Výsledky vyhledávání - "Estela González‐Gualda"

Akademický článek

Targeting senescent cells in translational medicine

Autor: Marta Paez‐Ribes, Estela González‐Gualda, Gary J Doherty, Daniel Muñoz‐Espín

Publikováno v: EMBO Molecular Medicine, Vol 11, Iss 12, Pp 1-19 (2019)

Abstract Organismal ageing is a complex process driving progressive impairment of functionality and regenerative potential of tissues. Cellular senescence is a state of stable cell cycle arrest occurring in response to damage and stress and is consid

Externí odkaz: https://doaj.org/article/f1552ee743934e8493ca70abe9e11fb1

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Akademický článek

Inexhaustible hair-cell regeneration in young and aged zebrafish

Autor: Filipe Pinto-Teixeira, Oriol Viader-Llargués, Elen Torres-Mejía, Melissa Turan, Estela González-Gualda, Laura Pola-Morell, Hernán López-Schier

Publikováno v: Biology Open, Vol 4, Iss 7, Pp 903-909 (2015)

Animals have evolved two general strategies to counter injury and maintain physiological function. The most prevalent is protection by isolating vital organs into body cavities. However, protection is not optimal for sensory systems because their ext

Externí odkaz: https://doaj.org/article/4240e024fa9c4369b402d0956ebe80a3

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A tumour-promoting senescent secretome triggered by platinum chemotherapy exploits a targetable TGFβR1/Akt-mTOR axis in lung cancer

Platinum-based chemotherapy is commonly used for non-small cell lung cancer (NSCLC) treatment, yet clinical outcomes remain poor. Cellular senescence and its associated secretory phenotype (SASP) can have multiple tumour-promoting activities, althoug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b2bb945606577f05bb5051e573af309
https://doi.org/10.1101/2022.08.01.502019

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Contributors

Autor: Shariq Abid, Serge Adnot, Alvar Agusti, Delphine Beaulieu, Anil Bhushan, Thomas G. Bird, Emmanuelle Born, Marielle Breau, Alexander F. Chin, Jennifer H. Elisseeff, Zulrahman Erlangga, Konstantinos Evangelou, Rosa Faner, Joshua N. Farr, Eleni Georgakopoulou, Estela González-Gualda, Vassilis G. Gorgoulis, Elise Gray-Gaillard, Jin Han, Fernanda Hernandez-Gonzalez, Amal Houssaini, Michael D. Jensen, Diana Jurk, Goro Katsuumi, Sundeep Khosla, Christos Kiourtis, James L. Kirkland, Marta Kovatcheva, Larissa Lipskaia, Jose Alberto López-Domínguez, David Macías, Elisabeth Marcos, Mate Maus, Anette Melk, Kathleen Meyer, John Michel, Tohru Minamino, Satomi Miwa, David G. Monroe, Daniel Muñoz-Espín, Hui-Ling Ou, Allyson K. Palmer, Nayuta Saito, Roland Schmitt, Jacobo Sellares, Manuel Serrano, Myong-Hee Sung, Tamara Tchkonia, Peter J. Thompson, Thomas von Zglinicki, Tengfei Wan, Peisu Zhang

Publikováno v: Cellular Senescence in Disease ISBN: 9780128225141

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::86b75ae32a421dd67dc1780eb3c723f4
https://doi.org/10.1016/b978-0-12-822514-1.01002-6

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A Two-Photon Probe Based on Naphthalimide-Styrene Fluorophore for the

Autor: Beatriz, Lozano-Torres, Juan F, Blandez, Irene, Galiana, José A, Lopez-Dominguez, Miguel, Rovira, Marta, Paez-Ribes, Estela, González-Gualda, Daniel, Muñoz-Espín, Manuel, Serrano, Félix, Sancenón, Ramón, Martínez-Máñez

Publikováno v: Analytical Chemistry

Cellular senescence is a state of stable cell cycle arrest that can negatively affect the regenerative capacities of tissues and can contribute to inflammation and the progression of various aging-related diseases. Advances in the in vivo detection o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d8bc6a5add68290a66a8f0c3ee311a39
https://pubmed.ncbi.nlm.nih.gov/33502178

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A Two-Photon Probe Based on Naphthalimide-Styrene Fluorophore for the In Vivo Tracking of Cellular Senescence

Autor: Irene Galiana, Estela González-Gualda, Félix Sancenón, Marta Paez-Ribes, Ramón Martínez-Máñez, Beatriz Lozano-Torres, Manuel Serrano, Miguel Rovira, Daniel Muñoz-Espín, Juan F. Blandez, Jose Alberto Lopez-Dominguez

Publikováno v: Analytical Chemistry
Dipòsit Digital de la UB
Universidad de Barcelona
ANALYTICAL CHEMISTRY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

[EN] Cellular senescence is a state of stable cell cycle arrest that can negatively affect the regenerative capacities of tissues and can contribute to inflammation and the progression of various aging-related diseases. Advances in the in vivo detect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcebf90fe7b83e3080971be06610b7a8

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A guide to assessing cellular senescence in vitro and in vivo

Autor: Andrew G Baker, Ljiljana Fruk, Estela González-Gualda, Daniel Muñoz-Espín

Publikováno v: The FEBS journalReferences. 288(1)

Cellular senescence is a physiological mechanism whereby a proliferating cell undergoes a stable cell cycle arrest upon damage or stress and elicits a secretory phenotype. This highly dynamic and regulated cellular state plays beneficial roles in phy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b37102adac076e152c60a6a48df5f97
https://pubmed.ncbi.nlm.nih.gov/32961620

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Galacto-conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity

Publikováno v: AGING CELL
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
Aging Cell
Aging cell
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia

[EN] Pharmacologically active compounds with preferential cytotoxic activity for senescent cells, known as senolytics, can ameliorate or even revert pathological manifestations of senescence in numerous preclinical mouse disease models, including can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59dddccd593a204ddbd658e99660a27f
https://fundanet.cipf.es/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=3516

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Targeting senescent cells in translational medicine

Autor: Estela González-Gualda, Marta Paez-Ribes, Gary J. Doherty, Daniel Muñoz-Espín

Publikováno v: EMBO Molecular Medicine, Vol 11, Iss 12, Pp n/a-n/a (2019)
EMBO Molecular Medicine

Organismal ageing is a complex process driving progressive impairment of functionality and regenerative potential of tissues. Cellular senescence is a state of stable cell cycle arrest occurring in response to damage and stress and is considered a ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744e397cdbf0884019dfb624e93ccb51
https://doi.org/10.15252/emmm.201810234

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Inexhaustible hair-cell regeneration in young and aged zebrafish

Autor: Hernán López-Schier, Laura Pola-Morell, Estela González-Gualda, Melissa Turan, Oriol Viader-Llargués, Elen Torres-Mejía, Filipe Pinto-Teixeira

Publikováno v: Europe PubMed Central
Biol. Open 4, 903-909 (2015)
CIÊNCIAVITAE
Biology Open
Biology Open, Vol 4, Iss 7, Pp 903-909 (2015)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a386bf2c952d5bb493a49034bb191b
http://europepmc.org/abstract/med/26002931

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