Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Estela Núñez-Manchón"'
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Vaccination is the most effective method to date to prevent viral diseases. It intends to mimic a naturally occurring infection while avoiding the disease, exposing our bodies to viral antigens to trigger an immune response that will protect us from
Externí odkaz:
https://doaj.org/article/eafe543a960a4808b6765f4110b58474
Autor:
Giancarlo Castellano, David Medel, Marc Otero-Mateo, Martí Farrera-Sal, Eneko Villanueva, Cristina Fillat, Ramon Alemany, Rafael Moreno, Estela Núñez-Manchón
Publikováno v:
NAR Cancer
Arming oncolytic adenoviruses with therapeutic transgenes is a well-established strategy for multimodal tumour attack. However, this strategy sometimes leads to unexpected attenuated viral replication and a loss of oncolytic effects, preventing these
Autor:
Rafael Moreno, Ramon Alemany, Estela Núñez-Manchón, Jana de Sostoa, Cristina Fillat, Martí Farrera-Sal, Miriam Bazan-Peregrino
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 14
Dipòsit Digital de la UB
Universidad de Barcelona
International Journal of Molecular Sciences, Vol 21, Iss 5158, p 5158 (2020)
Volume 21
Issue 14
Dipòsit Digital de la UB
Universidad de Barcelona
International Journal of Molecular Sciences, Vol 21, Iss 5158, p 5158 (2020)
Oncolytic adenoviruses (OAds) present limited efficacy in clinics. The insertion of therapeutic transgenes into OAds genomes, known as &ldquo
arming OAds&rdquo
has been the main strategy to improve their therapeutic potential. Different app
arming OAds&rdquo
has been the main strategy to improve their therapeutic potential. Different app
Autor:
Meritxell Gironella, Estela Núñez-Manchón, Miriam Cuatrecasas, Eva C. Vaquero, Xavier Bofill-De Ros, Maria L. Arbonés, Cristina Fillat, Jacopo Boni, Susana de la Luna, Jeroni Luna
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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[Background and aims]: Pancreatic ductal adenocarcinoma (PDAC) is a very aggressive tumour with a poor prognosis using current treatments. Targeted therapies may offer a new avenue for more effective strategies. Dual-specificity tyrosine regulated ki