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pro vyhledávání: '"Estela Nieves"'
Autor:
Daniel Granados-Fuentes, Estela Nieves, J. Christian Gillin, Rafael J. Salin-Pascual, Lourdes Galicia-Polo
Publikováno v:
Biological Psychiatry. 33:188-193
The muscarinic antagonist biperiden produces a dose-dependent inhibition of (REM) sleep on acute administration. The present study addressed the possibility of pharmacological tolerance after repeated biperiden administration. Six healthy volunteers
Biperiden administration during REM sleep deprivation diminished the frequency of REM sleep attempts
Autor:
Timothy Roehrs, Estela Nieves, Lourdes Galicia-Polo, Rafael J. Salín-Pascual, Thomas Roth, Daniel Grandos-Fuentes
Publikováno v:
Sleep. 15(3)
Sixteen subjects were assigned to a group using either placebo or biperiden, with eight subjects in each group. Both groups were studied for one acclimatization night, one baseline night, four nights of rapid eye movement (REM) sleep deprivation and