Therapeutic efficacy of 166Holmium siloxane in microbrachytherapy of induced glioblastoma in minipig tumor model

Autor: Mehrdad Khoshnevis, Richard Brown, Sara Belluco, Ilyes Zahi, Luca Maciocco, Catherine Bonnefont-Rebeix, Elodie Pillet-Michelland, Jonathan Tranel, Thierry Roger, Christophe Nennig, Patrick Oudoire, Lionel Marcon, Olivier Tillement, Cédric Louis, Hélène Gehan, Manuel Bardiès, Maurizio Mariani, Valeria Muzio, Jean-Philippe Meunier, Charlotte Duchemin, Nathalie Michel, Estelle N’Tsiba, Ferid Haddad, Thierry Buronfosse, Claude Carozzo, Frédérique Ponce

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

Glioblastoma is considered the most common malignant primary tumor of central nervous system. In spite of the current standard and multimodal treatment, the prognosis of glioblastoma is poor. For this reason, new therapeutic approaches need to be dev

Externí odkaz: https://doaj.org/article/8aada16306dc42f0904f1ec20a17adaf

Coupling a gamma-ray detector with asymmetrical flow field flow fractionation (AF4): Application to a drug-delivery system for alpha-therapy

Autor: Estelle N’tsiba, Gilles Montavon, Marie Mougin-Degraef, Sandrine Huclier-Markai, Alicia Grivaud-Le Du, Jacques Barbet

Publikováno v: Journal of Chromatography A
Journal of Chromatography A, 2018, 1573, pp.107-114. ⟨10.1016/j.chroma.2018.08.065⟩
Journal of Chromatography A, Elsevier, 2018, 1573, pp.107-114. ⟨10.1016/j.chroma.2018.08.065⟩

International audience; Alpha-particle-emitting radionuclides have been the subject of considerable investigation as cancer ther-apeutics, sincethey have the advantages of highpotency and specificity. Among ␣-emitting radionuclides that are medical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf073f148f3c8c241ac89606d00c290
https://www.hal.inserm.fr/inserm-01900710/document