Výsledky vyhledávání - "Estela Trebicka"

Akademický článek

Tumor necrosis factor α inhibits expression of the iron regulating hormone hepcidin in murine models of innate colitis.

Autor: Nanda Kumar N Shanmugam, Shiri Ellenbogen, Estela Trebicka, Lijian Wang, Subhankar Mukhopadhyay, Adam Lacy-Hulbert, Carey Ann Gallini, Wendy S Garrett, Bobby J Cherayil

Publikováno v: PLoS ONE, Vol 7, Iss 5, p e38136 (2012)

Abnormal expression of the liver peptide hormone hepcidin, a key regulator of iron homeostasis, contributes to the pathogenesis of anemia in conditions such as inflammatory bowel disease (IBD). Since little is known about the mechanisms that control

Externí odkaz: https://doaj.org/article/9defec2c10fa44c791073893257377ba

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Intestinal Inflammation Leads to a Long-lasting Increase in Resistance to Systemic Salmonellosis that Requires Macrophages But Not B or T Lymphocytes at the Time of Pathogen Challenge

Autor: Chien-wen Su, Kejie Chen, Bobby J. Cherayil, Nanda Kumar N. Shanmugam, Hai Ning Shi, Estela Trebicka

Publikováno v: Inflammatory Bowel Diseases. 21:2758-2765

BACKGROUND Intestinal inflammation is associated with systemic translocation of commensal antigens and the consequent activation of B and T lymphocytes. The long-term consequences of such immune activation are not completely understood. METHODS C57BL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997e2bf168aa556732230208541b7fbc
https://doi.org/10.1097/mib.0000000000000544

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Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens

Autor: Jos Boekhorst, Thijs J. W. Richters, Coby M. Laarakkers, Guus A. M. Kortman, Erwin T. Wiegerinck, Bobby J. Cherayil, Dorine W. Swinkels, Harold Tjalsma, Estela Trebicka, Albert Bolhuis, Rian Roelofs, Harro M. Timmerman, Nanda Kumar N. Shanmugam, Michelle L. M. Mulder

Publikováno v: European Journal of Immunology. 45:2553-2567

Orally administrated iron is suspected to increase susceptibility to enteric infections among children in infection endemic regions. Here we investigated the effect of dietary iron on the pathology and local immune responses in intestinal infection m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b26ef17c9fc726d64b848430cd82fc7d
https://doi.org/10.1002/eji.201545642

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Effect of Human Immunodeficiency Virus Infection on Plasma Bactericidal Activity against Salmonella enterica Serovar Typhimurium

Autor: Estela Trebicka, Bobby J. Cherayil, Nanda Kumar N. Shanmugam, Anastassia Mikhailova, Galit Alter

Publikováno v: Clinical and Vaccine Immunology. 21:1437-1442

Individuals with human immunodeficiency virus (HIV) infection have increased susceptibility to invasive disease caused by Salmonella enterica serovar Typhimurium. Studies from Africa have suggested that this susceptibility is related in part to the d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ebc8bae80bdcdb139f628d696597105
https://doi.org/10.1128/cvi.00501-14

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Intestinal Inflammation Modulates Expression of the Iron-Regulating Hormone Hepcidin Depending on Erythropoietic Activity and the Commensal Microbiota

Autor: Nanda Kumar N. Shanmugam, Estela Trebicka, Ling-lin Fu, Bobby J. Cherayil, Hai Ning Shi

Publikováno v: The Journal of Immunology. 193:1398-1407

States of chronic inflammation such as inflammatory bowel disease are often associated with dysregulated iron metabolism and the consequent development of an anemia that is caused by maldistribution of iron. Abnormally elevated expression of the horm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79f05f5dc236674d60ee02e35f53b61f
https://doi.org/10.4049/jimmunol.1400278

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The bone morphogenetic protein–hepcidin axis as a therapeutic target in inflammatory bowel disease

Autor: Shiri Ellenbogen, Charles C. Hong, Bobby J. Cherayil, Herbert Y. Lin, Ying Fu, Estela Trebicka, Jodie L. Babitt, Lijian Wang

Publikováno v: Inflammatory Bowel Diseases. 18:112-119

Background: A debilitating anemia associated with low serum iron often accompanies inflammatory bowel disease (IBD). Increased production of the iron regulatory hormone hepcidin is implicated in its pathogenesis and may also contribute to the inflamm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49def8a1098129b78b5301f36c5fe9e7
https://doi.org/10.1002/ibd.21675

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Regulation of Lipopolysaccharide-Induced Translation of Tumor Necrosis Factor-Alpha by the Toll-Like Receptor 4 Adaptor Protein TRAM

Autor: Bobby J. Cherayil, Katherine A. Fitzgerald, Shizuo Akira, Lijian Wang, Jonathan C. Kagan, Ying Fu, Estela Trebicka, Lisa Waggoner

Publikováno v: Journal of Innate Immunity. 3:437-446

Lipopolysaccharide (LPS)-induced production of tumor necrosis factor (TNF)-α requires the recruitment of two pairs of adaptors to the Toll-like receptor 4 cytoplasmic domain. The contribution of one pair – Toll-interleukin-1 receptor domain-contai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b8793aee8a11935a6d160f85423a55
https://doi.org/10.1159/000324833

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Siderocalin inhibits the intracellular replication ofMycobacterium tuberculosisin macrophages

Autor: Niels Borregaard, Megan Murray, Bobby J. Cherayil, Lijian Wang, Erin E. Johnson, Estela Trebicka, Lynne Harrington, Andreas Sandgren, C. V. Srikanth

Publikováno v: FEMS Immunology & Medical Microbiology. 58:138-145

Siderocalin is a secreted protein that binds to siderophores to prevent bacterial iron acquisition. While it has been shown to inhibit the growth of Mycobacterium tuberculosis (M.tb) in extracellular cultures, its effect on this pathogen within macro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf68a261b53106a15afcdaded6c5052
https://doi.org/10.1111/j.1574-695x.2009.00622.x

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Role of antilipopolysaccharide antibodies in serum bactericidal activity against Salmonella enterica serovar Typhimurium in healthy adults and children in the United States

Autor: Bryan P. Hurley, Estela Trebicka, Waheed Pirzai, Susan Jacob, Bobby J. Cherayil

Publikováno v: Clinical and vaccine immunology : CVI. 20(10)

Recent observations from Africa have rekindled interest in the role of serum bactericidal antibodies in protecting against systemic infection withSalmonella entericaserovar Typhimurium. To determine whether the findings are applicable to other popula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5bf677ace7ea92c38075e4c954fe1d
https://pubmed.ncbi.nlm.nih.gov/23904457

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Tumor necrosis factor α inhibits expression of the iron regulating hormone hepcidin in murine models of innate colitis

Autor: Shiri Ellenbogen, Nanda Kumar N. Shanmugam, Adam Lacy-Hulbert, Bobby J. Cherayil, Carey Ann Gallini, Lijian Wang, Estela Trebicka, Wendy S. Garrett, Subhankar Mukhopadhyay

Publikováno v: PLoS ONE, Vol 7, Iss 5, p e38136 (2012)
PLoS ONE

BACKGROUND: Abnormal expression of the liver peptide hormone hepcidin, a key regulator of iron homeostasis, contributes to the pathogenesis of anemia in conditions such as inflammatory bowel disease (IBD). Since little is known about the mechanisms t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fabc02d260d9625de88bafb7f951982
http://europepmc.org/articles/PMC3365004?pdf=render

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