Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Esteban Nova"'
Autor:
Javiera Arcos, Felipe Grunenwald, Denisse Sepulveda, Carolina Jerez, Valentina Urbina, Tomas Huerta, Paulina Troncoso-Escudero, Daniel Tirado, Angela Perez, Rodrigo Diaz-Espinoza, Esteban Nova, Ulrich Kubitscheck, Juan Eduardo Rodriguez-Gatica, Claudio Hetz, Jorge Toledo, Pablo Ahumada, Diego Rojas-Rivera, Elisa Martín-Montañez, María Garcia-Fernandez, René L. Vidal
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Parkinson’s disease (PD) is the second most common late-onset neurodegenerative disease and the predominant cause of movement problems. PD is characterized by motor control impairment by extensive loss of dopaminergic neurons in the substa
Externí odkaz:
https://doaj.org/article/aba55e77f23e47fea777fe13c893bc03
Publikováno v:
Archives of Biochemistry and Biophysics. 621:46-53
Amyloids are polypeptide aggregates involved in many pathologies including Alzheimer's disease. Amyloid assembly is a complex process affected by different interactions including hydrogen bonding, van der Waals forces and electrostatic interactions.
Autor:
Esteban Nova, Octavio Monasterio, Claudio Castillo-Caceres, Raul Araya-Secchi, Rodrigo Diaz-Espinoza, Eva Duran-Meza
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1865:129729
Background Amyloids are highly ordered polypeptide aggregates stabilized by a beta-sheet structural core. Though classically associated to pathology, reports on novel functional roles of these proteins have increasingly emerged in the past decade. Mo
Publikováno v:
Archives of Biochemistry and Biophysics. 687:108372
research grants CONICYT PAI/CONCURSO NACIONAL INSERCION EN LA ACADEMIA, CONVOCATORIA 2016 PAI79160143 CONICYT/FONDECYT/3150054 CONICYT/FONDECYT/11160554
Autor:
Juan Ramírez-Estrada, Joydeep Bhattacharjee, María Inés Becker, Cecilia León, Fabián Salazar, Sebastián Abades, Esteban Nova, Loren D. Hayes, Luis A. Ebensperger
Publikováno v:
PHYSIOLOGY & BEHAVIOR
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
One hypothesis largely examined in social insects is that cooperation in the context of breeding benefits individuals through decreasing the burden of immunocompetence and provide passive immunity through social contact. Similarly, communal rearing i
Autor:
María Inés Becker, Andrea González, Alfredo E. De Ioannes, Esteban Nova, Augusto Manubens, Miguel Del Campo, Jorge Ferreira
Publikováno v:
Biochimica et biophysica acta. Proteins and proteomics. 1865(12)
Hemocyanins have highly conserved copper-containing active sites that bind oxygen. However, structural differences among the hemocyanins of various mollusks may affect their physicochemical properties. Here, we studied the oxygen-binding cooperativit
Publikováno v:
Biochemical and biophysical research communications. 482(4)
Amyloids are protein aggregates of highly regular structure that are involved in diverse pathologies such as Alzheimer's and Parkinson's disease. Recent evidence has shown that under certain conditions, small peptides can self-assemble into amyloids
Publikováno v:
EUROPEAN JOURNAL OF IMMUNOLOGY
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Hemocyanins, which boost the immune system of mammals, have been used as carrier-adjuvants to promote Ab production against haptens and peptides, as immunostimulants during therapy for bladder carcinoma and as a component in therapeutic vaccines for
Autor:
Octavio Monasterio, Rosalba Lagos, Julio Benites, Julien Verrax, Pedro Buc Calderon, Daniel Maturana, Cristian Escobar, Jaime A. Valderrama, Eunices Gutierrez, Esteban Nova, Felipe Villanelo
Publikováno v:
Biochemical and biophysical research communications. 466(3)
Dihydroxynaphthyl aryl ketones 1-5 have been evaluated for their abilities to inhibit microtubule assembly and the binding to tubulin. Compounds 3, 4 and 5 displayed competitive inhibition against colchicine binding, and docking analysis showed that
Publikováno v:
FEBS Letters. 374:165-168
The use of 3-fluoro-tyrosine as an alternative substrate for the enzyme tubulin:tyrosine ligase which catalyzes the incorporation of tyrosine into the alpha-tubulin subunit was investigated. The incorporation of tyrosine into tubulin was inhibited co