Artificial intelligence for solid tumour diagnosis in digital pathology

Autor: Maria Chiara Maiuri, Julien Calderaro, Nicolas Loménie, Estelle Devevre, Christophe Klein, Floriane Arbaretaz, Qinghe Zeng

Publikováno v: British journal of pharmacologyREFERENCES. 178(21)

Tumour diagnosis relies on the visual examination of histological slides by pathologists through a microscope eyepiece. Digital pathology, the digitalization of histological slides at high magnification with slides scanners, has raised the opportunit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99065a95b662e2be17f449fd2622cb0a
https://pubmed.ncbi.nlm.nih.gov/34302297

Enhanced cytotoxicity and decreased CD8 dependence of human cancer-specific cytotoxic T lymphocytes after vaccination with low peptide dose

Autor: Philippe Guillaume, Nathalie Rufer, Petra Baumgaertner, Daniel E. Speiser, Tanja Lövgren, Sébastien Wieckowski, Estelle Devevre, Immanuel F. Luescher

Publikováno v: Cancer immunology immunotherapy : CII
Cancer Immunology, Immunotherapy
Cancer Immunology, Immunotherapy, Springer Verlag, 2012, 61 (6), pp.817-826. ⟨10.1007/s00262-011-1140-1⟩
Cancer Immunology, Immunotherapy, vol. 61, no. 6, pp. 817-826

International audience; In mice, vaccination with high peptide doses generates higher frequencies of specific CD8+ T cells, but with lower avidity compared to vaccination with lower peptide doses. To investigate the impact of peptide dose on CD8+ T c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1521b0ac58433d34d42c4436bc2f13fb

Memory and Effector CD8 T-cell Responses After Nanoparticle Vaccination of Melanoma Patients

Autor: Christine Geldhof, Uwe Trefzer, Katrin Baumann Conzett, Daniel E. Speiser, Verena Voelter, Alexander Knuth, Peter Walden, Reinhard Dummer, Katrin Schwarz, Jörg Willers, Alfred Zippelius, Pedro Romero, Thomas M. Kündig, Gabriela Senti, Estelle Devevre, Vania Manolova, Petra Baumgaertner, David Guggisberg, Martin F. Bachmann, Wolfram Sterry, Jean Philippe Cerottini

Publikováno v: Journal of Immunotherapy
Journal of Immunotherapy, Lippincott, Williams & Wilkins, 2010, 33 (8), pp.848-858. ⟨10.1097/CJI.0b013e3181f1d614⟩

International audience; Induction of cytotoxic CD8 T-cell responses is enhanced by the exclusive presentation of antigen through dendritic cells, and by innate stimuli, such as toll-like receptor ligands. On the basis of these 2 principles, we design

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ede4eec93de40bd8474622f8cf09db9
https://doi.org/10.1097/cji.0b013e3181f1d614

Profiling of the Three Circulating Monocyte Subpopulations in Human Obesity

Autor: Isabelle Cremer, Mariana Renovato-Martins, Catherine Sautès-Fridman, Karine Clément, Estelle Devevre, Christine Poitou

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2015, 194 (8), pp.3917-3923. ⟨10.4049/jimmunol.1402655⟩
Journal of Immunology, 2015, 194 (8), pp.3917-3923. ⟨10.4049/jimmunol.1402655⟩

Three subpopulations of circulating monocytes have been described: CD142+CD16− (classical monocytes [CM]), CD142+CD16+ (intermediate monocytes [IM]), and CD14+CD162+ (nonclassical monocytes [NCM]). We previously showed that obesity is associated wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7b30e7df49ee02785c61abc2deac5a
https://hal.archives-ouvertes.fr/hal-02542009

Differentiation associated regulation of microRNA expression in vivo in human CD8+ T cell subsets

Autor: Yasuko Tsunetsugu-Yokota, Antoine Roux, Petra Baumgaertner, Philippe Martiat, Marion Braun, Brigitte Autran, Pedro Romero, Lukas Baitsch, Daniel E. Speiser, Estelle Devevre, Takuya Yamamoto, Victor Appay, Anirudh Ramesh, Bassam Badran, Hussein Fayyad-Kazan, Bruno Salaun, Redouane Rouas

Publikováno v: Journal of Translational Medicine
Journal of Translational Medicine, BioMed Central, 2011, 9 (1), pp.44. ⟨10.1186/1479-5876-9-44⟩
Journal of translational medicine, 9
Journal of Translational Medicine, Vol 9, Iss 1, p 44 (2011)
Journal of Translational Medicine, 2011, 9 (1), pp.44. ⟨10.1186/1479-5876-9-44⟩
Journal of Translational Medicine, vol. 9, pp. 44

The differentiation of CD8+ T lymphocytes following priming of naïve cells is central in the establishment of the adaptive immune response. Yet, the molecular events underlying this process are not fully understood. MicroRNAs have been recently show

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3c955ee6ace3324f5cd31cc662df19
https://pubmed.ncbi.nlm.nih.gov/21507256