Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Estela M. G. Lourenço"'
1
Akademický článek
Identification of a Selective PDE4B Inhibitor From Bryophyllum pinnatum by Target Fishing Study and In Vitro Evaluation of Quercetin 3-O-α-L-Arabinopyranosyl-(1→2)-O-α-L-Rhamnopyranoside
Autor: Estela M. G. Lourenço, Júlia M. Fernandes, Vinícius de F. Carvalho, Raphael Grougnet, Marco A. Martins, Alessandro K. Jordão, Silvana M. Zucolotto, Euzébio G. Barbosa
Publikováno v: Frontiers in Pharmacology, Vol 10 (2020)
Natural products are considered an important source of bioactive compounds especially in biodiversity-rich countries like Brazil. The identification of potential targets is crucial to the development of drugs from natural sources. In this context, in
Externí odkaz: https://doaj.org/article/c188901e3ca045b294d5cfc76a6422fe
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2
Akademický článek
Mechanism of action and synergistic effect of Eugenia uniflora extract in Candida spp.
Autor: Luanda B F C Souza, Aurélio de Oliveira Bento, Estela M G Lourenço, Magda R A Ferreira, Wogenes N Oliveira, Luiz Alberto L Soares, Euzébio G Barbosa, Hugo A O Rocha, Guilherme Maranhão Chaves
Publikováno v: PLoS ONE, Vol 19, Iss 8, p e0303878 (2024)
The limited arsenal of antifungal drugs have prompted the search for novel molecules with biological activity. This study aimed to characterize the antifungal mechanism of action of Eugenia uniflora extract and its synergistic activity with commercia
Externí odkaz: https://doaj.org/article/8dda8bda603540058a22da4a1b3cbe9f
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3
Erythroxylum pungens Tropane Alkaloids: GC-MS Analysis and the Bioactive Potential of 3-(2-methylbutyryloxy)tropan-6,7-diol in Zebrafish (Danio rerio)
Autor: Leandro de Santis Ferreira, Ana Carolina Luchiari, Arthur Germano Fett-Neto, Estela M G Lourenço, Fernanda Priscila Santos Reginaldo, Euzébio Guimarães Barbosa, Maria Elisa Leite Ferreira, Raquel Brandt Giordani, Letícia Gondim Lambert Moreira, Alberto José Cavalheiro, Jose Angelo Silveira Zuanazzi
Publikováno v: Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2021-06-25T19:56:02Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-11-11 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ebbb1bebddd59481153003b50bf7f53
https://doi.org/10.1055/a-1264-4302
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4
In Silico Study, Physicochemical, and In Vitro Lipase Inhibitory Activity of α,β-Amyrenone Inclusion Complexes with Cyclodextrins
Autor: Ádley Antonini Neves de Lima, Paulo Henrique de Santana Miranda, Luana Carvalho de Oliveira, Emerson Silva Lima, Valéria Costa da Silva, Ricardo Neves Marreto, Márcia de Jesus Amazonas da Silva, Euzébio Guimarães Barbosa, Danielle Lima Bezerra de Menezes, Estela M G Lourenço, Attilio Converti, Valdir Florêncio da Veiga Junior
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 9882, p 9882 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 18
α,β-amyrenone (ABAME) is a triterpene derivative with many biological activities
however, its potential pharmacological use is hindered by its low solubility in water. In this context, the present work aimed to develop inclusion complexes (ICs
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e484102f01917c926f068e87bf3cc1d7
https://www.mdpi.com/1422-0067/22/18/9882
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5
Molecular modeling of a series of dehydroquinate dehydratase type II inhibitors of Mycobacterium tuberculosis and design of new binders
Autor: Priscilla Suene de Santana Nogueira Silverio, Estela M G Lourenço, Euzébio Guimarães Barbosa, Alessandro K. Jordão, Alexander M. S. Morais, Paulo Henrique de Santana Miranda, Pedro Igor Câmara de Oliveira
Publikováno v: Molecular Diversity. 25:1-12
Tuberculosis, caused by Mycobacterium tuberculosis (M. tuberculosis), is still responsible for a large number of fatal cases, especially in developing countries with alarming rates of incidence and prevalence worldwide. Mycobacterium tuberculosis has
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::444f7a4ed501cdf0d064b1fa72ef3019
https://doi.org/10.1007/s11030-019-10020-1
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7
Mass spectrometry characterization of Commiphora leptophloeos leaf extract and preclinical evaluation of toxicity and anti-inflammatory potential effect
Autor: Hugo Alexandre Oliveira Rocha, Silvana Maria Zucolotto, Jovelina Samara Ferreira Alves, Wagner Vilegas, Ana C. Zanatta, Éder Galinari, Matheus F. Fernandes-Pedrosa, Manoela Torres-Rêgo, Allanny Alves Furtado, Renato Dantas-Medeiros, Estela M G Lourenço, Thiago Antônio de Sousa Araújo, Gerlane Coelho Bernardo Guerra
Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2021-06-25T10:33:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-10 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Ethnopharmacological relevance: Commiphora leptophloeos (Mart.) J.B.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09992c159de27a6e2c1a37946f0cfec
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8
Planning new Trypanosoma cruzi CYP51 inhibitors using QSAR studies
Autor: Priscilla Suene de Santana Nogueira Silverio, Pedro Igor Camara de Oliveira, Euzébio Guimarães Barbosa, Paulo Henrique de Santana Miranda, Estela M G Lourenço
Publikováno v: Molecular diversity. 25(4)
Chagas disease kills over 10,000 people per year, and approximately 8 million people are infected by Trypanosoma cruzi. The reference drug for treatment of the disease, benznidazole, is the same since the 70s. In recent years, many CYP51 inhibitors w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f8c75c188d05a3c9c8ca3f6f3dca19
https://pubmed.ncbi.nlm.nih.gov/32557280
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10
Identification of a Selective PDE4B Inhibitor From Bryophyllum pinnatum by Target Fishing Study and In Vitro Evaluation of Quercetin 3-O-α-L-Arabinopyranosyl-(1→2)-O-α-L-Rhamnopyranoside
Autor: Marco A. Martins, Raphaël Grougnet, Júlia Morais Fernandes, Alessandro K. Jordão, Vinicius F. Carvalho, Euzébio Guimarães Barbosa, Estela M G Lourenço, Silvana Maria Zucolotto
Publikováno v: Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 10 (2020)
Natural products are considered an important source of bioactive compounds especially in biodiversity-rich countries like Brazil. The identification of potential targets is crucial to the development of drugs from natural sources. In this context, in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06dd78e3dff27c821494ad7883efc776
http://europepmc.org/articles/PMC6987432
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