Výsledky vyhledávání - "Estelle Grasset"

272-OR: Weight Loss with Time-Restricted Feeding or Treatment with Obeticholic Acid/Semaglutide Combination Have a Different Impact on Nonalcoholic Steatohepatitis in Diet-Induced Obese Mice

Autor: FRANCOIS BRIAND, ESTELLE GRASSET, NATALIA BREYNER, THIERRY SULPICE

Publikováno v: Diabetes. 71

Introduction: Combination of therapies is a promising strategy for the treatment of NASH and liver fibrosis. Here we evaluated whether the Farnesoid X Receptor agonist obeticholic acid (OCA) combined with the glucagon-like peptide-1 (GLP-1) receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::acd408844a41fbf00f3e9f9e8d0661bf
https://doi.org/10.2337/db22-272-or

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Weight loss with semaglutide treatment or time-restricted feeding differentially improves non-alcoholic steatohepatitis in diet-induced obese insulin resistant mice

Autor: Francois Briand, Estelle Grasset, Natalia Breyner, Thierry Sulpice

Publikováno v: Journal of Hepatology. 77:S717

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9eb83a29ebbb550baee43fdec4e7f71b
https://doi.org/10.1016/s0168-8278(22)01752-4

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Gut microbiota dysbiosis of type 2 diabetic mice impairs the intestinal daily rhythms of GLP-1 sensitivity

Autor: Estelle Grasset, Rémy Burcelin, Florence Servant, Jeffrey E. Christensen, Vincent Blasco-Baque, Anthony Puel, Pascale Klopp, Benjamin Lelouvier, Julie Charpentier, François Tercé

Publikováno v: Acta diabetologica. 59(2)

The gut–brain–beta cell glucagon-like peptide-1 (GLP-1)-dependent axis and the clock genes both control insulin secretion. Evidence shows that a keystone of this molecular interaction could be the gut microbiota. We analyzed in mice the circadian

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21003e97c7311053d62b267077cb6b04
https://pubmed.ncbi.nlm.nih.gov/34648088

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Lixisenatide requires a functional gut-vagus nerve-brain axis to trigger insulin secretion in controls and type 2 diabetic mice

Autor: Aurélie Waget, Pascale Klopp, Rémy Burcelin, Shin J. Lee, Céline Cruciani-Guglielmacci, Estelle Grasset, Christophe Magnan, Julie Charpentier

Publikováno v: AJP-Gastrointestinal and Liver Physiology
AJP-Gastrointestinal and Liver Physiology, American Physiological Society, 2018, 315 (5), pp.G671-G684. ⟨10.1152/ajpgi.00348.2017⟩
AJP-Gastrointestinal and Liver Physiology, 2018, 315 (5), pp.G671-G684. ⟨10.1152/ajpgi.00348.2017⟩

Endogenous glucagon-like peptide-1 (GLP-1) regulates glucose-induced insulin secretion through both direct β-cell-dependent and indirect gut-brain axis-dependent pathways. However, little is known about the mode of action of the GLP-1 receptor agoni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ffdb9ed4278a89724a86a60ce07f6a
https://doi.org/10.1152/ajpgi.00348.2017

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The gut microbiota to the brain axis in the metabolic control

Autor: Estelle Grasset, Rémy Burcelin

Publikováno v: Reviews in Endocrine & Metabolic Disorders

The regulation of glycemia is under a tight neuronal detection of glucose levels performed by the gut-brain axis and an efficient efferent neuronal message sent to the peripheral organs, as the pancreas to induce insulin and inhibit glucagon secretio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1c70ff003c02dedbc589e914e5180a4
https://pubmed.ncbi.nlm.nih.gov/31656993

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Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks

Autor: Filipe, De Vadder, Estelle, Grasset, Louise, Mannerås Holm, Gérard, Karsenty, Andrew J, Macpherson, Louise E, Olofsson, Fredrik, Bäckhed

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 115(25)

The enteric nervous system (ENS) is crucial for essential gastrointestinal physiologic functions such as motility, fluid secretion, and blood flow. The gut is colonized by trillions of bacteria that regulate host production of several signaling molec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4ea52ed6c41b691c3d9a1ddb3905b39c
https://pubmed.ncbi.nlm.nih.gov/29934558

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Oral health and microbiota status in professional rugby players: A case-control study

Autor: Jean-Michel Loubes, Jean-Noel Vergnes, François Tercé, Matthieu Minty, Estelle Grasset, Thibault Canceill, Pascale Loubieres, Oihana Amestoy, Sylvie Lê, Matteo Serino, Vincent Azalbert, Jean-Philippe Mallet, Jeffrey E. Christensen, Franck Diemer, Vincent Blasco-Baque, Camille Champion, Sara Hardy, Rémy Burcelin, Pauline Dubois

Publikováno v: Journal of Dentistry
Journal of Dentistry, Elsevier, 2018, 79, pp.53-60. ⟨10.1016/j.jdent.2018.10.001⟩
Journal of Dentistry, 2018, 79, pp.53-60. ⟨10.1016/j.jdent.2018.10.001⟩

Objective Elite athletes are prone to develop oral diseases, which could increase the risk for injuries. The aim of this study was to evaluate the oral health and the composition of oral microbiota of elite rugby players compared to the general popul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff60b96b26dcb64ac6df8d1ed8ccbe8a
https://hal.inrae.fr/hal-02624123

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VIP receptors and control of short circuit current in the human intestinal clonal cell line Cl.19A

Autor: Estelle Grasset, Christian L. Laboisse, Chantal Augeron, Marc Laburthe, Christiane Rouyer-Fessard, Jean-José Maoret

Publikováno v: Experientia. 45(11-12)

At the maximally effective concentration of 10 nM, VIP induced a marked (12.5-fold stimulation above basal), and sustained increase in short circuit current in the human intestinal epithelial cell line Cl.19A grown on permeable filters and placed in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a38c544d55086004c1d3965be07ce0e
https://pubmed.ncbi.nlm.nih.gov/2557231

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Functional VIP receptors in the human mucus-secreting colonic epithelial cell line CL.16E

Autor: Christiane Rouyer-Fessard, Jean-José Maoret, Marc Laburthe, Chantal Augeron, Estelle Grasset, Christian L. Laboisse, I. Roumagnac

Publikováno v: The American journal of physiology. 256(3 Pt 1)

A polarized human clonal intestinal cell line exhibiting mucus secretion (Cl.16E) was used to study the expression and function of vasoactive intestinal peptide (VIP) receptors in mucus-secreting cells. Cl.16E cells expressed one class of receptors w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b5d9bf4e604c81396576d4a41a37ac0
https://pubmed.ncbi.nlm.nih.gov/2538074

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