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The mRNA-LNP platform's lipid nanoparticle component used in preclinical vaccine studies is highly inflammatory.

Autor: Ndeupen S; Thomas Jefferson University, Department of Microbiology and Immunology, Philadelphia, PA., Qin Z; Thomas Jefferson University, Department of Microbiology and Immunology, Philadelphia, PA., Jacobsen S; Thomas Jefferson University, Department of Microbiology and Immunology, Philadelphia, PA., Estanbouli H; Thomas Jefferson University, Department of Microbiology and Immunology, Philadelphia, PA., Bouteau A; Thomas Jefferson University, Department of Microbiology and Immunology, Philadelphia, PA., Igyártó BZ; Thomas Jefferson University, Department of Microbiology and Immunology, Philadelphia, PA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2021 Jul 23. Date of Electronic Publication: 2021 Jul 23.