Relative hypercoagulopathy of the SARS-CoV-2 Beta and Delta variants when compared to the less severe Omicron variants is related to TEG parameters, the extent of fibrin amyloid microclots, and the severity of clinical illness

Autor: Lize M. Grobbelaar, Arneaux Kruger, Chantelle Venter, Este M. Burger, Gert J. Laubscher, Tongai G. Maponga, Maritha J. Kotze, Hau C. Kwaan, Joseph B. Miller, Daniel Fulkerson, Wei Huff, Eric Chang, Grant Wiarda, Connor M. Bunch, Mark M. Walsh, Syed Raza, Mahmud Zamlut, Hunter B. Moore, Ernest E. Moore, Matthew D. Neal, Douglas B. Kell, Etheresia Pretorius

Publikováno v: Grobbelaar, L M, Kruger, A, Venter, C, Burger, E M, Laubscher, G J, Maponga, T G, Kotze, M J, Kwaan, H C, Miller, J B, Fulkerson, D, Huff, W, Chang, E, Wiarda, G, Bunch, C M, Walsh, M M, Raza, S, Zamlut, M, Moore, H B, Moore, E E, Neal, M D, Kell, D B & Pretorius, E 2022, ' Relative Hypercoagulopathy of the SARS-CoV-2 Beta and Delta Variants when Compared to the Less Severe Omicron Variants Is Related to TEG Parameters, the Extent of Fibrin Amyloid Microclots, and the Severity of Clinical Illness ', Seminars in Thrombosis and Hemostasis, vol. 48, no. 7, pp. 858-868 . https://doi.org/10.1055/s-0042-1756306

Earlier variants of SARS-CoV-2 have been associated with plasma hypercoagulability (as judged by thromboelastography) and an extensive formation of fibrin amyloid microclots, which are considered to contribute to the pathology of the coronavirus 2019

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c09bdf8184d63cd22bdfcab2a28c27
https://doi.org/10.21203/rs.3.rs-1970823/v1