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Akademický článek
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Autor:
Esteban Mazzoni
Publikováno v:
Development. 147
Hox genes instruct positional identity along the anterior-posterior axis of the animal body. A new paper in Development addresses the question of how similar Hox genes can define diverse cell fates, using mouse motor neurons as a model. To hear more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f8d4bfe660877d0bca6148ad76736b4
https://doi.org/10.1242/dev.197715
https://doi.org/10.1242/dev.197715
Akademický článek
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Autor:
Ana Paula Zen Petisco Fiore, Shuvadeep Maity, Lauren Jeffery, Disi An, Justin Rendleman, Dylan Iannitelli, Hyungwon Choi, Esteban Mazzoni, Christine Vogel
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113885- (2024)
Summary: Amyotrophic lateral sclerosis damages proteostasis, affecting spinal and upper motor neurons earlier than a subset of cranial motor neurons. To aid disease understanding, we exposed induced cranial and spinal motor neurons (iCrMNs and iSpMNs
Externí odkaz:
https://doaj.org/article/ec67cb62c095414cb313530ab059cdee
Autor:
Havva Ortabozkoyun, Pin-Yao Huang, Hyunwoo Cho, Aristotelis Tsirigos, Esteban Mazzoni, Danny Reinberg
Publikováno v:
bioRxiv
CCCTC-binding factor (CTCF) and MAZ are recognized insulators required for shielding repressed posterior genes from active anterior genes within theHoxclusters during motor neuron (MN) differentiation. CTCF and MAZ interact independently with cohesin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f2b1c2810d598f29aebb5e5464f54a9
https://doi.org/10.1101/2023.04.25.538167
https://doi.org/10.1101/2023.04.25.538167
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 10, p e1005795 (2017)
Genomic loci with regulatory potential can be annotated with various properties. For example, genomic sites bound by a given transcription factor (TF) can be divided according to whether they are proximal or distal to known promoters. Sites can be fu
Externí odkaz:
https://doaj.org/article/8b8ae0ce33ee4e7eab365252c246a60b
Autor:
Ana Paula Zen Petisco Fiore, Shuvadeep Maity, Disi An, Justin Rendleman, Dylan Iannitelli, Hyungwon Choi, Esteban Mazzoni, Christine Vogel
Amyotrophic Lateral Sclerosis (ALS) is a fatal adult neurodegenerative disease characterized by proteostasis dysregulation, resulting in progressive loss of spinal and upper motor neurons. A subset of cranial motor neurons resistant to ALS-stress sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50f393a58562ae853e44da6d44296fa5
https://doi.org/10.1101/2022.04.10.487765
https://doi.org/10.1101/2022.04.10.487765
Publikováno v:
Science (New York, N.Y.). 341(6147)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::52f06e8854ff39e457754eadbf6dc72d
https://pubmed.ncbi.nlm.nih.gov/23950522
https://pubmed.ncbi.nlm.nih.gov/23950522
Publikováno v:
Molecular cancer research : MCR. 1(10)
We have investigated the role of a classical isoform of protein kinase C (PKCgamma) in promoting immortalized mammary cell tumorigenesis in vivo and the contribution of proteases and adhesion molecules to this process. We hypothesized that overexpres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a1f6ab7d5e1af643d49ab0715fd7470
https://pubmed.ncbi.nlm.nih.gov/12939403
https://pubmed.ncbi.nlm.nih.gov/12939403
Autor:
Alejandro, Español, Ana M, Eiján, Esteban, Mazzoni, Lilia, Davel, María A, Jasnis, Eugenia, Sacerdote De Lustig, María E, Sales
Publikováno v:
International journal of molecular medicine. 9(6)
Investigations on the influence of the parasympathetic nervous system via muscarinic signaling in tumor progression have produced contradictory evidence. We investigated the expression of muscarinic acetylcholine receptors (mAchR) and their intracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b4aa4d5cdd599bf8c8d6e701e294e80
https://pubmed.ncbi.nlm.nih.gov/12011984
https://pubmed.ncbi.nlm.nih.gov/12011984