Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Estelle Espinos"'
Publikováno v:
Cells, Vol 10, Iss 10, p 2517 (2021)
Autophagy has been described as harboring a dual role in cancer development and therapy. Depending on the context, it can exert either pro-survival or pro-death functions. Here, we review what is known about autophagy in crizotinib-treated ALK+ ALCL.
Externí odkaz:
https://doaj.org/article/df0eeb0e208a434abd297539ebfa4a4b
Autor:
Avedis Torossian, Nicolas Broin, Julie Frentzel, Camille Daugrois, Sarah Gandarillas, Talal Al Saati, Laurence Lamant, Pierre Brousset, Sylvie Giuriato, Estelle Espinos
Publikováno v:
Haematologica, Vol 104, Iss 7 (2019)
Anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphomas are tumors that carry translocations involving the ALK gene at the 2p23 locus, leading to the expression of ALK tyrosine kinase fusion oncoproteins. Amongst hematologic maligna
Externí odkaz:
https://doaj.org/article/1831c4e98edc4fd089548918768653f1
Autor:
Estelle Espinos, Dominique Morello, Georges Delsol, Laurence Lamant, Cecile Desjobert, Celine Lopez, Mohamad Fawal, Julie Bergalet
The CCAAT/enhancer-binding protein β (C/EBPβ) plays a major role in the pathogenesis of anaplastic large cell lymphomas (ALCL) that express the nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) tyrosine kinase (ALK+). Although ALK-mediated C/EBPβ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9f844ce8d81b2766a9413fc8588579
https://doi.org/10.1158/1541-7786.c.6542326.v1
https://doi.org/10.1158/1541-7786.c.6542326.v1
Autor:
Lamant, Camille Daugrois, Chloé Bessiere, Sébastien Dejean, Véronique Anton-Leberre, Thérèse Commes, Stephane Pyronnet, Pierre Brousset, Estelle Espinos, Laurence Brugiere, Fabienne Meggetto, Laurence
Publikováno v:
Cancers; Volume 13; Issue 21; Pages: 5523
Anaplastic large cell lymphomas associated with ALK translocation have a good outcome after CHOP treatment; however, the 2-year relapse rate remains at 30%. Microarray gene-expression profiling of 48 samples obtained at diagnosis was used to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::a2b6d785c002a2a634ed77a37d6cca13
Autor:
Estelle Espinos
Publikováno v:
Annales de Pathologie. 28:S71-S76
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fbb2306d7899b222a708a4220ab69fc
https://doi.org/10.1016/j.annpat.2008.09.022
https://doi.org/10.1016/j.annpat.2008.09.022
Publikováno v:
Frontiers in bioscience (Landmark edition). 20(8)
Extensive research has been carried out in the past two decades to provide insights into the molecular mechanisms by which the Nucleophosmin-Anaplastic Lymphoma Kinase (NPM-ALK) exerts its oncogenic effects. These studies led to the concept that NPM-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf8a5436d9db77cfc81916c17b0dfc1
https://pubmed.ncbi.nlm.nih.gov/25961555
https://pubmed.ncbi.nlm.nih.gov/25961555
Autor:
Bernard Monsarrat, Audrey Colomba, Frédérique Gaits-Iacovoni, Frédéric Pont, Estelle Espinos, Florence Capilla, Carole Pichereaux, Odile Burlet-Schiltz, Laurence Lamant, Georges Delsol, Bernard Payrastre, Daniel Cussac
Publikováno v:
PROTEOMICS. 6:3210-3222
Anaplastic large-cell lymphomas (ALCL) are high grade lymphomas of T or null phenotype often associated with the t(2;5) translocation leading to the expression of a chimeric protein consisting of the N-terminal portion of nucleophosmin (NPM) and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a310a072fef3cbbef5489bb890075326
https://doi.org/10.1002/pmic.200500647
https://doi.org/10.1002/pmic.200500647
Autor:
Laurence Lamant, Randy D. Gascoyne, Michèle Allouche, T. Al Saati, Claire Villalva, J Ragab, Nicole Dastugue, Marie-Michèle Duplantier, Estelle Espinos, Pierre Brousset, Alain Robert, Georges Delsol
Publikováno v:
Leukemia. 18:1693-1698
Anaplastic large-cell lymphoma (ALCL) is a distinct biological and cytogenetic entity with a broad spectrum of morphological features (common type, small-cell variant and lymphohistiocytic variant). Few cell lines of ALCL are available and they all o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2d412a99032a42b353439f8ed5d78e
https://doi.org/10.1038/sj.leu.2403464
https://doi.org/10.1038/sj.leu.2403464
Autor:
Nancy L. Harris, Douglas E. Horsman, Randy D. Gascoyne, Georges Delsol, Laurence Lamant, John F. Seymour, Estelle Espinos, Isabelle Auvigne, Hans Konrad Müller-Hermelink, Reiner Siebert, José I. Martín-Subero, Lynda J. Campbell, Valia S. Lestou
Publikováno v:
Blood. 102:2568-2573
Expression of ALK protein by lymphoid cells and the description of variant anaplastic lymphoma kinase (ALK) translocations have typically been restricted to cases of T-cell and null anaplastic large-cell lymphoma (ALCL). All such cases result from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f545d94bbeda713807ee54b867db25da
https://doi.org/10.1182/blood-2003-03-0786
https://doi.org/10.1182/blood-2003-03-0786
Autor:
Estelle Espinos, Mukesh Chhanabhai, Florence Armstrong, Randy D. Gascoyne, Evica Rajcan-Separovic, Marie Michèle Duplantier, Janie Raghab, Laurence Lamant, Georges Delsol, Ashraf Raghab
Publikováno v:
Genes, Chromosomes and Cancer. 37:427-432
In anaplastic large cell lymphoma, the ALK gene at 2p23 is known to be fused to NPM, TPM3, TPM4, TFG, ATIC, CLTC, MSN, and ALO17. All of these translocations result in the expression of chimeric ALK transcripts that are translated into fusion protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e4ab6c1e296965606e81d8a62daaec
https://doi.org/10.1002/gcc.10232
https://doi.org/10.1002/gcc.10232