Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Estelle Bajtner"'
Autor:
Estelle Bajtner, Rikard Holmdahl, Hongwei Jia, John A. Mo, Kutty Selva Nandakumar, Thomas Blom, Ia Khmaladze, Duojia Cao
Publikováno v:
The Journal of Immunology. 187:4451-4458
We have addressed the importance of B cell tolerance to collagen type II, a matrix protein, which is a target in rheumatoid arthritis (RA) and its mouse models. We generated a germline-encoded anti-collagen type II (CII) IgH replacement anti-C1 B cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4656d2d8a93052c4d5844d6342d467b0
https://doi.org/10.4049/jimmunol.1101378
https://doi.org/10.4049/jimmunol.1101378
Autor:
Beate Böhm, Merrill J. Rowley, Kutty Selva Nandakumar, Leigh Raymond Hill, Harald Burkhardt, Rikard Holmdahl, Estelle Bajtner
Publikováno v:
Arthritis & Rheumatism. 58:184-196
OBJECTIVE: To investigate the significance and pathogenic potential of a highly conserved major type II collagen triple-helical epitope-specific antibody (U1; amino acids 494-504) in vivo and in vitro in patients with early rheumatoid arthritis (RA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a6a5fd025338beb8f01b644681e432
https://doi.org/10.1002/art.23049
https://doi.org/10.1002/art.23049
Autor:
Franziska Lange, Carola Rintisch, Kutty Selva Nandakumar, Rikard Holmdahl, Ulrich Sack, Estelle Bajtner
Publikováno v:
Annals of the Rheumatic Diseases. 64:599-605
Objective: To investigate the mode of action of methotrexate (MTX) in different types of models for rheumatoid arthritis (RA) and multiple sclerosis (MS). Methods: Models for RA and MS were selected known to have different pathogenesis—that is, fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d536fb3cc7a8959eabce0b0b7da5b2aa
https://doi.org/10.1136/ard.2004.026120
https://doi.org/10.1136/ard.2004.026120
Autor:
Estelle Bajtner, Rikard Holmdahl, O Zaether, Andrej Tarkowski, I. M. Jonsson, Margareta Verdrengh
Publikováno v:
Annals of the Rheumatic Diseases; 61(9), pp 829-831 (2002)
BACKGROUND: Collagen-induced arthritis (CIA) is the most commonly used model of rheumatoid arthritis (RA). In both CIA and RA there is an increase in the cellular content of the synovium, this being dominated by macrophages. OBJECTIVE: To assess the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df2a891a37638a422672710f6986f8d2
https://doi.org/10.1136/ard.61.9.829
https://doi.org/10.1136/ard.61.9.829
Autor:
Åke Engström, Kutty Selva Nandakumar, Estelle Bajtner, Harald Burkhardt, Bettina Sehnert, Rikard Holmdahl, Hüseyin Uysal, Marjolein M. G. M. Thunnissen, Guy Serre, Robert Bockermann
Publikováno v:
Journal of Experimental Medicine; 206(2), pp 449-462 (2009)
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Antibodies to citrulline-modified proteins have a high diagnostic value in rheumatoid arthritis (RA). However, their biological role in disease development is still unclear. To obtain insight into this question, a panel of mouse monoclonal antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b9dda472e5b80aa7083d5e327fcec2
https://lup.lub.lu.se/record/1302751
https://lup.lub.lu.se/record/1302751
Publikováno v:
International immunology. 13(7)
Collagen-induced arthritis (CIA) is a widely used model for rheumatoid arthritis. Induction of CIA in rats using rat type II collagen (CII) results in a chronic arthritis in which anti-CII antibodies are believed to play a pathogenic role. In this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98b4f543e781cb3c206b3ab9f752b282
https://pubmed.ncbi.nlm.nih.gov/11431421
https://pubmed.ncbi.nlm.nih.gov/11431421
Autor:
Thomas Blom, Hongwei Jia, Ia Khmaladze, Duojia Cao, John A. Mo, Rikard Holmdahl, Kutty Selva Nandakumar, Estelle Bajtner
Publikováno v:
The Journal of Immunology. 189:3263-3263
Cao, D., I. Khmaladze, H. Jia, E. Bajtner, K. S. Nandakumar, T. Blom, J. A. Mo, and R. Holmdahl. 2011. Pathogenic autoreactive B cells are not negatively selected toward matrix protein collagen II. J Immunol . 187: [4451–4458][1]. There were severa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b61ebec33baa467143f0fb4f02e03fb
https://doi.org/10.4049/jimmunol.1290049
https://doi.org/10.4049/jimmunol.1290049
Publikováno v:
Arthritis Research & Therapy. 7:R1148
Antibodies against type II collagen (CII) are important in the development of collagen-induced arthritis (CIA) and possibly also in rheumatoid arthritis. We have determined the fine specificity and arthritogenicity of the antibody response to CII in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b87329a406a4fd548a8e085103bd9cd1
https://doi.org/10.1186/ar1800
https://doi.org/10.1186/ar1800