Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Estelle, Nicolas"'
Autor:
Mathéa Geraud, Agnese Cristini, Simona Salimbeni, Nicolas Bery, Virginie Jouffret, Marco Russo, Andrea Carla Ajello, Lara Fernandez Martinez, Jessica Marinello, Pierre Cordelier, Didier Trouche, Gilles Favre, Estelle Nicolas, Giovanni Capranico, Olivier Sordet
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114214- (2024)
Summary: TDP1 removes transcription-blocking topoisomerase I cleavage complexes (TOP1ccs), and its inactivating H493R mutation causes the neurodegenerative syndrome SCAN1. However, the molecular mechanism underlying the SCAN1 phenotype is unclear. He
Externí odkaz:
https://doaj.org/article/d37f0288c1ca4085bf68d93fbf8946d1
Autor:
Lee S. Nguyen, Marion Helias, Lisa Raia, Estelle Nicolas, Paul Jaubert, Sarah Benghanem, Zakaria Ait Hamou, Pierre Dupland, Julien Charpentier, Frédéric Pène, Alain Cariou, Jean-Paul Mira, Jean-Daniel Chiche, Mathieu Jozwiak
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Managing patients with acute respiratory distress syndrome (ARDS) requires frequent changes in mechanical ventilator respiratory settings to optimize arterial oxygenation assessed by arterial oxygen partial pressure (PaO2) and saturation (Sa
Externí odkaz:
https://doaj.org/article/ce502eb9c86b4cb2bc6ad752b50eb024
Autor:
Huifen Cao, Dongyang Xu, Ye Cai, Xueer Han, Lu Tang, Fan Gao, Yao Qi, DingDing Cai, Huifang Wang, Maxim Ri, Denis Antonets, Yuri Vyatkin, Yue Chen, Xiang You, Fang Wang, Estelle Nicolas, Philipp Kapranov
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-24 (2021)
Abstract Background The majority of the human genome is transcribed in the form of long non-coding (lnc) RNAs. While these transcripts have attracted considerable interest, their molecular mechanisms of function and biological significance remain con
Externí odkaz:
https://doaj.org/article/f8c11f8e08bb498fa81fb30c0f58843e
Autor:
Assala Lamaa, Jonathan Humbert, Marion Aguirrebengoa, Xue Cheng, Estelle Nicolas, Jacques Côté, Didier Trouche
Publikováno v:
eLife, Vol 9 (2020)
The H2A.Z histone variant plays major roles in the control of gene expression. In human, H2A.Z is encoded by two genes expressing two isoforms, H2A.Z.1 and H2A.Z.2 differing by three amino acids. Here, we undertook an integrated analysis of their fun
Externí odkaz:
https://doaj.org/article/2cde7cb03c184f46ad60c0bf8a3aa3e3
Autor:
Lisa Muniz, Maharshi Krishna Deb, Marion Aguirrebengoa, Sandra Lazorthes, Didier Trouche, Estelle Nicolas
Publikováno v:
Cell Reports, Vol 21, Iss 9, Pp 2433-2446 (2017)
Antisense RNAs are non-coding RNAs that can regulate their corresponding sense RNAs and are generally produced from specific promoters. We uncover here a family of antisense RNAs, named START RNAs, produced during cellular senescence by transcription
Externí odkaz:
https://doaj.org/article/533e71cf6e98427b94058de81f604d16
Publikováno v:
Molecular and Cellular Biology. 42
Transcriptional gene silencing by small interfering RNAs (siRNAs) has been widely described in various species, including plants and yeast. In mammals, its extent remains somewhat debated. Previous studies showed that siRNAs targeting gene promoters
Transcriptional gene silencing by small interfering RNAs (siRNAs) has been widely described in various species, such as plants or fission yeasts. In mammals, its extent remained somewhat debated. Previous studies showed that siRNAs targeting gene pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef6f8cfddeb7d96a55f81391710a9437
https://doi.org/10.1101/2022.05.11.491477
https://doi.org/10.1101/2022.05.11.491477
Publikováno v:
The EMBO Journal
EMBO Journal
EMBO Journal, EMBO Press, 2021, 40 (15), ⟨10.15252/embj.2020105740⟩
EMBO Journal
EMBO Journal, EMBO Press, 2021, 40 (15), ⟨10.15252/embj.2020105740⟩
RNA polymerase II (RNA Pol II) speed or elongation rate, i.e., the number of nucleotides synthesized per unit of time, is a major determinant of transcriptome composition. It controls co‐transcriptional processes such as splicing, polyadenylation,
Autor:
Lu Tang, Yue Chen, Fang Wang, Philipp Kapranov, Xiang You, DingDing Cai, Dongyang Xu, Denis V. Antonets, Xueer Han, Huifen Cao, Estelle Nicolas, Ye Cai, Huifang Wang, Maxim Ri, Yao Qi, Fan Gao, Yuri Vyatkin
Publikováno v:
BMC Biology
BMC Biology, Vol 19, Iss 1, Pp 1-24 (2021)
BMC Biology, Vol 19, Iss 1, Pp 1-24 (2021)
Background The majority of the human genome is transcribed in the form of long non-coding (lnc) RNAs. While these transcripts have attracted considerable interest, their molecular mechanisms of function and biological significance remain controversia
Autor:
Lisa, Muniz, Sandra, Lazorthes, Maxime, Delmas, Julien, Ouvrard, Marion, Aguirrebengoa, Didier, Trouche, Estelle, Nicolas
Publikováno v:
RNA Biology
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Long non-coding RNAs (ncRNAs) are major regulators of gene expression and cell fate. The INK4 locus encodes the tumour suppressor proteins p15INK4b, p16INK4a and p14ARF required for cell cycle arrest and whose expression increases during senescence.