Lysine Scanning of Arg10–Teixobactin: Deciphering the Role of Hydrophobic and Hydrophilic Residues

Autor: Shimaa A. H. Abdel Monaim, Yahya E. Jad, Estelle J. Ramchuran, Ayman El-Faham, Thavendran Govender, Hendrik G. Kruger, Beatriz G. de la Torre, Fernando Albericio

Publikováno v: ACS Omega, Vol 1, Iss 6, Pp 1262-1265 (2016)

Externí odkaz: https://doaj.org/article/d0da3c85d6b4482c9cf43c844e11269d

Structure-Activity Relationship of Arg10-Teixobactin: A Recently Discovered Antimicrobial Peptide

Autor: Fernando Albericio, Shimaa A. H. Abdel Monaim, Yahya E. Jad, Gerardo A. H. Acosta, Estelle J. Ramchuran, Ayman El-Faham, Thavendran Govender, Hendrik G. Kruger, Beatriz G. de la Torre

Publikováno v: Proceedings, Vol 1, Iss 6, p 671 (2017)

The emergence of multidrug resistant bacteria has a direct impact on global public health due to the reduced potency of existing antibiotics against pathogens [1]. [...]

Externí odkaz: https://doaj.org/article/c897f2cd6696438189c8b53368841ec0

Super-Cationic Peptide Dendrimers—Synthesis and Evaluation as Antimicrobial Agents

Autor: Rene B Khan, Linda A. Bester, Beatriz G. de la Torre, Estelle J. Ramchuran, Miguel Viñas, Fernando Albericio, Isabel Pérez-Guillén

Publikováno v: Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Antibiotics
Volume 10
Issue 6
Dipòsit Digital de la UB
Universidad de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC
instname
Antibiotics, Vol 10, Iss 695, p 695 (2021)

Microbial infections are a major public health concern. Antimicrobial peptides (AMPs) have been demonstrated to be a plausible alternative to the current arsenal of drugs that has become inefficient due to multidrug resistance. Herein we describe a n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110868d48a620fbfb6228b425c1d6c5b

Re-evaluation of the N-terminal substitution and the D-residues of teixobactin

Autor: Ayman El-Faham, Yahya E. Jad, Tricia Naicker, Estelle J. Ramchuran, Beatriz G. de la Torre, Thavendran Govender, Hendrik G. Kruger, Gerardo A. Acosta, Fernando Albericio, Shimaa A. H. Abdel Monaim

Publikováno v: RSC Advances. 6:73827-73829

Teixobactin is a head to side-chain cyclic depsipeptide with a guanidino based residue within the cycle, three D-amino acids in the tail, and a N-methylated terminal residue. The synthesis of the first analogue, containing Arg, was recently described

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c564cfccfaf84b81cc825b1adbfe59de
https://doi.org/10.1039/c6ra17720d

Investigation of the N-terminus amino functional of Arg10-Teixobactin

Autor: Sikabwe Noki, Fernando Albericio, Ayman El-Faham, Estelle J. Ramchuran, Beatriz G. de la Torre, Shimaa A. H. Abdel Monaim

Publikováno v: Molecules, Vol 22, Iss 10, p 1632 (2017)
Dipòsit Digital de la UB
Universidad de Barcelona

Teixobactin is a recently described antimicrobial peptide that shows high activity against gram-positive bacteria as well as mycobacterium tuberculosis. Due to both its structure as a head-to-side chain cyclodepsipeptide and its activity, it has attr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab9deb550131e85f5b07251d472b952
http://hdl.handle.net/2445/155311