Estelle M. N. Hamelin, Fulvia Fusar, Deepti Patel, Owen Mather, Viddhata Chauhan, Robert K. Y. Cheng, Dirk Winkler, Neil Edwards, Virginie M. Falque, Richard S. Jones, Ciro Mercurio
Publikováno v:
ChemMedChem. 4:963-966
Heat shock protein 90 (Hsp90) plays a key role in stress response and protection of the cell against the effects of mutation. Herein we report the identification of an Hsp90 inhibitor identified by fragment screening using a high-concentration bioche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::790471e2675386bf20d58b19efd0bb16
https://doi.org/10.1002/cmdc.200900011
https://doi.org/10.1002/cmdc.200900011
Autor:
William N. Draffin, Michael G. B. Drew, Laurence M. Harwood, Estelle M.-N. Hamelin, David J. Aldous, Sukanthini Thurairatnam
Publikováno v:
Synthesis. :3271-3278
We report herein, the first generation of unsymmetrical ketone-derived chiral stabilized azomethine ylides. Intrairiolecular and intermolecular cycloaddition strategies have been utilized to synthesize both an enantiornerically pure bicyclic proline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::900b5228b97dd8e8179a526ba8ea2bf6
https://doi.org/10.1055/s-2005-918487
https://doi.org/10.1055/s-2005-918487
Autor:
Michael G. B. Drew, Archie B. Jahans, Sukanthini Thurairatnam, Laurence M. Harwood, Estelle M.-N. Hamelin, David J. Aldous
Publikováno v:
Synlett. 2001:1836-1840
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::525efb967e4ff36c707002f9cf81aa8e
https://doi.org/10.1055/s-2001-18762
https://doi.org/10.1055/s-2001-18762
Publikováno v:
Synlett. 2001:1841-1842
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::226e7450a171632a9724d535f1b087c9
https://doi.org/10.1055/s-2001-18763
https://doi.org/10.1055/s-2001-18763
Autor:
Barker, John J., Barker, Oliver, Boggio, Roberto, Chauhan, Viddhata, Cheng, Robert K. Y., Corden, Vincent, Courtney, Stephen M., Edwards, Neil, Falque, Virginie M., Fusar, Fulvia, Gardiner, Mihaly, Hamelin, Estelle M. N., Hesterkamp, Thomas, Ichihara, Osamu, Jones, Richard S., Mather, Owen, Mercurio, Ciro, Minucci, Saverio, Montalbetti, Christian A. G. N., Müller, Annett
Publikováno v:
ChemMedChem; 2009, Vol. 4 Issue 6, p963-966, 4p
Autor:
Aldous, David J., Drew, Michael G. B., Hamelin, Estelle M.-N., Harwood, Laurence M., Jahans, Archie B., Thurairatnam, Sukanthini
Publikováno v:
Synlett; 2001, Vol. 2001 Issue 12, p1836-1840, 5p
Publikováno v:
Synlett; 2001, Vol. 2001 Issue 12, p1841-1842, 2p